P-POD: Princeton Protein Orthology Database: GO3/Jaccard158

This family has 101 members: 9 Arabidopsis thaliana, 6 Caenorhabditis elegans, 18 Danio rerio, 1 Dictyostelium discoideum, 3 Drosophila melanogaster, 17 Gallus gallus, 15 Homo sapiens, 15 Mus musculus, 15 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Jaccard158
101 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaTAIR:locus:2099530 (T21L8.40 · AT3G47290) · NCBI:NP_190313.1⌘
A. thalianaNCBI:NP_850327.2 · TAIR:locus:504956034 (AT2G40116)⌘
A. thalianaNCBI:NP_568881.1 · TAIR:locus:2178803 (MZN1_12 · PLC1 · ATPLC · ATPLC1 · MZN1.12 · AT5G58670)PHOSPHOLIPASE C · ARABIDOPSIS THALIANA PHOSPHOLIPASE C · PHOSPHOLIPASE C 1 · ARABIDOPSIS THALIANA PHOSPHOLIPASE C 1⌘
A. thalianaNCBI:NP_191153.1 · TAIR:locus:2082018 (F27K19.120 · AT3G55940)⌘
A. thalianaNCBI:NP_190306.2 · TAIR:locus:2075696 (F13I12.270 · AT3G47220)⌘
A. thalianaNCBI:NP_200677.2 · TAIR:locus:2178833 (AT5G58690 · MZN1_15 · MZN1.15)⌘
A. thalianaNCBI:NP_200678.2 · TAIR:locus:2178848 (MZN1_19 · AT5G58700 · MZN1.19)⌘
A. thalianaNCBI:NP_187464.1 · TAIR:locus:2103437 (AT3G08510 · T8G24.4 · ATPLC2)PHOSPHOLIPASE C 2⌘
A. thalianaNCBI:NP_195565.2 · TAIR:locus:2121239 (AT4G38530 · ATPLC1)ARABIDOPSIS THALIANA PHOSPHOLIPASE C 1⌘
C. elegansWB:WBGene00004039 (plc-4 · R05G6.8) · UniProtKB:Q21754⌘
C. elegansWB:WBGene00004038 (plc-3 · T01E8.3) · UniProtKB:Q22070⌘
C. elegansWB:WBGene00004045 (K10F12.3 · pll-1) · UniProtKB:Q8IA75⌘
C. elegansWB:WBGene00001177 (egl-8 · B0348.4) · UniProtKB:Q95X29⌘
C. elegansWB:WBGene00004036 (F31B12.1 · plc-1) · UniProtKB:Q9TVI2⌘
C. elegansWB:WBGene00004037 (Y75B12B.6 · plc-2) · UniProtKB:Q9XWB7⌘
D. rerioENSEMBL:ENSDARP00000080582
D. rerioENSEMBL:ENSDARP00000076578
D. rerioENSEMBL:ENSDARP00000073784
D. rerioENSEMBL:ENSDARP00000074246
D. rerioENSEMBL:ENSDARP00000059592
D. rerioENSEMBL:ENSDARP00000057622
D. rerioENSEMBL:ENSDARP00000004276
D. rerioENSEMBL:ENSDARP00000090042
D. rerioENSEMBL:ENSDARP00000085109
D. rerioENSEMBL:ENSDARP00000006804
D. rerioENSEMBL:ENSDARG00000052957 · UniProtKB:A5D6R3
D. rerioUniProtKB:Q1LWH7 · ZFIN:ZDB-GENE-050208-654 (plcd4a)phospholipase C, delta 4a⌘
D. rerioUniProtKB:Q1LWV8 · ZFIN:ZDB-GENE-030131-9532 (plcg2)phospholipase C, gamma 2⌘
D. rerioENSEMBL:ENSDARG00000068763 · UniProtKB:Q1LWW0
D. rerioENSEMBL:ENSDARG00000057954 · UniProtKB:Q1LWW2
D. rerioUniProtKB:Q7ZU40 · ZFIN:ZDB-GENE-030131-9435 (plcd1b)phospholipase C, delta 1b⌘
D. rerioUniProtKB:Q7ZZ38 · ZFIN:ZDB-GENE-030616-594 (plcb3)phospholipase C, beta 3 (phosphatidylinositol-specific)⌘
