P-POD: Princeton Protein Orthology Database: GO3/Jaccard181

This family has 90 members: 2 Caenorhabditis elegans, 17 Danio rerio, 5 Drosophila melanogaster, 11 Gallus gallus, 14 Homo sapiens, 13 Mus musculus, 14 Rattus norvegicus, 7 Saccharomyces cerevisiae, 7 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Jaccard181
90 members.
OrganismProtein (Synonyms)DescriptionAmiGO
C. elegansUniProtKB:Q8I4C9 · WB:WBGene00006795 (Y50E8A.4 · unc-61)⌘
C. elegansWB:WBGene00006793 (W09C5.2 · unc-59) · UniProtKB:Q9U334⌘
D. rerioENSEMBL:ENSDARP00000046846
D. rerioENSEMBL:ENSDARP00000020193
D. rerioUniProtKB:A2BGU8 · ZFIN:ZDB-GENE-050522-375 (sept3)septin 3⌘
D. rerioUniProtKB:A0JMF4 · ZFIN:ZDB-GENE-061103-265 (sept7b)septin 7b⌘
D. rerioZFIN:ZDB-GENE-070424-28 (zgc:162239) · UniProtKB:A3KNM3⌘
D. rerioUniProtKB:A4FUM1 · ZFIN:ZDB-GENE-070424-3 (sept8b)septin 8b⌘
D. rerioUniProtKB:Q32LU3 · ZFIN:ZDB-GENE-051120-87 (sept4a)septin 4a⌘
D. rerioUniProtKB:Q4V966 · ZFIN:ZDB-GENE-040426-1008 (sept7a)septin 7a⌘
D. rerioUniProtKB:Q568B3 · ZFIN:ZDB-GENE-050417-3 (sept10)septin 10⌘
D. rerioUniProtKB:Q58EK7 · ZFIN:ZDB-GENE-050327-17 (sept9b)septin 9b⌘
D. rerioUniProtKB:Q6AZC9 · ZFIN:ZDB-GENE-040808-43 (sept5b)septin 5b⌘
D. rerioUniProtKB:Q6P7X7 · ZFIN:ZDB-GENE-030131-9187 (sept9a)septin 9a⌘
D. rerioUniProtKB:Q6PBW0 · ZFIN:ZDB-GENE-030131-7868 (sept5a)septin 5a⌘
D. rerioUniProtKB:Q6PHD7 · ZFIN:ZDB-GENE-030131-1414 (sept6)septin 6⌘
D. rerioUniProtKB:Q7SXT0 · ZFIN:ZDB-GENE-030131-309 (sept8a)septin 8a⌘
D. rerioZFIN:ZDB-GENE-040426-1175 (zgc:63587) · UniProtKB:Q7SY26⌘
D. rerioUniProtKB:Q1JPX7 · ZFIN:ZDB-GENE-030131-911 (sept2)septin 2⌘
D. melanogasterUniProtKB:P40797 · FB:FBgn0013726 (CG8705 · pnut · l(2)02502 · E(sina)8 · PNUT · septin[Pnut] · peanut · anon-EST:Liang-2.18 · E(sina)44C · Pnut · septin · Septin · Peanut)Septin 3 · clone 2.18 · Enhancer of seven in absentia 8⌘
D. melanogasterUniProtKB:P42207 · FB:FBgn0011710 (Diff6 · anon-19Fa · tu1 · Septin-1 · Sep1 · CG1403 · sep1 · septin · iby)septin 1 · innocent bystander⌘
D. melanogasterUniProtKB:P54359 · FB:FBgn0014029 (sep2 · CG4173 · Septin-2 · septin-2 · Sep2 · septin)Myosin LC · septin 2⌘
D. melanogasterUniProtKB:Q7KLG8 · FB:FBgn0026361 (Sep · CG2916 · Septin-5 · sep5 · Sep5 · septin)Septin 5⌘
D. melanogasterFB:FBgn0030772 · UniProtKB:Q960I4
G. gallusNCBI:XP_425473 · ENTREZ:427899
G. gallusNCBI:XP_414648 · ENTREZ:416333
G. gallusNCBI:XP_416931 · ENTREZ:418732
G. gallusNCBI:XP_001234088 · ENTREZ:770762
G. gallusNCBI:XP_422654 · ENTREZ:424843
G. gallusNCBI:XP_420591 · ENTREZ:422635
G. gallusUniProtKB:Q5F3T2 (IPI00592494 · RCJMB04_7k22 · Septin · Q5F3T2) · ENTREZ:417347⌘
G. gallusUniProtKB:Q5F3T3 (RCJMB04_7k16 · Q5F3T3 · IPI00601203 · Septin) · ENTREZ:420741⌘
G. gallusUniProtKB:Q5F4B7 (Q5F4B7 · IPI00575569 · RCJMB04_1d3 · Septin) · ENTREZ:416778⌘
G. gallusUniProtKB:Q5ZM42 (Q5ZM42 · RCJMB04_3d14 · Septin · IPI00572994) · ENTREZ:422369⌘
G. gallusUniProtKB:Q5ZMH1 (SEPT2_CHICK · Septin-2 · SEPT2 · RCJMB04_2a21 · IPI00584652 · Q5ZMH1) · ENTREZ:416777⌘
H. sapiensENSEMBL:ENSG00000186522 · UniProtKB:Q9P0V9 (IPI00153055 · IPI00374970 · Q9P0V9 · SEP10_HUMAN · SEPT10 · Septin-10)⌘
H. sapiensENSEMBL:ENSG00000138758 · UniProtKB:Q9NVA2 (Septin-11 · SEPT11 · SEP11_HUMAN · IPI00019376 · Q9NVA2)⌘
H. sapiensENSEMBL:ENSG00000140623 · UniProtKB:Q8IYM1 (Septin-12 · SEP12_HUMAN · IPI00745407 · IPI00293544 · SEPT12 · Q8IYM1)⌘
H. sapiensENSEMBL:ENSG00000214765 · UniProtKB:A8MT51 (SEPT7B · A8MT51 · IPI00900357 · IPI00900267 · SEP13_HUMAN · SEPT13 · Septin-13 · IPI00900320)⌘
H. sapiensUniProtKB:Q6ZU15 (IPI00248126 · Septin-14 · SEPT14 · SEP14_HUMAN · Q6ZU15) · ENSEMBL:ENSG00000154997⌘
H. sapiensENSEMBL:ENSG00000180096 · UniProtKB:Q8WYJ6 (Q8WYJ6 · DIFF6 · IPI00657797 · SEPT1_HUMAN · SEPT1 · Septin-1 · PNUTL3)⌘
H. sapiensENSEMBL:ENSG00000168385 · UniProtKB:Q15019 (SEPT2_HUMAN · IPI00014177 · KIAA0158 · Septin-2 · NEDD5 · DIFF6 · SEPT2 · Q15019)⌘
H. sapiensENSEMBL:ENSG00000100167 · UniProtKB:Q9UH03 (SEPT3_HUMAN · IPI00384187 · SEPT3 · IPI00745056 · Q9UH03 · SEP3 · IPI00022652)Neuronal-specific septin-3⌘
H. sapiensENSEMBL:ENSG00000108387 · UniProtKB:O43236 (hucep-7 · O43236 · SEPT4_HUMAN · IPI00183878 · IPI00011589 · SEPT4 · Septin-4 · PNUTL2)⌘
H. sapiensENSEMBL:ENSG00000184702 · UniProtKB:Q99719 (Septin-5 · PNUTL1 · Q99719 · IPI00017731 · SEPT5_HUMAN · SEPT5)⌘
H. sapiensENSEMBL:ENSG00000125354 · UniProtKB:Q14141 (SEP2 · IPI00376992 · IPI00550119 · Septin-6 · SEPT6_HUMAN · IPI00744597 · Q14141 · SEPT6 · KIAA0128 · IPI00216139)⌘
H. sapiensENSEMBL:ENSG00000122545 · UniProtKB:Q16181 (SEPT7_HUMAN · Septin-7 · CDC10 · IPI00816201 · IPI00033025 · SEPT7 · Q16181)⌘
