This family has 18 members: 6 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 3 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
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18 members.| Organism | Protein (Synonyms) | Description | AmiGO |
|---|
| A. thaliana | NCBI:NP_188871.1 · TAIR:locus:2087842 (RPB5A · AT3G22320 · NRPB5 · ATRPABC24.3 · MCB17.20 · NRPD5) | RNA POLYMERASE II FIFTH LARGEST SUBUNIT, A |  |
| A. thaliana | NCBI:NP_181665.1 · TAIR:locus:2040257 (F13H10.11 · RPB5D · F13H10_11 · AT2G41340) | RNA POLYMERASE II FIFTH LARGEST SUBUNIT, D | |
| A. thaliana | NCBI:NP_191267.1 · TAIR:locus:2080650 (NRPE5 · AT3G57080 · F24I3.160 · RPB5B) | RNA POLYMERASE II FIFTH LARGEST SUBUNIT, B | |
| A. thaliana | NCBI:NP_191013.1 · TAIR:locus:2096971 (AT3G54490 · T14E10.60 · RPB5E) | RNA POLYMERASE II FIFTH LARGEST SUBUNIT, E | |
| A. thaliana | NCBI:NP_188290.1 · TAIR:locus:2089338 | | |
| A. thaliana | NCBI:NP_200606.1 · TAIR:locus:2174388 (MTI20_24 · MTI20.24 · RPB5C · AT5G57980) | RNA POLYMERASE II FIFTH LARGEST SUBUNIT, C | |
| C. elegans | WB:WBGene00019246 (rpb-5 · H27M09.2) · UniProtKB:Q9N5K2 | | |
| D. rerio | UniProtKB:Q6DEG5 · ZFIN:ZDB-GENE-040801-83 (polr2e) | polymerase (RNA) II (DNA directed) polypeptide E | |
| D. discoideum | NCBI:EAL61802.1 · dictyBase:DDB_G0291636 (rpb5) | RNA polymerase II core subunit, RNA polymerase I core subunit, RNA polymerase III core subunit | |
| D. melanogaster | FB:FBgn0033571 (RPB5 · DmRPB5 · CG11979 · Rpb5) · UniProtKB:Q7JZF5 | | |
| G. gallus | NCBI:XP_418224 · ENTREZ:420103 | | |
| H. sapiens | ENSEMBL:ENSG00000099817 · UniProtKB:P19388 (RPAB1_HUMAN · POLR2E · IPI00291093 · P19388) | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | |
| M. musculus | UniProtKB:Q80UW8 · MGI:MGI:1913670 (XAP4 · RPB5 · 25kDa · Polr2e) | polymerase (RNA) II (DNA directed) polypeptide E | |
| R. norvegicus | NCBI:XP_001076333 · RGD:1589817 (Polr2e) | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | |
| R. norvegicus | NCBI:XP_216839 · RGD:1305418 | | |
| R. norvegicus | NCBI:XP_001076884 · RGD:1590114 | | |
| S. cerevisiae | UniProtKB:P20434 · SGD:S000000358 (RPB5 · YBR154C) | RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III | |
| S. pombe | UniProtKB:Q09191 · GeneDB_Spombe:SPAC23C4.15 (rpb5 · SPAC23C4.15) | DNA-directed RNA polymerase I, II and III subunit Rpb5 | |
| Protein | Publication | Curator Notes | |
|---|
| UniProtKB:P20434 · SGD:S000000358 |  7651387 Shpakovski GV, et al. Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. Mol Cell Biol. 1995 Sep;15(9):4702-10. | The H. sapiens protein P19388 does not complement a homologous mutation in S. cerevisiae. Human hsRPB5 (P19388) does not complement a yeast rpb5 null mutant. |
| UniProtKB:P20434 · SGD:S000000358 | 8524256 McKune K, et al. Six human RNA polymerase subunits functionally substitute for their yeast counterparts. Mol Cell Biol. 1995 Dec;15(12):6895-900. | The H. sapiens protein P19388 does not complement a homologous mutation in S. cerevisiae. Human hsRPB5 (P19388) did not complement a yeast rpb5 null mutant even when human hsRPB5 was expressed on a high-copy-number plasmid. |
| UniProtKB:P20434 · SGD:S000000358 | 7651387 Shpakovski GV, et al. Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. Mol Cell Biol. 1995 Sep;15(9):4702-10. | The H. sapiens protein POLR2E does not complement a homologous mutation in S. cerevisiae. |
| UniProtKB:P20434 · SGD:S000000358 | 8524256 McKune K, et al. Six human RNA polymerase subunits functionally substitute for their yeast counterparts. Mol Cell Biol. 1995 Dec;15(12):6895-900. | The H. sapiens protein POLR2E does not complement a homologous mutation in S. cerevisiae. |