D. rerioUniProtKB:Q804J6 · ZFIN:ZDB-GENE-030421-3 (plcg1)phospholipase C, gamma 1⌘
D. discoideumUniProtKB:Q02158 · dictyBase:DDB_G0292736 (DdPLC · plc · pipA)phosphoinositide-specific phospholipase C⌘
D. melanogasterUniProtKB:P25455 · FB:FBgn0004611 (Plc21C · PLC21C · plc21 · plc-21 · PLC[[Beta]] · CG4574 · PLC-21C · PLC · PLC-21 · Plc&abr;21C)Phospholipase C at 21C⌘
D. melanogasterUniProtKB:P13217 · FB:FBgn0004625 (no-receptor-potential-A · anon-EST:Posey221 · x13 · PLCbeta · DIP2 · x24 · nofC · CdkA · norpA · phospholipase-C · rof · x12 · CG3620 · PLC-beta · x16 · PI-PLC · PLC · NorpA · NORPA)phospholipase C · Phospholipase C-beta · Norp A · no receptor potential · no receptor potential A · phospholipase C-beta · no receptor potentials A⌘
D. melanogasterUniProtKB:Q9VXH3 · FB:FBgn0003416 (PLC-gammaD · plc-gammad · PLCgammaDmel · PLC-gamma · sl · Plcgamma · CG4200 · PLCgamma · p145 · PLC)phospholipase Cgamma · Phospholipase C gamma · PLC-gamma D · small wing · phospholipase C gamma · Small wing⌘
G. gallusNCBI:XP_001231684 · ENTREZ:416730
G. gallusNCBI:XP_001236839 · ENTREZ:777381
G. gallusNCBI:XP_422832 · ENTREZ:425030
G. gallusNCBI:XP_421916 · ENTREZ:424060
G. gallusNCBI:XP_418522 · ENTREZ:420416
G. gallusNCBI:XP_001233460 · ENTREZ:770139
G. gallusNCBI:XP_418744 · ENTREZ:420645
G. gallusNCBI:XP_418151 · ENTREZ:420029
G. gallusNCBI:XP_426830 · ENTREZ:429273
G. gallusNCBI:XP_422063 · ENTREZ:424214
G. gallusNCBI:XP_001235455 · ENTREZ:772298
G. gallusNCBI:XP_425738 · ENTREZ:428180
G. gallusNCBI:XP_414166 · ENTREZ:415805
G. gallusNCBI:XP_429034 · ENTREZ:431481
G. gallusNCBI:XP_420945 · ENTREZ:423014
G. gallusNCBI:XP_425261 · ENTREZ:427687
G. gallusENTREZ:418182 · UniProtKB:Q2VRL0 (PLCZ1 · PLCZ1_CHICK · Q2VRL0 · IPI00589297)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1⌘
H. sapiensENSEMBL:ENSG00000182621 · UniProtKB:Q9NQ66 (IPI00219563 · PLCB1_HUMAN · KIAA0581 · PLCB1 · Q9NQ66 · IPI00395561)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1⌘
H. sapiensENSEMBL:ENSG00000137841 · UniProtKB:Q00722 (PLCB2_HUMAN · Q00722 · IPI00784327 · IPI00914935 · PLCB2)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2⌘
H. sapiensENSEMBL:ENSG00000149782 · UniProtKB:Q01970 (PLCB3 · PLCB3_HUMAN · IPI00010400 · Q01970)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3⌘
H. sapiensENSEMBL:ENSG00000101333 · UniProtKB:Q15147 (IPI00883983 · PLCB4_HUMAN · IPI00014897 · PLCB4 · Q15147)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4⌘
H. sapiensENSEMBL:ENSG00000187091 · UniProtKB:P51178 (PLCD1 · IPI00746030 · P51178 · PLCD1_HUMAN)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1⌘
