This family has 21 members: 9 Arabidopsis thaliana, 1 Caenorhabditis elegans, 1 Danio rerio, 2 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
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| Organism | Protein (Synonyms) | Description | AmiGO |
|---|---|---|---|
| A. thaliana | NCBI:NP_177013.1 · TAIR:locus:2201292 (T26J14_3 · AT1G68460 · ATIPT1 · T26J14.3) | ATP/ADP ISOPENTENYLTRANSFERASE · isopentenyltransferase 1 |  |
| A. thaliana | NCBI:NP_197405.1 · TAIR:locus:2179629 (T16G12.80 · T16G12_80 · IPT5 · AT5G19040 · ATIPT5) | | |
| A. thaliana | NCBI:NP_851043.1 · TAIR:locus:2147735 (F28I16_190 · F28I16.190 · AT5G20040 · ATIPT9) | | |
| A. thaliana | NCBI:NP_566735.1 · TAIR:locus:2088025 (MDB19.12 · ATIPT7 · AT3G23630) | | |
| A. thaliana | NCBI:NP_565658.1 · TAIR:locus:2042103 (IPPT · ATIPT2 · AT2G27760) | TRNA ISOPENTENYLTRANSFERASE 2 | |
| A. thaliana | NCBI:NP_173912.1 · TAIR:locus:2031205 (F2J7.12 · ATIPT6 · F2J7_12 · AT1G25410) | | |
| A. thaliana | NCBI:NP_194196.1 · TAIR:locus:2121979 (F22K18_150 · F22K18.150 · ATIPT4 · AT4G24650) | | |
| A. thaliana | NCBI:NP_567138.1 · TAIR:locus:2099177 (T20O10.210 · AT3G63110 · IPT3 · ATIPT3) | ISOPENTENYLTRANSFERASE 3 · ARABIDOPSIS THALIANA ISOPENTENYLTRANSFERASE 3 | |
| A. thaliana | NCBI:NP_188547.1 · TAIR:locus:2094128 (ATIPT8 · MVI11.16 · PGA22 · AT3G19160) | ATP/ADP ISOPENTENYLTRANSFERASES | |
| C. elegans | WB:WBGene00001740 (ZC395.6 · gro-1) · UniProtKB:Q9GYG3 | | |
| D. rerio | ZFIN:ZDB-GENE-060503-297 (si:ch211-194e15.1) · UniProtKB:Q1LWL7 | | |
| D. discoideum | NCBI:EAL71157.1 · dictyBase:DDB_G0273039 (iptC · iptC-1) | putative isopentenyltransferase, putative isopentenylpyrophosphate (IPP) transferase | |
| D. discoideum | UniProtKB:Q54EG2 · dictyBase:DDB_G0291528 (iptB) | putative isopentenyltransferase, putative isopentenylpyrophosphate (IPP) transferase | |
| D. melanogaster | FB:FBgn0043799 (BEST:LD10347 · CG31381) · UniProtKB:Q8IMV0 | | |
| E. coli | UniProtKB:P16384 · ECOLI:EG10595-MONOMER (miaA · trpX · MiaA · b4171 · ECK4167) | delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase | |
| G. gallus | NCBI:XP_417825 · ENTREZ:419678 | ||
| H. sapiens | ENSEMBL:ENSG00000043514 · UniProtKB:Q9H3H1 (IPI00513725 · IPI00419306 · MOD5_HUMAN · IPI00164286 · TRIT1 · Q9H3H1 · IPI00419305 · IPT · IPI00783082 · MOD5) | tRNA isopentenyltransferase, mitochondrial | |
| M. musculus | UniProtKB:Q80UN9 · MGI:MGI:1914216 (Trit1 · MOD5) | tRNA isopentenyltransferase 1 | |
| R. norvegicus | NCBI:XP_001054252 · RGD:1304781 | ||
| S. cerevisiae | UniProtKB:P07884 · SGD:S000005800 (YOR274W · MOD5) | Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs | |
| S. pombe | UniProtKB:Q9UT75 · GeneDB_Spombe:SPAC343.15 (tit1 · SPAC343.15 · mod5) | tRNA isopentenyltransferase | |
| Protein | Publication | Curator Notes | |
|---|---|---|---|
| UniProtKB:P07884 · SGD:S000005800 |  11999372 Golovko A, et al. Identification of a tRNA isopentenyltransferase gene from Arabidopsis thaliana. Plant Mol Biol. 2002 May;49(2):161-9. | The A. thaliana protein AT2G27760.1 complements a homologous mutation in S. cerevisiae. | |
| UniProtKB:P07884 · SGD:S000005800 | 17450376 Yevdakova NA, et al. Characterisation of a prokaryote-type tRNA-isopentenyltransferase gene from the moss Physcomitrella patens. Planta. 2007 Aug;226(3):683-95. | The P. patens protein PpIPT1 complements a homologous mutation in S. cerevisiae. This paper shows that P. patens PpIPT1 complements a yeast mod5-1 mutant. | |
| UniProtKB:P07884 · SGD:S000005800 | 11111046 Golovko A, et al. Cloning of a human tRNA isopentenyl transferase. Gene. 2000 Nov 27;258(1-2):85-93. | The H. sapiens protein Q9H3H1 complements a homologous mutation in S. cerevisiae. | |
| UniProtKB:P07884 · SGD:S000005800 | 15870694 Spinola M, et al. Identification and functional characterization of the candidate tumor suppressor gene TRIT1 in human lung cancer. Oncogene. 2005 Aug 18;24(35):5502-9. | The H. sapiens protein Q9H3H1 complements a homologous mutation in S. cerevisiae. |
| Description | Suffix |
|---|---|
| Sequences in this family | .fasta |
| mafft aligned Fasta file | .afasta |
| phyml newick file | .newick |
| Notung rooted & rearranged newick file | .newick.rooting.0.rearrange.0 |
| Notung Homolog Table | .newick.rooting.0.rearrange.0.homologs.csv |