P-POD: Princeton Protein Orthology Database: GO3/Jaccard141

This family has 110 members: 6 Caenorhabditis elegans, 24 Danio rerio, 6 Drosophila melanogaster, 16 Gallus gallus, 19 Homo sapiens, 20 Mus musculus, 19 Rattus norvegicus.

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

GO3/Jaccard141
110 members.
OrganismProtein (Synonyms)DescriptionAmiGO
C. elegansUniProtKB:Q18823 · WB:WBGene00016913 (lam-2 · C54D1.5)⌘
C. elegansWB:WBGene00006746 (F41C6.1 · unc-6) · UniProtKB:P34710⌘
C. elegansWB:WBGene00002247 (W03F8.5 · lam-1) · UniProtKB:O44565⌘
C. elegansWB:WBGene00002248 (lam-3 · T22A3.8) · UniProtKB:O45614⌘
C. elegansWB:WBGene00001328 (K08C7.3 · epi-1) · UniProtKB:P91904⌘
C. elegansWB:WBGene00020998 (W03F8.10) · UniProtKB:Q7YZM5 (W03F8.10)Putative uncharacterized protein⌘⌘
D. rerioENSEMBL:ENSDARP00000072598
D. rerioENSEMBL:ENSDARP00000076909
D. rerioENSEMBL:ENSDARP00000096727
D. rerioENSEMBL:ENSDARP00000066604
D. rerioENSEMBL:ENSDARP00000081650
D. rerioENSEMBL:ENSDARP00000053636
D. rerioENSEMBL:ENSDARP00000005383
D. rerioENSEMBL:ENSDARP00000084330
D. rerioENSEMBL:ENSDARP00000058280
D. rerioENSEMBL:ENSDARP00000022733
D. rerioENSEMBL:ENSDARP00000052908
D. rerioUniProtKB:Q8JHV6 · ZFIN:ZDB-GENE-021226-2 (lamb4)laminin, beta 4⌘
D. rerioENSEMBL:ENSDARG00000060396 · UniProtKB:A2BFW5
D. rerioUniProtKB:O42140 · ZFIN:ZDB-GENE-990415-169 (ntn1a)netrin 1a⌘
D. rerioUniProtKB:O42203 · ZFIN:ZDB-GENE-990415-168 (ntn1b)netrin 1b⌘
D. rerioZFIN:ZDB-GENE-050208-475 (si:dkey-121a11.10) · UniProtKB:Q1LXE7⌘
D. rerioUniProtKB:Q2Q1W5 · ZFIN:ZDB-GENE-030131-9823 (lama5)laminin, alpha 5⌘
D. rerioUniProtKB:Q2TJF5 · ZFIN:ZDB-GENE-040724-213 (lama4)laminin, alpha 4⌘
D. rerioUniProtKB:Q45H72 · ZFIN:ZDB-GENE-060118-1 (lama1)laminin, alpha 1⌘
D. rerioENSEMBL:ENSDARG00000033950 · UniProtKB:Q58EP9
D. rerioENSEMBL:ENSDARG00000026491 · UniProtKB:Q5BJ05
D. rerioUniProtKB:B3DJR9 · ZFIN:ZDB-GENE-050310-1 (ntn4)netrin 4⌘
D. rerioZFIN:ZDB-GENE-041210-197 (si:dkey-183c16.5) · UniProtKB:Q5RH37⌘
D. rerioUniProtKB:Q8JHV8 · ZFIN:ZDB-GENE-021226-3 (lamc1)laminin, gamma 1⌘
D. melanogasterUniProtKB:Q00174 · FB:FBgn0002526 (lanA · LanA · laminin · alpha3/5 · Lam · CG10236 · LM-A/alpha1 · Lan · Laminin · hdln · CT28769 · LamA · lamA · headline · LamininA · Lam-A)Laminin A · laminin alpha-chain · alpha3,5 laminin · laminin A · laminin alpha · Laminin alpha3,5 · laminin alpha3,5 · laminin alpha3/5⌘