H. sapiensENSEMBL:ENSG00000161714 · UniProtKB:Q8N3E9 (PLCD3_HUMAN · IPI00152701 · PLCD3 · Q8N3E9 · KIAA1964)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3⌘
H. sapiensENSEMBL:ENSG00000115556 · UniProtKB:Q9BRC7 (PLCD4 · IPI00013745 · Q9BRC7 · IPI00867639 · PLCD4_HUMAN)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4⌘
H. sapiensENSEMBL:ENSG00000138193 · UniProtKB:Q9P212 (PLCE1_HUMAN · IPI00010604 · KIAA1516 · PLCE1 · IPI00791109 · PPLC · PLCE · Q9P212)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1⌘
H. sapiensENSEMBL:ENSG00000124181 · UniProtKB:P19174 (PLCG1_HUMAN · PLC1 · IPI00016736 · PLCG1 · P19174)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1⌘
H. sapiensENSEMBL:ENSG00000197943 · UniProtKB:P16885 (PLCG2 · PLCG2_HUMAN · IPI00329185 · P16885)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2⌘
H. sapiensENSEMBL:ENSG00000114805 · UniProtKB:Q4KWH8 (Q4KWH8 · IPI00175416 · KIAA1069 · PLCH1 · IPI00848061 · PLCL3 · PLCH1_HUMAN · IPI00783616 · IPI00889624)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1⌘
H. sapiensENSEMBL:ENSG00000149527 · UniProtKB:O75038 (IPI00409676 · IPI00744887 · PLCH2_HUMAN · PLCL4 · IPI00654552 · IPI00873071 · PLCH2 · KIAA0450 · O75038 · IPI00384764)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2⌘
H. sapiensENSEMBL:ENSG00000115896 · UniProtKB:Q15111 (Q15111 · IPI00006660 · PLCL1_HUMAN · IPI00789181 · PLCL1)Inactive phospholipase C-like protein 1⌘
H. sapiensENSEMBL:ENSG00000154822 · UniProtKB:Q9UPR0 (PLCE2 · KIAA1092 · PLCL2_HUMAN · IPI00010334 · IPI00789859 · IPI00847504 · Q9UPR0 · PLCL2)Inactive phospholipase C-like protein 2⌘
H. sapiensENSEMBL:ENSG00000139151 · UniProtKB:Q86YW0 (IPI00793213 · PLCZ1 · Q86YW0 · PLCZ1_HUMAN · IPI00172666 · IPI00792324)1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1⌘
M. musculusNCBI:NP_038857 · MGI:MGI:107464 (Plcb4)phospholipase C, beta 4⌘
M. musculusUniProtKB:Q9Z1B3 · MGI:MGI:97613 (Plcb1)phospholipase C, beta 1⌘
M. musculusUniProtKB:A3KGF7 · MGI:MGI:107465 (Plcb2)phospholipase C, beta 2⌘
M. musculusUniProtKB:P51432 · MGI:MGI:104778 (Plcb3)phospholipase C, beta 3⌘
M. musculusUniProtKB:Q8R3B1 · MGI:MGI:97614 (Plcd1)PLC-delta 1 · phospholipase C, delta 1⌘
M. musculusUniProtKB:Q8K2J0 · MGI:MGI:107451 (Plcd3)phospholipase C, delta 3⌘
M. musculusUniProtKB:Q8K3R3 · MGI:MGI:107469 (Plcd4)phospholipase C, delta 4⌘
M. musculusUniProtKB:Q8K4S1 · MGI:MGI:1921305 (Plce1 · PLCepsilon)phospholipase C, epsilon 1⌘
M. musculusUniProtKB:Q62077 · MGI:MGI:97615 (Plc-gamma1 · Plc-1 · Plcg-1 · Plcg1 · Cded)phospholipase C, gamma 1⌘
M. musculusUniProtKB:Q8CIH5 · MGI:MGI:97616 (Plcg-2 · PLCgamma2 · Plcg2)phospholipase C, gamma 2⌘
M. musculusUniProtKB:Q4KWH5 · MGI:MGI:2683547 (Plcl3 · Plch1 · PLCeta1)phospholipase C, eta 1⌘
M. musculusUniProtKB:A2AP18 · MGI:MGI:2443078 (Plch2 · Plcl4 · PLCeta2)phospholipase C, eta 2⌘
M. musculusUniProtKB:Q3USB7 · MGI:MGI:3036262 (PRIP-1 · PLDL1 · PLC-L · Plcl1)phospholipase C-like 1⌘
M. musculusUniProtKB:Q8K394 · MGI:MGI:1352756 (PRIP-2 · Plcl2 · Plce2)phospholipase C-like 2⌘
M. musculusUniProtKB:Q8K4D7 · MGI:MGI:2150308 (Plcz1)phospholipase C, zeta 1⌘
R. norvegicusNCBI:XP_221004 · RGD:1310903 (Plcd3)phospholipase C, delta 3⌘
R. norvegicusNCBI:XP_217326 · RGD:1305941 (Plcl2)phospholipase C-like 2⌘
R. norvegicusNCBI:XP_001059231 · RGD:1561991 (Plch1)phospholipase C, eta 1⌘
R. norvegicusNCBI:XP_233728 · RGD:1304675 (Plch2)phospholipase C, eta 2⌘
R. norvegicusUniProtKB:P10687 · RGD:3344 (Plcb1)phospholipase C, beta 1 (phosphoinositide-specific)⌘
R. norvegicusUniProtKB:O89040 · RGD:621004 (Plcb2)phospholipase C, beta 2⌘
R. norvegicusUniProtKB:Q99JE6 · RGD:61993 (Plcb3)phospholipase C, beta 3 (phosphatidylinositol-specific)⌘
R. norvegicusRGD:3345 (Plcb4) · UniProtKB:Q9QW07 (IPI00231559 · IPI00211614 · PLCB4_RAT · IPI00231558 · Plcb4 · Q9QW07)phospholipase C, beta 4 · 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4⌘⌘
R. norvegicusUniProtKB:P10688 · RGD:3346 (Plcd1)phospholipase C, delta 1⌘
R. norvegicusRGD:621025 (Plcd4) · UniProtKB:Q62711 (IPI00867939 · IPI00210334 · Plcd4 · PLCD4_RAT · IPI00206026 · IPI00867935 · Q62711)phospholipase C, delta 4 · 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4⌘⌘
R. norvegicusUniProtKB:Q99P84 · RGD:69424 (Plce1)phospholipase C, epsilon 1⌘
R. norvegicusUniProtKB:P10686 · RGD:3347 (Plcg1)phospholipase C, gamma 1⌘
R. norvegicusUniProtKB:P24135 · RGD:3348 (Plcg2)phospholipase C, gamma 2⌘
R. norvegicusUniProtKB:Q62688 · RGD:708420 (Plcl1)phospholipase C-like 1⌘
R. norvegicusUniProtKB:Q5FX52 · RGD:1359567 (Plcz1)phospholipase C, zeta 1⌘
S. cerevisiaeUniProtKB:P32383 · SGD:S000006189 (PLC1 · YPL268W)Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG)⌘
S. pombeUniProtKB:P40977 · GeneDB_Spombe:SPAC22F8.11 (SPAC22F8.11 · plc1)phosphoinositide phospholipase C Plc1⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (1)
ENSEMBL:ENSG00000138193 · UniProtKB:Q9P212#610725 NEPHROTIC SYNDROME, TYPE 3; NPHS3;;NEPHROTIC SYNDROME, EARLY-ONSET, TYPE 3
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu