P-POD: Princeton Protein Orthology Database: GO3/Jaccard157

This family has 101 members: 12 Arabidopsis thaliana, 4 Caenorhabditis elegans, 14 Danio rerio, 12 Dictyostelium discoideum, 4 Drosophila melanogaster, 10 Gallus gallus, 11 Homo sapiens, 11 Mus musculus, 10 Rattus norvegicus, 7 Saccharomyces cerevisiae, 6 Schizosaccharomyces pombe.

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GO3/Jaccard157
101 members.
OrganismProtein (Synonyms)DescriptionAmiGO
A. thalianaNCBI:NP_194316.2 · TAIR:locus:2117532 (ORP4A · F14M19.140 · F14M19_140 · AT4G25860)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 4A⌘
A. thalianaNCBI:NP_187541.1 · TAIR:locus:2083594 (F3L24.17 · ORP3B · AT3G09300)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3B⌘
A. thalianaNCBI:NP_192983.2 · TAIR:locus:2135580 (T1P17_50 · T1P17.50 · ORP2B · AT4G12460)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 2B⌘
A. thalianaNCBI:NP_192558.2 · TAIR:locus:2132492 (AT4G08180 · T12G13.20 · ORP1C · T12G13_20)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1C⌘
A. thalianaNCBI:NP_195830.1 · TAIR:locus:2185163 (AT5G02100 · T7H20_150 · T7H20.150 · ORP3A · UNE18)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3A · UNFERTILIZED EMBRYO SAC 18⌘
A. thalianaNCBI:NP_172776.1 · TAIR:locus:2031910 (F3F19_19 · F3F19.19 · ORP1D · AT1G13170)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1D⌘
A. thalianaNCBI:NP_567732.1 · TAIR:locus:2117522 (AT4G25850 · ORP4B · F14M19.130 · F14M19_130)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 4B⌘
A. thalianaNCBI:NP_180660.1 · TAIR:locus:2052816 (AT2G31030 · ORP1B · F7F1_24 · F7F1.24)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1B⌘
A. thalianaNCBI:NP_200750.1 · TAIR:locus:2148368 (F2O15_17 · ORP3C · F2O15.17 · AT5G59420)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 3C⌘
A. thalianaNCBI:NP_200534.1 · TAIR:locus:2165575 (MJB24.5 · ORP4C · MJB24_5 · AT5G57240)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 4C⌘
A. thalianaNCBI:NP_180659.1 · TAIR:locus:2052801 (AT2G31020 · ORP1A · F7F1_23 · F7F1.23)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1A⌘
A. thalianaNCBI:NP_567662.1 · TAIR:locus:2127565 (AT4G22540 · F7K2.120 · F7K2_120 · ORP2A)OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 2A⌘
C. elegansWB:WBGene00012930 (Y47D3A.17 · obr-1) · UniProtKB:A7DTF2⌘
C. elegansWB:WBGene00016331 (obr-4 · C32F10.1) · UniProtKB:O01686⌘
C. elegansWB:WBGene00014215 (ZK1086.1 · obr-3) · UniProtKB:Q8MPR9⌘
C. elegansWB:WBGene00008832 (F14H8.1 · obr-2) · UniProtKB:Q93485⌘
D. rerioENSEMBL:ENSDARP00000070318
D. rerioENSEMBL:ENSDARP00000070006
D. rerioENSEMBL:ENSDARP00000058058
D. rerioENSEMBL:ENSDARP00000053613
D. rerioENSEMBL:ENSDARP00000087844
D. rerioENSEMBL:ENSDARP00000059249
D. rerioENSEMBL:ENSDARP00000012925
D. rerioENSEMBL:ENSDARP00000036494
D. rerioENSEMBL:ENSDARP00000074612
D. rerioUniProtKB:A0JMN8 · ZFIN:ZDB-GENE-061110-103 (osbpl9)oxysterol binding protein-like 9⌘
D. rerioENSEMBL:ENSDARG00000022772 · UniProtKB:A2BEG1
D. rerioUniProtKB:Q1LW95 · ZFIN:ZDB-GENE-040912-77 (osbpl3a)oxysterol binding protein-like 3a⌘
D. rerioUniProtKB:Q5XIY7 · ZFIN:ZDB-GENE-041010-212 (osbpl7)oxysterol binding protein-like 7⌘
D. rerioUniProtKB:Q7ZVL1 · ZFIN:ZDB-GENE-030131-6138 (osbpl2)oxysterol binding protein-like 2⌘
D. discoideumUniProtKB:Q54NM4 · dictyBase:DDB_G0285141 (osbJ)oxysterol binding family protein, member 10⌘
D. discoideumUniProtKB:Q54ID7 · dictyBase:DDB_G0288817 (osbK)oxysterol binding family protein, member 11⌘
D. discoideumUniProtKB:Q54EF5 · dictyBase:DDB_G0291562 (osbL)oxysterol binding family protein, member 12⌘
D. discoideumUniProtKB:Q8MPQ7 · dictyBase:DDB_G0280053 (osbA · OSBPa)oxysterol binding family protein, member 1⌘
D. discoideumUniProtKB:Q55CR3 · dictyBase:DDB_G0269938 (osbB)oxysterol binding family protein, member 2⌘
D. discoideumUniProtKB:Q55CR2 · dictyBase:DDB_G0269940 (osbC)oxysterol binding family protein, member 3⌘
D. discoideumUniProtKB:Q86KG4 · dictyBase:DDB_G0272498 (osbD)oxysterol binding family protein, member 4⌘
D. discoideumUniProtKB:Q86HL8 · dictyBase:DDB_G0274517 (osbE)oxysterol binding family protein, member 5⌘
D. discoideumUniProtKB:Q86HV4 · dictyBase:DDB_G0276427 (osbF)oxysterol binding family protein, member 6⌘
D. discoideumUniProtKB:Q54RM1 · dictyBase:DDB_G0283035 (osbG)oxysterol binding family protein, member 7⌘
D. discoideumUniProtKB:Q54QP6 · dictyBase:DDB_G0283709 (osbH · OSBPL6)oxysterol binding family protein, member 8⌘
D. discoideumUniProtKB:Q54PS9 · dictyBase:DDB_G0284353 (osbI)oxysterol binding family protein, member 9⌘
D. melanogasterFB:FBgn0033463 (CG1513) · UniProtKB:A1Z814⌘
D. melanogasterUniProtKB:O18397 · FB:FBgn0020626 (osbp · CG6708 · OSBP-Dm · Osbp)Oxysterol binding protein · Oxysterol Binding Protein · oxysterol binding protein⌘
D. melanogasterFB:FBgn0038786 (CG5077) · UniProtKB:Q9I7I8⌘
D. melanogasterFB:FBgn0034951 (CG3860) · UniProtKB:Q9W1D9⌘
G. gallusNCBI:XP_421982 · ENTREZ:424130
G. gallusNCBI:XP_425992 · ENTREZ:428432
G. gallusNCBI:XP_001234139 · ENTREZ:770816
G. gallusNCBI:XP_424206 · ENTREZ:426566
G. gallusNCBI:XP_415293 · ENTREZ:417002
G. gallusNCBI:XP_422109 · ENTREZ:424262
G. gallusNCBI:XP_418762 · ENTREZ:420663
G. gallusNCBI:XP_416108 · ENTREZ:417866
G. gallusNCBI:XP_001234183 · ENTREZ:424634
G. gallusENTREZ:419227 · UniProtKB:Q5ZLC4 (RCJMB04_6l19 · Q5ZLC4 · IPI00595428)Oxysterol-binding protein⌘
H. sapiensENSEMBL:ENSG00000144645 · UniProtKB:Q9BXB5 (OSBPL10 · OSBP9 · OSB10_HUMAN · ORP10 · Q9BXB5 · IPI00032971)Oxysterol-binding protein-related protein 10⌘
H. sapiensENSEMBL:ENSG00000144909 · UniProtKB:Q9BXB4 (OSBP12 · OSB11_HUMAN · Q9BXB4 · ORP11 · OSBPL11 · IPI00032970)Oxysterol-binding protein-related protein 11⌘
H. sapiensENSEMBL:ENSG00000130703 · UniProtKB:Q9H1P3 (IPI00014137 · KIAA0772 · Q9H1P3 · OSBL2_HUMAN · IPI00220460 · OSBPL2 · ORP2)Oxysterol-binding protein-related protein 2⌘
H. sapiensENSEMBL:ENSG00000070882 · UniProtKB:Q9H4L5 (IPI00162669 · ORP3 · OSBL3_HUMAN · OSBPL3 · IPI00169299 · OSBP3 · Q9H4L5 · IPI00169296 · KIAA0704 · IPI00162670 · IPI00375694 · IPI00375695 · IPI00167053 · IPI00023555)Oxysterol-binding protein-related protein 3⌘
H. sapiensENSEMBL:ENSG00000021762 · UniProtKB:Q9H0X9 (IPI00220116 · OSBPL5 · OBPH1 · KIAA1534 · ORP5 · Q9H0X9 · OSBL5_HUMAN)Oxysterol-binding protein-related protein 5⌘
H. sapiensENSEMBL:ENSG00000079156 · UniProtKB:Q9BZF3 (ORP6 · IPI00385134 · IPI00220568 · OSBL6_HUMAN · OSBPL6 · Q9BZF3)Oxysterol-binding protein-related protein 6⌘
H. sapiensENSEMBL:ENSG00000006025 · UniProtKB:Q9BZF2 (OSBL7_HUMAN · OSBPL7 · Q9BZF2 · ORP7 · IPI00001575)Oxysterol-binding protein-related protein 7⌘
H. sapiensENSEMBL:ENSG00000091039 · UniProtKB:Q9BZF1 (OSBP10 · IPI00394737 · ORP8 · KIAA1451 · IPI00163644 · OSBPL8 · Q9BZF1 · OSBL8_HUMAN)Oxysterol-binding protein-related protein 8⌘
H. sapiensENSEMBL:ENSG00000117859 · UniProtKB:Q96SU4 (Q96SU4 · OSBP4 · OSBL9_HUMAN · OSBPL9 · IPI00077853 · IPI00218449 · ORP9)Oxysterol-binding protein-related protein 9⌘
H. sapiensENSEMBL:ENSG00000110048 · UniProtKB:P22059 (OSBP · IPI00024971 · P22059 · OSBP1 · OSBP1_HUMAN · IPI00440762)Oxysterol-binding protein 1⌘
H. sapiensENSEMBL:ENSG00000184792 · UniProtKB:Q969R2 (OSBP2_HUMAN · IPI00746936 · ORP4 · Q969R2 · OSBPL4 · KIAA1664 · OSBP2)Oxysterol-binding protein 2⌘
M. musculusNCBI:NP_598646 · MGI:MGI:1923784 (ORP-9 · Osbpl9)oxysterol binding protein-like 9⌘
M. musculusNCBI:NP_683761 · MGI:MGI:1921736 (Osbpl10 · OPR-10)oxysterol binding protein-like 10⌘
M. musculusNCBI:NP_780698 · MGI:MGI:2443807 (ORP-8 · Osbpl8)oxysterol binding protein-like 8⌘
M. musculusNCBI:NP_001074903 · MGI:MGI:1918490 (Osbpl7)oxysterol binding protein-like 7⌘
M. musculusUniProtKB:Q8CI95 · MGI:MGI:2146553 (ORP-11 · Osbpl11)oxysterol binding protein-like 11⌘
M. musculusUniProtKB:Q8BX94 · MGI:MGI:2442832 (Osbpl2 · ORP-2)oxysterol binding protein-like 2⌘
M. musculusUniProtKB:Q9DBS9 · MGI:MGI:1918970 (ORP3 · OSBP3 · Osbpl3)oxysterol binding protein-like 3⌘
M. musculusUniProtKB:Q9ER64 · MGI:MGI:1930265 (Obph1 · ORP5 · Osbpl5)oxysterol binding protein-like 5⌘
M. musculusUniProtKB:Q8BXR9 · MGI:MGI:2139014 (ORP-6 · Osbpl6)oxysterol binding protein-like 6⌘
M. musculusUniProtKB:Q3B7Z2 · MGI:MGI:97447 (Osbp)oxysterol binding protein⌘
M. musculusUniProtKB:Q5QNQ6 · MGI:MGI:1921559 (ORP-4 · OSBPL1 · Osbp2)oxysterol binding protein 2⌘
R. norvegicusNCBI:XP_001055606 · RGD:1564287 (Osbpl3)oxysterol binding protein-like 3⌘
R. norvegicusNCBI:XP_001066915 · RGD:1310505
R. norvegicusNCBI:XP_221396 · RGD:1307294 (Osbpl11)oxysterol binding protein-like 11⌘
R. norvegicusNCBI:XP_001081327 · RGD:1309141
R. norvegicusNCBI:XP_344996 · RGD:1308069 (Osbp)oxysterol binding protein⌘
R. norvegicusNCBI:XP_001076888 · RGD:1561652 (Osbpl10)oxysterol binding protein-like 10⌘
R. norvegicusNCBI:XP_243478 · RGD:1561474 (RGD1561474)similar to oxysterol-binding protein-like protein 8 isoform a⌘
R. norvegicusNCBI:XP_242057 · RGD:1308887
R. norvegicusUniProtKB:Q3KR91 (Osbpl9_predicted · IPI00566445 · Q3KR91 · Osbpl9) · RGD:1311508 (Osbpl9)oxysterol binding protein-like 9⌘⌘
R. norvegicusUniProtKB:Q5BK47 · RGD:1311312 (Osbpl2)oxysterol binding protein-like 2⌘
S. cerevisiaeUniProtKB:P35843 · SGD:S000005763 (OSH5 · HES1 · YOR237W)Protein implicated in the regulation of ergosterol biosynthesis⌘
S. cerevisiaeUniProtKB:P35844 · SGD:S000006066 (LPI3 · KES1 · BSR3 · OSH4 · YPL145C)Member of the oxysterol binding protein family, which includes seven yeast homologs⌘
S. cerevisiaeUniProtKB:P35845 · SGD:S000000081 (SWH1 · YAR044W · YAR042W · OSH1)Protein similar to mammalian oxysterol-binding protein⌘
S. cerevisiaeUniProtKB:Q12451 · SGD:S000002177 (YDL019C · OSH2)Member of an oxysterol-binding protein family with seven members in S. cerevisiae⌘
S. cerevisiaeUniProtKB:P38713 · SGD:S000001115 (YHR073W · OSH3)Member of an oxysterol-binding protein family with seven members in S. cerevisiae⌘
S. cerevisiaeUniProtKB:Q02201 · SGD:S000001711 (OSH6 · YKR003W)Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability⌘
S. cerevisiaeUniProtKB:P38755 · SGD:S000001043 (OSH7 · YHR001W)Member of an oxysterol-binding protein family with seven members in S. cerevisiae⌘
S. pombeUniProtKB:O74178 · GeneDB_Spombe:SPBC1271.12 (kes1 · SPBC1271.12)oxysterol binding protein⌘
S. pombeUniProtKB:O94512 · GeneDB_Spombe:SPBC646.08c (SPBC646.08c)oxysterol binding protein⌘
S. pombeUniProtKB:O14340 · GeneDB_Spombe:SPBC2F12.05c (SPBC2F12.05c)sterol binding ankyrin repeat protein⌘
S. pombeUniProtKB:O13944 · GeneDB_Spombe:SPAC23H4.01c (SPAP27G11.01 · SPAC23H4.01c)sterol binding ankyrin repeat protein⌘
S. pombeUniProtKB:O43021 · GeneDB_Spombe:SPBC354.07c (SPBC354.07c)oxysterol binding protein⌘
S. pombeUniProtKB:Q9UUA1 · GeneDB_Spombe:SPCC23B6.01c (SPCC23B6.01c)oxysterol binding protein⌘
ProteinPublicationCurator Notes
UniProtKB:P35844 · SGD:S000006066PMID:15617515 Fairn GD, et al. Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related protein 1 short) in the regulation of vesicular transport. Biochem J. 2005 May 1;387(Pt 3):889-96.The H. sapiens protein Q9BXW6 was expressed in S. cerevisiae, but complementation was not directly tested. The authors assessed the role of human ORP1S (Q9BXW6) deletion mutants for their ability to prevent cell growth of a sec14ts kes1 yeast strain. Human ORP1S can phenocopy yeast Kes1p and inhibit the Sec14p-mediated regulation of vesicular transport from the Golgi.
DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu