This family has 99 members: 3 Arabidopsis thaliana, 4 Caenorhabditis elegans, 18 Danio rerio, 1 Dictyostelium discoideum, 4 Drosophila melanogaster, 13 Gallus gallus, 16 Homo sapiens, 16 Mus musculus, 17 Rattus norvegicus, 3 Saccharomyces cerevisiae, 4 Schizosaccharomyces pombe.
Interactive Java Applets: Notung Tree Analysis · Jalview Alignment
| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | NCBI:NP_196232.1 · TAIR:locus:2152850 (K16F4_11 · AT5G06140 · K16F4.11 · ATSNX1 · SNX1) | ARABIDOPSIS THALIANA SORTING NEXIN 1 · SORTING NEXIN 1 |  |
| A. thaliana | NCBI:NP_200652.2 · TAIR:locus:2171218 (AT5G58440 · SNX2a · MQJ2.4 · MQJ2_4) | SORTING NEXIN 2a | |
| A. thaliana | NCBI:NP_196329.2 · TAIR:locus:2182880 (T28J14.60 · SNX2b · T28J14_60 · AT5G07120) | SORTING NEXIN 2b | |
| C. elegans | WB:WBGene00004927 (snx-1 · C05D9.1) · UniProtKB:Q9GYJ9 (snx-1 · C05D9.1) | Sorting nexin protein 1 | |
| C. elegans | WB:WBGene00013354 (Y59A8B.22) · UniProtKB:Q9NES0 (Y59A8B.22) | Protein Y59A8B.22, partially confirmed by transcript evidence | |
| C. elegans | WB:WBGene00006503 (W06D4.5 · snx-3) · UniProtKB:Q9XW41 | | |
| C. elegans | WB:WBGene00003086 (Y37A1B.2 · lst-4) · UniProtKB:Q9XXG2 | | |
| D. rerio | ENSEMBL:ENSDARP00000059238 | ||
| D. rerio | ENSEMBL:ENSDARP00000088752 | ||
| D. rerio | ENSEMBL:ENSDARP00000088296 | ||
| D. rerio | UniProtKB:Q566W7 · ZFIN:ZDB-GENE-050417-330 (snx30) | sorting nexin family member 30 | |
| D. rerio | ENSEMBL:ENSDARG00000052522 · UniProtKB:Q1ED00 | ||
| D. rerio | UniProtKB:Q1L8B9 · ENSEMBL:ENSDARG00000058061 | ||
| D. rerio | UniProtKB:Q3B7E7 · ZFIN:ZDB-GENE-030131-921 (snx3) | sorting nexin 3 | |
| D. rerio | UniProtKB:Q4VA89 · ZFIN:ZDB-GENE-050913-152 (snx6) | sorting nexin 6 | |
| D. rerio | UniProtKB:Q58EC1 · ZFIN:ZDB-GENE-030131-1923 (snx4) | sorting nexin 4 | |
| D. rerio | ENSEMBL:ENSDARG00000044246 · UniProtKB:Q5DTD0 | ||
| D. rerio | UniProtKB:Q5SPP1 · ZFIN:ZDB-GENE-031118-50 (snx9l) | sorting nexin 9-like | |
| D. rerio | ZFIN:ZDB-GENE-040704-77 (zgc:92458) · UniProtKB:Q6GMJ0 | | |
| D. rerio | ENSEMBL:ENSDARG00000004405 · UniProtKB:Q7SXF9 | ||
| D. rerio | UniProtKB:Q7ZZB1 · ZFIN:ZDB-GENE-030616-66 (snx9) | sorting nexin 9 | |
| D. rerio | UniProtKB:Q803J1 · ZFIN:ZDB-GENE-040426-787 (snx12) | sorting nexin 12 | |
| D. rerio | UniProtKB:A7E289 · ZFIN:ZDB-GENE-060302-3 (snx1) | sorting nexin 1 | |
| D. rerio | UniProtKB:Q58EF8 · ZFIN:ZDB-GENE-041111-209 (snx33) | sorting nexin 33 | |
| D. rerio | UniProtKB:Q803H8 · ZFIN:ZDB-GENE-040426-2857 (snx5) | sorting nexin 5 | |
| D. discoideum | UniProtKB:Q86IF6 · dictyBase:DDB_G0272989 (vps5) | putative sorting nexin, Phox domain-containing protein | |
| D. melanogaster | FB:FBgn0040475 (p63 · SH3PX1 · CG6757 · DSH3PX · DSH3PX1) · UniProtKB:Q9NCC3 | | |
| D. melanogaster | FB:FBgn0038065 (CG6359) · UniProtKB:Q9VG51 | | |
| D. melanogaster | FB:FBgn0032005 (Snx6 · CG8282 · Dsnx6) · UniProtKB:Q9VLQ9 | | |
| D. melanogaster | FB:FBgn0031534 (CG2774) · UniProtKB:Q9VQQ6 | | |
| G. gallus | NCBI:XP_001231594 · ENTREZ:768969 | ||
| G. gallus | NCBI:XP_414774 · ENTREZ:416468 | ||
| G. gallus | NCBI:XP_422321 · ENTREZ:424478 | ||
| G. gallus | NCBI:XP_424910 · ENTREZ:427330 | ||
| G. gallus | NCBI:XP_422107 · ENTREZ:424260 | ||
| G. gallus | NCBI:XP_419693 · ENTREZ:421654 | ||
| G. gallus | NCBI:XP_425052 · ENTREZ:427480 | ||
| G. gallus | UniProtKB:Q5F406 (Q5F406 · RCJMB04_3o14 · IPI00578377) · ENTREZ:426797 | | |
| G. gallus | UniProtKB:Q5ZHT0 (RCJMB04_33j6 · Q5ZHT0 · IPI00575249) · ENTREZ:428704 | | |
| G. gallus | UniProtKB:Q5ZHT2 (IPI00589513 · RCJMB04_33i8 · Q5ZHT2) · ENTREZ:416718 | | |
| G. gallus | UniProtKB:Q5ZIA3 (IPI00596138 · RCJMB04_28m8 · Q5ZIA3) · ENTREZ:421772 | | |
| G. gallus | UniProtKB:Q5ZIF9 (Q5ZIF9 · IPI00598512 · RCJMB04_26n19) · ENTREZ:420628 | | |
| G. gallus | UniProtKB:Q5ZK22 (RCJMB04_13l2 · IPI00579310 · Q5ZK22) · ENTREZ:771038 | | |
| H. sapiens | ENSEMBL:ENSG00000086300 · UniProtKB:Q9Y5X0 (SNX10 · SNX10_HUMAN · IPI00916501 · Q9Y5X0) | Sorting nexin-10 | |
| H. sapiens | ENSEMBL:ENSG00000002919 · UniProtKB:Q9Y5W9 (Q9Y5W9 · SNX11_HUMAN · SNX11 · IPI00001867) | Sorting nexin-11 | |
| H. sapiens | ENSEMBL:ENSG00000147164 · UniProtKB:Q9UMY4 (IPI00438170 · Q9UMY4 · SNX12_HUMAN · IPI00844112 · SNX12) | Sorting nexin-12 | |
| H. sapiens | ENSEMBL:ENSG00000178996 · UniProtKB:Q96RF0 (SNAG1 · SH3PXD3B · IPI00657938 · IPI00045219 · SNX18 · Q96RF0 · SNX18_HUMAN) | Sorting nexin-18 | |
| H. sapiens | ENSEMBL:ENSG00000028528 · UniProtKB:Q13596 (IPI00183530 · Q13596 · SNX1_HUMAN · IPI00220527 · SNX1) | Sorting nexin-1 | |
| H. sapiens | ENSEMBL:ENSG00000205302 · UniProtKB:O60749 (IPI00299095 · TRG9 · SNX2 · SNX2_HUMAN · O60749) | Sorting nexin-2 | |
| H. sapiens | ENSEMBL:ENSG00000148158 · UniProtKB:Q5VWJ9 (SNX30 · IPI00855946 · Q5VWJ9 · SNX30_HUMAN) | Sorting nexin-30 | |
| H. sapiens | ENSEMBL:ENSG00000172803 · UniProtKB:Q86XE0 (IPI00885014 · Q86XE0 · IPI00396025 · SNX32_HUMAN · SNX6B · SNX32) | Sorting nexin-32 | |
| H. sapiens | ENSEMBL:ENSG00000173548 · UniProtKB:Q8WV41 (SNX30 · IPI00103013 · SNX33 · Q8WV41 · SNX33_HUMAN · SH3PX3 · SH3PXD3C) | Sorting nexin-33 | |
| H. sapiens | ENSEMBL:ENSG00000112335 · UniProtKB:O60493 (IPI00029740 · IPI00552276 · IPI00815770 · SNX3_HUMAN · SNX3 · O60493 · IPI00216508) | Sorting nexin-3 | |
| H. sapiens | ENSEMBL:ENSG00000114520 · UniProtKB:O95219 (SNX4_HUMAN · IPI00029403 · O95219 · SNX4) | Sorting nexin-4 | |
| H. sapiens | ENSEMBL:ENSG00000089006 · UniProtKB:Q9Y5X3 (IPI00295209 · SNX5_HUMAN · Q9Y5X3 · SNX5) | Sorting nexin-5 | |
| H. sapiens | ENSEMBL:ENSG00000129515 · UniProtKB:Q9UNH7 (SNX6_HUMAN · IPI00298111 · SNX6 · Q9UNH7) | Sorting nexin-6 | |
| H. sapiens | ENSEMBL:ENSG00000162627 · UniProtKB:Q9UNH6 (SNX7 · SNX7_HUMAN · IPI00216576 · Q9UNH6 · IPI00009203) | Sorting nexin-7 | |
| H. sapiens | ENSEMBL:ENSG00000106266 · UniProtKB:Q9Y5X2 (SNX8_HUMAN · Q9Y5X2 · IPI00001885 · SNX8) | Sorting nexin-8 | |
| H. sapiens | ENSEMBL:ENSG00000130340 · UniProtKB:Q9Y5X1 (SNX9 · SNX9_HUMAN · SH3PX1 · Q9Y5X1 · SH3PXD3A · IPI00001883) | Sorting nexin-9 | |
| M. musculus | UniProtKB:Q9CWT3 · MGI:MGI:1919232 (Snx10) | sorting nexin 10 | |
| M. musculus | UniProtKB:Q91WL6 · MGI:MGI:1921729 (Snx11) | sorting nexin 11 | |
| M. musculus | UniProtKB:O70493 · MGI:MGI:1919331 (Snx12) | sorting nexin 12 | |
| M. musculus | UniProtKB:Q91ZR2 · MGI:MGI:2137642 (Snag1 · Snx18) | sorting nexin 18 | |
| M. musculus | UniProtKB:Q9WV80 · MGI:MGI:1928395 (Snx1) | sorting nexin 1 | |
| M. musculus | UniProtKB:Q9CWK8 · MGI:MGI:1915054 (Snx2) | sorting nexin 2 | |
| M. musculus | UniProtKB:Q8CE50 · MGI:MGI:2443882 (Snx30) | sorting nexin family member 30 | |
| M. musculus | UniProtKB:Q80ZJ7 · MGI:MGI:2444704 (Snx6b · Snx32) | sorting nexin 32 | |
| M. musculus | UniProtKB:Q4VAA7 · MGI:MGI:2443239 (Sh3px3 · Snx33) | sorting nexin 33 | |
| M. musculus | UniProtKB:O70492 · MGI:MGI:1860188 (SDP3 · Snx3) | sorting nexin 3 | |
| M. musculus | UniProtKB:Q91YJ2 · MGI:MGI:1916400 (Snx4) | sorting nexin 4 | |
| M. musculus | UniProtKB:Q9D8U8 · MGI:MGI:1916428 (Snx5 · D2Ertd52e) | sorting nexin 5 | |
| M. musculus | UniProtKB:Q6P8X1 · MGI:MGI:1919433 (Snx6) | sorting nexin 6 | |
| M. musculus | UniProtKB:Q9CY18 · MGI:MGI:1923811 (Snx7) | sorting nexin 7 | |
| M. musculus | UniProtKB:Q8CFD4 · MGI:MGI:2443816 (Snx8) | sorting nexin 8 | |
| M. musculus | UniProtKB:Q91VH2 · MGI:MGI:1913866 (SH3PX1 · SDP1 · Snx9) | sorting nexin 9 | |
| R. norvegicus | NCBI:XP_226769 · RGD:1310367 (Snx18) | sorting nexin 18 | |
| R. norvegicus | NCBI:XP_001056835 · RGD:1311367 | ||
| R. norvegicus | NCBI:XP_001072295 · RGD:1309763 (Snx4) | sorting nexin 4 | |
| R. norvegicus | NCBI:XP_001067064 · RGD:1584466 (Snx9) | sorting nexin 9 | |
| R. norvegicus | NCBI:XP_001065004 · RGD:1305791 (Snx8) | sorting nexin 8 | |
| R. norvegicus | NCBI:XP_001073948 · RGD:1307898 (Snx33) | sorting nexin 33 | |
| R. norvegicus | NCBI:XP_001075611 · RGD:1304647 (Snx6) | sorting nexin 6 | |
| R. norvegicus | NCBI:XP_001073782 · RGD:1560591 | ||
| R. norvegicus | NCBI:XP_001053951 · RGD:1310190 (Snx5) | sorting nexin 5 | |
| R. norvegicus | NCBI:XP_343800 · RGD:1565585 (Snx12) | sorting nexin 12 | |
| R. norvegicus | NCBI:NP_001099605 · RGD:1310291 (Snx2) | sorting nexin 2 | |
| R. norvegicus | NCBI:XP_001062902 · RGD:1595295 (LOC682745) | similar to sorting nexin 11 | |
| R. norvegicus | UniProtKB:Q99N27 · RGD:68935 (Snx1) | sorting nexin 1 | |
| R. norvegicus | UniProtKB:Q5U211 · RGD:1595151 (LOC684097) | similar to sorting nexin 3 | |
| R. norvegicus | UniProtKB:Q5BJX4 · RGD:1305782 (Snx10) | sorting nexin 10 | |
| R. norvegicus | UniProtKB:Q5RJQ6 · RGD:1307319 (Snx11) | sorting nexin 11 | |
| R. norvegicus | UniProtKB:Q66H41 · RGD:1305480 (Snx7) | sorting nexin 7 | |
| S. cerevisiae | UniProtKB:Q08826 · SGD:S000005884 (YOR357C · SNX3 · GRD19) | Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment | |
| S. cerevisiae | UniProtKB:P47057 · SGD:S000003573 (YJL036W · ATG24 · CVT13 · SNX4) | Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport | |
| S. cerevisiae | UniProtKB:Q92331 · SGD:S000005595 (VPT5 · YOR069W · GRD2 · PEP10 · YOR29-20 · VPS5) | Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus | |
| S. pombe | UniProtKB:O94291 · GeneDB_Spombe:SPBC887.06c (snx3 · grd19 · SPBC887.06c) | sorting nexin Snx3 | |
| S. pombe | UniProtKB:O14243 · GeneDB_Spombe:SPAC6F6.12 (SPAC6F6.12) | autophagy associated protein Atg24 | |
| S. pombe | UniProtKB:Q9C0U7 · GeneDB_Spombe:SPCPJ732.01 (vps5 · SPCPJ732.01) | retromer complex subunit Vps5 | |
| S. pombe | UniProtKB:Q9P779 · GeneDB_Spombe:SPBC1711.11 (SPBC1711.11) | autophagy associated protein | |
No functional conservation results.
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |
| OMIM (1) | |
|---|---|
| ENSEMBL:ENSG00000112335 · UniProtKB:O60493 | #601349 MICROPHTHALMIA, SYNDROMIC 8; MCOPS8;;MICROCEPHALY, MICROPHTHALMIA, ECTRODACTYLY OF LOWER LIMBS, AND PROGNATHISM;MMEP |