D. melanogasterUniProtKB:P11046 · FB:FBgn0002527 (lamB1 · beta1 · CG7123 · CT22015 · LanB1 · laminin · Laminin · BcDNA:LD21794 · LM-B1/beta · Lam-B1)Lan B1 · laminin beta1 · laminin B1 · laminin beta · Laminin B1 · laminin beta-chain⌘
D. melanogasterUniProtKB:P15215 · FB:FBgn0002528 (gamma1 · LM-B2/gamma · laminin · DROLAMB2A · LAMB2A · CT11145 · CG3322 · anon-fast-evolving-2H3 · LanB2 · anon-EST:fe2H3 · Laminin · Lam-B2 · lamB2)laminin gamma1 · Laminin B2 · laminin gamma2 · laminin gamma-chain · laminin gamma · laminin B2⌘
D. melanogasterUniProtKB:Q24567 · FB:FBgn0015773 (netrin · Netrin · CG18657 · netA · Netrin-A · CT27014 · NETRIN · NetrinA · netrinA · NetA · D-netrin-A)netrin A · Netrin A⌘
D. melanogasterUniProtKB:Q24568 · FB:FBgn0015774 (NETRIN · netrin · D-netrin-B · CT29512 · NetB · Netrin · Netrin-B · netB · netrinB · CG10521)Netrin B · netrin B⌘
D. melanogasterUniProtKB:Q8IP51 · FB:FBgn0004002 (l(2)09437 · BG:DS03792.1 · A1 · wb · l34Fb · CK02229 · laminin · CG15288 · l(2)br1 · DLAM · CT35236 · l(2)34Fb · LM-A/alpha2 · BEST:CK02229 · lamininW)alpha laminin · wing blistered · lethal 1 in the black-reduced region · Laminin alpha1,2 · D-laminin alpha2 · laminin alpha1,2 · wing blister · lethal group A1⌘
G. gallusNCBI:XP_419746 · ENTREZ:421709
G. gallusNCBI:XP_415454 · ENTREZ:417171
G. gallusNCBI:XP_001231473 · ENTREZ:424336
G. gallusNCBI:XP_419780 · ENTREZ:421749
G. gallusNCBI:XP_001232878 · ENTREZ:396076
G. gallusNCBI:XP_415047 · ENTREZ:396387
G. gallusNCBI:XP_419139 · ENTREZ:374016
G. gallusNCBI:XP_422285 · ENTREZ:408043
G. gallusNCBI:XP_425827 · ENTREZ:428268
G. gallusNCBI:XP_419417 · ENTREZ:421358
G. gallusNCBI:XP_416155 · ENTREZ:417914
G. gallusNCBI:XP_415462 · ENTREZ:417180
G. gallusNCBI:XP_426078 · ENTREZ:428524
G. gallusNCBI:XP_415943 · ENTREZ:396478
G. gallusUniProtKB:Q90922 (NTN1 · NET1_CHICK · Q90922 · IPI00570611 · Netrin-1) · ENTREZ:396389⌘
G. gallusUniProtKB:O57484 (IPI00576346 · O57484) · ENTREZ:373980⌘
H. sapiensENSEMBL:ENSG00000101680 · UniProtKB:P25391 (IPI00375294 · P25391 · LAMA · LAMA1 · LAMA1_HUMAN)Laminin subunit alpha-1⌘
H. sapiensENSEMBL:ENSG00000196569 · UniProtKB:P24043 (LAMA2_HUMAN · LAMA2 · P24043 · LAMM · IPI00844276)Laminin subunit alpha-2⌘
H. sapiensENSEMBL:ENSG00000053747 · UniProtKB:Q16787 (IPI00790353 · LAMA3 · IPI00790908 · LAMA3_HUMAN · LAMNA · Q16787)Laminin subunit alpha-3⌘
H. sapiensENSEMBL:ENSG00000112769 · UniProtKB:Q16363 (IPI00735310 · IPI00329482 · Q16363 · LAMA4_HUMAN · LAMA4)Laminin subunit alpha-4⌘
H. sapiensENSEMBL:ENSG00000130702 · UniProtKB:O15230 (KIAA0533 · LAMA5 · KIAA1907 · LAMA5_HUMAN · O15230 · IPI00783665)Laminin subunit alpha-5⌘
H. sapiensENSEMBL:ENSG00000091136 · UniProtKB:P07942 (IPI00013976 · LAMB1_HUMAN · P07942 · LAMB1)Laminin subunit beta-1⌘
H. sapiensENSEMBL:ENSG00000172037 · UniProtKB:P55268 (LAMB2_HUMAN · LAMS · P55268 · IPI00296922 · LAMB2)Laminin subunit beta-2⌘
H. sapiensENSEMBL:ENSG00000196878 · UniProtKB:Q13751 (LAMB3_HUMAN · LAMNB1 · IPI00299404 · Q13751 · LAMB3)Laminin subunit beta-3⌘
H. sapiensENSEMBL:ENSG00000091128 · UniProtKB:A4D0S4 (IPI00295437 · A4D0S4 · IPI00852842 · IPI00783447 · LAMB4_HUMAN · IPI00877012 · LAMB4)Laminin subunit beta-4⌘
H. sapiensENSEMBL:ENSG00000135862 · UniProtKB:P11047 (LAMC1 · P11047 · IPI00298281 · LAMC1_HUMAN · LAMB2)Laminin subunit gamma-1⌘
H. sapiensENSEMBL:ENSG00000058085 · UniProtKB:Q13753 (IPI00015117 · LAMC2_HUMAN · IPI00220572 · LAMC2 · LAMB2T · LAMNB2 · Q13753)Laminin subunit gamma-2⌘
H. sapiensENSEMBL:ENSG00000050555 · UniProtKB:Q9Y6N6 (LAMC3_HUMAN · Q9Y6N6 · IPI00641172 · LAMC3)Laminin subunit gamma-3⌘
H. sapiensENSEMBL:ENSG00000142233 · UniProtKB:Q8WTR8 (Netrin-5 · IPI00645833 · Q8WTR8 · NET5_HUMAN · IPI00102812 · NTN5)⌘
H. sapiensENSEMBL:ENSG00000065320 · UniProtKB:O95631 (NET1_HUMAN · NTN1 · IPI00006732 · NTN1L · O95631 · Netrin-1)⌘
H. sapiensENSEMBL:ENSG00000162068 · UniProtKB:O00634 (NET3_HUMAN · IPI00006193 · O00634 · NTN3 · Netrin-3 · NTN2L)⌘
H. sapiensENSEMBL:ENSG00000074527 · UniProtKB:Q9HB63 (Q9HB63 · NET4_HUMAN · IPI00472613 · NTN4 · IPI00385236 · IPI00328091 · Netrin-4)⌘
H. sapiensENSEMBL:ENSG00000162631 · UniProtKB:Q9Y2I2 (IPI00478746 · IPI00412988 · IPI00412989 · LMNT1 · NTNG1_HUMAN · KIAA0976 · UNQ571/PRO1133 · IPI00478407 · IPI00477903 · NTNG1 · IPI00479203 · Netrin-G1 · Q9Y2I2)⌘
H. sapiensENSEMBL:ENSG00000196358 · UniProtKB:Q96CW9 (Q96CW9 · IPI00843936 · KIAA1857 · UNQ9381/PRO34206 · LMNT2 · IPI00432766 · NTNG2_HUMAN · Netrin-G2 · NTNG2)⌘
H. sapiensENSEMBL:ENSG00000042781 · UniProtKB:O75445 (IPI00741527 · IPI00289540 · O75445 · USH2A_HUMAN · USH2A · IPI00410150 · Usherin)⌘
M. musculusUniProtKB:P19137 · MGI:MGI:99892 (Lama · Lama1)laminin, alpha 1⌘
M. musculusUniProtKB:Q60675 · MGI:MGI:99912 (merosin · mer · Lama2)laminin, alpha 2⌘
M. musculusUniProtKB:Q61789 · MGI:MGI:99909 (Lama3 · [a]3B)nicein, 150kDa · laminin, alpha 3⌘
M. musculusUniProtKB:P97927 · MGI:MGI:109321 (Lama4)laminin, alpha 4 · laminin [a]4⌘
M. musculusUniProtKB:Q61001 · MGI:MGI:105382 (Lama5)laminin, alpha 5⌘
M. musculusUniProtKB:P02469 · MGI:MGI:96743 (C81607 · C80098 · Lamb-1 · Lamb1-1)laminin B1 subunit 1⌘
M. musculusUniProtKB:Q61292 · MGI:MGI:99916 (Lamb2 · Lams · Lamb-2)Laminin S · laminin, beta 2⌘
M. musculusUniProtKB:Q61087 · MGI:MGI:99915 (Lamb3)nicein, 125kDa · laminin, beta 3⌘
M. musculusUniProtKB:P02468 · MGI:MGI:99914 (Lamc1 · Lamb2)laminin, gamma 1⌘
M. musculusUniProtKB:Q61092 · MGI:MGI:99913 (Lamc2)nicein, 100kDa · laminin, gamma 2⌘
M. musculusUniProtKB:Q9R0B6 · MGI:MGI:1344394 (Lamc3)laminin gamma 3⌘
M. musculusUniProtKB:Q3UQ22 · MGI:MGI:2685330 (Ntn5 · LOC243967)netrin 5⌘
M. musculusUniProtKB:O09118 · MGI:MGI:105088 (Ntn1 · Netrin-1)netrin 1⌘
M. musculusUniProtKB:Q9R1A3 · MGI:MGI:1341188 (Ntn3 · Ntn2l)netrin 3⌘
M. musculusUniProtKB:Q9JI33 · MGI:MGI:1888978 (Ntn4 · beta-netrin)netrin 4⌘
M. musculusUniProtKB:Q8R4G0 · MGI:MGI:1934028 (Ntng1 · Lmnt1)netrin G1⌘
M. musculusUniProtKB:Q8R4F1 · MGI:MGI:2159341 (Lmnt2 · Ntng2)netrin G2⌘
M. musculusUniProtKB:Q2QI47 · MGI:MGI:1341292 (Ush2a · LOC381317 · MUSH2A · Usherin · LOC269160)Usher syndrome 2A (autosomal recessive, mild) homolog (human)⌘
M. musculusMGI:MGI:1923470 · UniProtKB:A2AKX0
M. musculusNCBI:XP_284307 · MGI:MGI:3037723
R. norvegicusNCBI:XP_001080341 · RGD:1565947 (RGD1565947)similar to netrin 4⌘
R. norvegicusNCBI:XP_001071922 · RGD:1563465 (Ntng1)netrin G1⌘
R. norvegicusNCBI:NP_001101300 · RGD:1309399 (Lamc3)laminin gamma 3⌘
R. norvegicusNCBI:XP_001062273 · RGD:1308889 (Lama2)laminin, alpha 2⌘
R. norvegicusNCBI:XP_341134 · RGD:1308656
R. norvegicusNCBI:XP_001075963 · RGD:1306311 (Lamb1)laminin, beta 1⌘
R. norvegicusNCBI:XP_001065756 · RGD:1560269 (RGD1560269)similar to usherin isoform B⌘
R. norvegicusNCBI:XP_001061082 · RGD:1595304
R. norvegicusNCBI:XP_218653 · RGD:1565197
R. norvegicusNCBI:XP_001076071 · RGD:1307089 (Ntng2)netrin G2⌘
R. norvegicusNCBI:XP_001061207 · RGD:1560062 (Lama4)laminin, alpha 4⌘
R. norvegicusUniProtKB:P15800 · RGD:2988 (Lamb2)laminin, beta 2⌘
R. norvegicusUniProtKB:Q924Z9 · RGD:619809 (Ntn1)netrin 1⌘
R. norvegicusUniProtKB:Q8K3K1 · RGD:628777 (Ush2a)Usher syndrome 2A homolog (human)⌘
R. norvegicusUniProtKB:P70570 (Lama3 · IPI00189741 · P70570) · RGD:628776 (Lama3)laminin, alpha 3⌘⌘
R. norvegicusUniProtKB:P70636 · RGD:621023 (Lama5)laminin, alpha 5⌘
R. norvegicusUniProtKB:P70637 · RGD:1562668 (Lamb3)laminin, beta 3⌘
R. norvegicusUniProtKB:Q924Z8 · RGD:619811 (Ntn2l)netrin 2-like (chicken)⌘
R. norvegicusNCBI:NP_001101707 · RGD:1307207 (Lama1)laminin, alpha 1⌘

No functional conservation results.

DescriptionSuffix
Sequences in this family.fasta
mafft aligned Fasta file.afasta
phyml newick file.newick
Notung rooted & rearranged newick file.newick.rooting.0.rearrange.0
Notung Homolog Table.newick.rooting.0.rearrange.0.homologs.csv
OMIM (11)
ENSEMBL:ENSG00000053747 · UniProtKB:Q16787#607855 MUSCULAR DYSTROPHY, CONGENITAL MEROSIN-DEFICIENT, 1A; MDC1A;;MUSCULAR DYSTROPHY, CONGENITAL MEROSIN-DEFICIENTMUSCULAR DYSTROPHY, CONGENITAL, DUE TO PARTIAL LAMA2 DEFICIENCY, INCLUDED
ENSEMBL:ENSG00000091136 · UniProtKB:P07942#245660 LARYNGOONYCHOCUTANEOUS SYNDROME; LOCS;;LOGIC SYNDROME
#226700 EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, HERLITZ TYPE;;JEB-HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ-PEARSON TYPE;;HERLITZ-PEARSON-TYPE EPIDERMOLYSIS BULLOSA;;EPIDERMOLYSIS BULLOSA LETALIS
ENSEMBL:ENSG00000172037 · UniProtKB:P55268+150240 LAMININ, BETA-1; LAMB1NEONATAL CUTIS LAXA WITH MARFANOID PHENOTYPE, INCLUDED;;CUTIS LAXA-MARFANOID SYNDROME, INCLUDED
ENSEMBL:ENSG00000196878 · UniProtKB:Q13751#609049 PIERSON SYNDROME;;MICROCORIA-CONGENITAL NEPHROTIC SYNDROMENEPHROTIC SYNDROME, CONGENITAL, WITH OR WITHOUT OCULAR ABNORMALITIES,INCLUDED;;NEPHROTIC SYNDROME, CONGENITAL, WITH OCULAR ABNORMALITIES AND CONGENITALMYASTHENIC SYNDROME, INCLUDED
ENSEMBL:ENSG00000058085 · UniProtKB:Q13753#226700 EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, HERLITZ TYPE;;JEB-HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ-PEARSON TYPE;;HERLITZ-PEARSON-TYPE EPIDERMOLYSIS BULLOSA;;EPIDERMOLYSIS BULLOSA LETALIS
#226650 EPIDERMOLYSIS BULLOSA, JUNCTIONAL, NON-HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, NON-HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, PROGRESSIVE;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, SEVERE NONLETHAL;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, DISENTIS TYPE;;EPIDERMOLYSIS BULLOSA, GENERALIZED ATROPHIC BENIGN; GABEBEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT, INCLUDED;;JUNCTIONAL EPIDERMOLYSIS BULLOSA INVERSA, INCLUDED;;JEB-I, INCLUDED
ENSEMBL:ENSG00000042781 · UniProtKB:O75445#226700 EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA JUNCTIONALIS, HERLITZ TYPE;;JEB-HERLITZ TYPE;;EPIDERMOLYSIS BULLOSA, JUNCTIONAL, HERLITZ-PEARSON TYPE;;HERLITZ-PEARSON-TYPE EPIDERMOLYSIS BULLOSA;;EPIDERMOLYSIS BULLOSA LETALIS
ENSEMBL:ENSG00000042781 · UniProtKB:O75445+608400 USH2A GENE; USH2A;;USHERIN;;USH2; US2RETINITIS PIGMENTOSA 39, INCLUDED; RP39, INCLUDED
#276901 USHER SYNDROME, TYPE IIA; USH2A
#268000 RETINITIS PIGMENTOSA; RP
Send questions, suggestions, and comments to: yfgdb@genomics.princeton.edu