H. sapiensENSEMBL:ENSG00000164402 · UniProtKB:Q92599 (IPI00022082 · KIAA0202 · Septin-8 · IPI00787280 · Q92599 · SEPT8_HUMAN · SEPT8 · IPI00549434)⌘
H. sapiensENSEMBL:ENSG00000184640 · UniProtKB:Q9UHD8 (SEPT9 · SEPT9_HUMAN · KIAA0991 · Septin-9 · MSF · Q9UHD8)⌘
M. musculusNCBI:NP_081945 · MGI:MGI:1918339 (Sept12)septin 12⌘
M. musculusUniProtKB:Q8C650 · MGI:MGI:1918110 (Sept10)septin 10⌘
M. musculusUniProtKB:Q8C1B7 · MGI:MGI:1277214 (D5Ertd606e · Sept11)septin 11⌘
M. musculusUniProtKB:Q9DA97 · MGI:MGI:1921472 (Sept14)septin 14⌘
M. musculusUniProtKB:P42209 · MGI:MGI:1858916 (Sept1 · Diff6 · PNUTL3)septin 1⌘
M. musculusUniProtKB:P42208 · MGI:MGI:97298 (Sept2 · Nedd5)septin 2⌘
M. musculusUniProtKB:Q9Z1S5 · MGI:MGI:1345148 (Sep3 · Sept3)septin 3⌘
M. musculusUniProtKB:Q9Z2Q6 · MGI:MGI:1195461 (Pnutl1 · Cdcrel1 · Sept5)septin 5⌘
M. musculusUniProtKB:Q9R1T4 · MGI:MGI:1888939 (Sept6)septin 6⌘
M. musculusUniProtKB:O55131 · MGI:MGI:1335094 (Sept7 · Cdc10)septin 7⌘
M. musculusUniProtKB:Q8CHH9 · MGI:MGI:894310 (Sept8 · Sepl)septin 8⌘
M. musculusUniProtKB:Q80UG5 · MGI:MGI:1858222 (Sept9 · PNUTL4 · Sint1 · Msf · MSF1)septin 9 · SL3-3 integration site 1⌘
M. musculusUniProtKB:Q5ND16 · MGI:MGI:3651136 (OTTMUSG00000001265)predicted gene, OTTMUSG00000001265⌘
R. norvegicusNCBI:XP_001074044 · RGD:1308449 (Sept8)septin 8⌘
R. norvegicusNCBI:XP_001077761 · RGD:1585082 (Sept6)septin 6⌘
R. norvegicusNCBI:XP_001069593 · RGD:1596186 (Sept14)septin 14⌘
R. norvegicusNCBI:XP_001078429 · RGD:1585395
R. norvegicusNCBI:NP_001100678 · RGD:1307405 (Sept11)septin 11⌘
R. norvegicusUniProtKB:Q5PQK1 · RGD:1359307 (Sept10)septin 10⌘
R. norvegicusUniProtKB:Q4V8G5 · RGD:1565511 (Sept12)septin 12⌘
R. norvegicusUniProtKB:Q91Y81 · RGD:620056 (Sept2)septin 2⌘
R. norvegicusRGD:621745 (Sept3) · UniProtKB:Q9WU34 (IPI00203347 · IPI00203344 · Q9WU34 · SEPT3_RAT · Sept3 · IPI00845881)septin 3 · Neuronal-specific septin-3⌘⌘
R. norvegicusUniProtKB:Q9JJM9 (Q9JJM9 · Pnutl1 · Septin-5 · SEPT5_RAT · IPI00201737 · IPI00655290 · Sept5 · IPI00559449) · RGD:621763 (Sept5)septin 5⌘⌘
R. norvegicusUniProtKB:Q9WVC0 · RGD:620469 (Sept7)septin 7⌘
R. norvegicusUniProtKB:Q9QZR6 (Sept9 · IPI00896129 · Septin-9 · IPI00655333 · IPI00194218 · IPI00782707 · Q9QZR6 · SEPT9_RAT) · RGD:708523 (Sept9)septin 9⌘⌘
R. norvegicusUniProtKB:Q5EB96 · RGD:1307216 (Sept1)septin 1⌘
R. norvegicusUniProtKB:Q6XUZ7 · RGD:1308781 (Sept4)septin 4⌘
S. cerevisiaeUniProtKB:P25342 · SGD:S000000595 (YCR002C · CDC10)Component of the septin ring of the mother-bud neck that is required for cytokinesis⌘
S. cerevisiaeUniProtKB:P32458 · SGD:S000003837 (YJR076C · CDC11 · PSL9)Component of the septin ring of the mother-bud neck that is required for cytokinesis⌘
S. cerevisiaeUniProtKB:P32468 · SGD:S000001149 (CLA10 · PSL7 · YHR107C · CDC12)Component of the septin ring of the mother-bud neck that is required for cytokinesis⌘
S. cerevisiaeUniProtKB:P32457 · SGD:S000004306 (YLR314C · CDC3)Component of the septin ring of the mother-bud neck that is required for cytokinesis⌘
S. cerevisiaeUniProtKB:Q07657 · SGD:S000002384 (YDL225W · SEP7 · SHS1)One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis⌘
S. cerevisiaeUniProtKB:Q04921 · SGD:S000002626 (YDR218C · SPR28)Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes⌘
S. cerevisiaeUniProtKB:P41901 · SGD:S000003291 (SPR3 · YGR059W)Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes⌘
S. pombeUniProtKB:O36023 · GeneDB_Spombe:SPAC4F10.11 (SPAC4F10.11 · spn1)septin Spn1⌘
S. pombeUniProtKB:Q09116 · GeneDB_Spombe:SPAC821.06 (spn2 · SPAC821.06)septin Spn2⌘
S. pombeUniProtKB:P48008 · GeneDB_Spombe:SPBC16A3.01 (SPBC543.01c · SPBC16A3.01 · spn3)septin Spn3⌘
S. pombeUniProtKB:P48009 · GeneDB_Spombe:SPAC9G1.11c (spn4 · SPAC9G1.11c)septin Spn4⌘
S. pombeUniProtKB:P48010 · GeneDB_Spombe:SPAC24C9.15c (meu28 · SPAC24C9.15c · spn5 · mde9)septin Spn5⌘
S. pombeUniProtKB:Q09883 · GeneDB_Spombe:SPCC188.12 (spn6 · SPCC584.09 · SPCC188.12)septin Spn6⌘
S. pombeUniProtKB:O60165 · GeneDB_Spombe:SPBC19F8.01c (SPBC21.08c · SPBC19F8.01c · mde8 · spn7)septin Spn7⌘
ProteinPublicationCurator Notes
UniProtKB:P25342 · SGD:S000000595PMID:24055994 Horowitz A, et al. The human septin7 and the yeast CDC10 septin prevent Bax and copper mediated cell death in yeast. Biochim Biophys Acta. 2013 Dec;1833(12):3186-94.The H. sapiens protein 7-Sep complements a homologous mutation in S. cerevisiae.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000184640 · UniProtKB:Q9UHD8#162100 AMYOTROPHY, HEREDITARY NEURALGIC; HNA;;NEURITIS WITH BRACHIAL PREDILECTION; NAPB;;BRACHIAL PLEXUS NEUROPATHY, HEREDITARY;;AMYOTROPHY, HEREDITARY NEURALGIC, WITH PREDILECTION FOR BRACHIAL PLEXUS
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu