P-POD: Princeton Protein Orthology Database: GO3/Jaccard101

This family has 139 members: 22 Arabidopsis thaliana, 6 Caenorhabditis elegans, 16 Danio rerio, 4 Dictyostelium discoideum, 11 Drosophila melanogaster, 2 Escherichia coli, 13 Gallus gallus, 13 Homo sapiens, 17 Mus musculus, 24 Rattus norvegicus, 6 Saccharomyces cerevisiae, 5 Schizosaccharomyces pombe.

• Protein Family
• Functional Conservation (9)
• Download Files (5)
• Disease References (1)

Interactive Java Applets: Notung Tree Analysis · Jalview Alignment

139 members.

Organism	Protein (Synonyms)	Description	AmiGO
A. thaliana	NCBI:NP_189997.1 · TAIR:locus:2081378 (F26G5.60 · ATJ3 · ATJ · AT3G44110)
A. thaliana	NCBI:NP_565533.1 · TAIR:locus:2041258 (AT2G22360 · F14M13_24 · F14M13.24)
A. thaliana	NCBI:NP_191819.1 · TAIR:locus:2081725 (AT3G62600 · ATERDJ3B · F26K9.30)
A. thaliana	NCBI:NP_565770.1 · TAIR:locus:505006286 (AT2G33735)
A. thaliana	NCBI:NP_190377.1 · TAIR:locus:2097880 (T17F15.190 · AT3G47940)
A. thaliana	NCBI:NP_172506.1 · TAIR:locus:2012743 (F14N23.23 · F14N23_23 · AT1G10350)
A. thaliana	NCBI:NP_565227.1 · TAIR:locus:2016234 (AT1G80030 · F18B13_12 · F18B13.12)
A. thaliana	NCBI:NP_197935.1 · TAIR:locus:2179429 (T14C9_70 · T14C9.70 · AT5G25530)
A. thaliana	NCBI:NP_568076.1 · TAIR:locus:2140035 (T5J17_130 · AT4G39960 · T5J17.130)
A. thaliana	NCBI:NP_195759.1 · TAIR:locus:2179127 (T10O8_100 · T10O8.100 · AT5G01390)
A. thaliana	NCBI:NP_172571.1 · TAIR:locus:2197429 (AT1G11040 · T19D16.7 · T19D16_7)
A. thaliana	TAIR:locus:2825170 (F23H11.4 · AT1G59725 · F23H11_4) · NCBI:NP_176181.1
A. thaliana	NCBI:NP_188410.2 · TAIR:locus:2088585 (AT3G17830 · MEB5.5)
A. thaliana	NCBI:NP_568412.1 · TAIR:locus:505006628 (ATJ2 · AT5G22060)
A. thaliana	NCBI:NP_179646.1 · TAIR:locus:2054809 (T13C7.15 · AT2G20560 · T13C7_15)
A. thaliana	NCBI:NP_179645.1 · TAIR:locus:2054799 (T13C7.14 · T13C7_14 · AT2G20550)
A. thaliana	NCBI:NP_175080.2 · TAIR:locus:2205856 (T7O23.16 · AT1G44160 · T7O23_16)
A. thaliana	NCBI:NP_187503.1 · TAIR:locus:2097638 (AT3G08910 · T16O11.15)
A. thaliana	NCBI:NP_194577.1 · TAIR:locus:2121368 (F20O9.160 · F20O9_160 · AT4G28480)
A. thaliana	NCBI:NP_568690.1 · TAIR:locus:2162692 (GFA2 · MDN11_11 · MDN11.11 · AT5G48030)	GAMETOPHYTIC FACTOR 2
A. thaliana	NCBI:NP_197168.1 · TAIR:locus:2174170 (MTG13.10 · MTG13_10 · AT5G16650)
A. thaliana	NCBI:NP_174142.1 · TAIR:locus:2032175 (F3H9.13 · F3H9_13 · ATJ · ATJ1 · AT1G28210)
C. elegans	WB:WBGene00001028 (F22B7.5 · dnj-10) · UniProtKB:Q8TA83 (F22B7.5 · DNJ10_CAEEL · dnj-10)	DnaJ homolog dnj-10
C. elegans	WB:WBGene00001038 (T15H9.7 · dnj-20) · UniProtKB:Q8MPX3
C. elegans	WB:WBGene00001037 (T05C3.5 · dnj-19) · UniProtKB:O16303
C. elegans	WB:WBGene00001030 (F39B2.10 · dnj-12) · UniProtKB:O45502
C. elegans	WB:WBGene00001031 (F54D5.8 · dnj-13) · UniProtKB:Q20774
C. elegans	WB:WBGene00001042 (W03A5.7 · dnj-24) · UniProtKB:Q9TY07
D. rerio	ENSEMBL:ENSDARP00000067931
D. rerio	ENSEMBL:ENSDARP00000088330
D. rerio	ZFIN:ZDB-GENE-061013-537 (zgc:153268) · UniProtKB:Q08BM3
D. rerio	ZFIN:ZDB-GENE-051127-45 (zgc:122979) · UniProtKB:Q2YDS3
D. rerio	UniProtKB:Q568I8 · ZFIN:ZDB-GENE-040910-4 (dnajb13)	DnaJ (Hsp40) related, subfamily B, member 13
D. rerio	ZFIN:ZDB-GENE-040801-192 (zgc:91922) · UniProtKB:Q6DEF3
D. rerio	UniProtKB:Q6DEJ4 · ZFIN:ZDB-GENE-040801-90 (dnajb1)	DnaJ (Hsp40) homolog, subfamily B, member 1
D. rerio	ZFIN:ZDB-GENE-040718-45 (zgc:92148) · UniProtKB:Q6DHR2
D. rerio	UniProtKB:Q7SXK8 · ZFIN:ZDB-GENE-040115-3 (dnaja3b)	DnaJ (Hsp40) homolog, subfamily A, member 3B
D. rerio	UniProtKB:Q7ZUW0 · ZFIN:ZDB-GENE-030131-7837 (dnaja3a)	DnaJ (Hsp40) homolog, subfamily A, member 3A
D. rerio	UniProtKB:Q7ZVS0 · ZFIN:ZDB-GENE-030131-2884 (dnaja2l)	DnaJ (Hsp40) homolog, subfamily A, member 2, like
D. rerio	ZFIN:ZDB-GENE-030131-5455 (zgc:55492) · UniProtKB:Q7ZVY8
D. rerio	UniProtKB:Q7ZW83 · ZFIN:ZDB-GENE-040426-1122 (dnajb6)	DnaJ (Hsp40) homolog, subfamily B, member 6
D. rerio	UniProtKB:Q803A9 · ZFIN:ZDB-GENE-031113-9 (dnajb11)	DnaJ (Hsp40) homolog, subfamily B, member 11
D. rerio	UniProtKB:Q803K1 · ZFIN:ZDB-GENE-030131-2642 (dnaja1l)	DnaJ (Hsp40) homolog, subfamily A, member 1, like
D. rerio	UniProtKB:Q7ZUP5 · ZFIN:ZDB-GENE-040426-2884 (dnaja2)	DnaJ (Hsp40) homolog, subfamily A, member 2
D. discoideum	UniProtKB:Q54ED3 · dictyBase:DDB_G0291568 (DDB_G0291568)	heat shock protein DnaJ family protein
D. discoideum	UniProtKB:Q54SQ0 · dictyBase:DDB_G0282313 (DDB_G0282313)	heat shock protein DnaJ family protein
D. discoideum	UniProtKB:Q54VQ1 · dictyBase:DDB_G0280037 (ddj1)	heat shock protein
D. discoideum	UniProtKB:Q54XR6 · dictyBase:DDB_G0278789 (DDB_G0278789)	heat shock protein DnaJ family protein
D. melanogaster	UniProtKB:Q24133 · FB:FBgn0015657 (anon-WO0140519.166 · CG10578 · DroJ1 · DnaJ-like-1 · anon-WO0172774.135 · dHDJ1 · dHdj1 · DROJ1 · droj1 · HSP40/HDJ1 · DnaJ-1 · HSP40 · dHDJ1/HSP40 · Hsp40 · dhdJ1 · EU3500 · DNAJ1 · dhdj-1 · Hsp-40)	dnaJ like1 · DnaJ1 64EF
D. melanogaster	UniProtKB:Q27237 · FB:FBgn0002174 (l(2)tud · l(2)701 · TID56 · l(2)tid · tid · DnaJ · CG5504 · l(2)td)	l(2)tumorous imaginal discs · cDNA 10D · lethal (2) tumorous imaginal discs · l(2)tumorous disc
D. melanogaster	FB:FBgn0034091 (dmrj · dMRJ · mrj · CG8448) · UniProtKB:Q7JUZ6
D. melanogaster	FB:FBgn0035852 (anon-WO0140519.72 · CG7387) · UniProtKB:Q8SZX1
D. melanogaster	UniProtKB:Q8T922 · FB:FBgn0032474 (CG9828 · dDnaJ-H · DnaJ-H · NEST:bs08d07 · dHdj2)	DnaJ homolog
D. melanogaster	FB:FBgn0038145 (DnaJ-like-2 · CG8863 · Droj2 · anon-WO0118547.404) · UniProtKB:Q9VFV9
D. melanogaster	FB:FBgn0037151 (CG7130) · UniProtKB:Q9VNW0
D. melanogaster	FB:FBgn0031256 (CG4164) · UniProtKB:Q9VPQ2
D. melanogaster	FB:FBgn0031322 (CG5001) · UniProtKB:Q9VPY9
D. melanogaster	FB:FBgn0035273 (CG12020) · UniProtKB:Q9W083
D. melanogaster	FB:FBgn0030207 (CG2887) · UniProtKB:Q9W2U5
E. coli	UniProtKB:P36659 · ECOLI:EG12193-MONOMER (ECK0991 · cbpA · CbpA · b1000)	CbpA monomer
E. coli	UniProtKB:P08622 · ECOLI:EG10240-MONOMER (GroP · b0015 · B0015 · grpC · DnaJ · ECK0015 · groP · GrpC · dnaJ)	co-chaperone with DnaK · chaperone with DnaK; heat shock protein · chaperone with DnaK heat shock protein · chaperone Hsp40
G. gallus	NCBI:XP_424983 · ENTREZ:427409
G. gallus	NCBI:XP_414967 · ENTREZ:416671
G. gallus	NCBI:XP_422682 · ENTREZ:424868
G. gallus	NCBI:XP_001233013 · ENTREZ:770080
G. gallus	NCBI:XP_001235058 · ENTREZ:771831
G. gallus	NCBI:XP_428272 · ENTREZ:430721
G. gallus	NCBI:XP_001233254 · ENTREZ:424550
G. gallus	NCBI:XP_417251 · ENTREZ:419060
G. gallus	NCBI:XP_413746 · ENTREZ:415360
G. gallus	NCBI:XP_424624 · ENTREZ:427022
G. gallus	ENTREZ:420448 · UniProtKB:Q5F3Z5 (RCJMB04_4b8 · IPI00584191 · Q5F3Z5 · DNJB6_CHICK · DNAJB6)	DnaJ homolog subfamily B member 6
G. gallus	UniProtKB:Q5ZIZ7 (Q5ZIZ7 · RCJMB04_22f12 · IPI00573759) · ENTREZ:415744
G. gallus	UniProtKB:Q5ZJV3 (RCJMB04_15h2 · IPI00598722 · Q5ZJV3) · ENTREZ:427376
H. sapiens	ENSEMBL:ENSG00000090520 · UniProtKB:Q9UBS4 (EDJ · ERJ3 · IPI00008454 · Q9UBS4 · PSEC0121 · DNAJB11 · DJB11_HUMAN · UNQ537/PRO1080)	DnaJ homolog subfamily B member 11
H. sapiens	ENSEMBL:ENSG00000187726 · UniProtKB:P59910 (TSARG6 · P59910 · IPI00374263 · DNAJB13 · DJB13_HUMAN · IPI00374262 · TSARG3)	DnaJ homolog subfamily B member 13
H. sapiens	ENSEMBL:ENSG00000086061 · UniProtKB:P31689 (HSJ2 · DNAJA1 · HSPF4 · P31689 · IPI00012535 · HDJ2 · DNAJ2 · DNJA1_HUMAN)	DnaJ homolog subfamily A member 1
H. sapiens	ENSEMBL:ENSG00000069345 · UniProtKB:O60884 (DNAJA2 · IPI00032406 · CPR3 · HIRIP4 · O60884 · DNJA2_HUMAN)	DnaJ homolog subfamily A member 2
H. sapiens	ENSEMBL:ENSG00000103423 · UniProtKB:Q96EY1 (TID1 · HCA57 · DNJA3_HUMAN · IPI00294610 · DNAJA3 · IPI00179187 · Q96EY1)	DnaJ homolog subfamily A member 3, mitochondrial
H. sapiens	ENSEMBL:ENSG00000140403 · UniProtKB:Q8WW22 (DNJA4_HUMAN · IPI00853174 · Q8WW22 · DNAJA4)	DnaJ homolog subfamily A member 4
H. sapiens	ENSEMBL:ENSG00000132002 · UniProtKB:P25685 (DNAJ1 · DNAJB1 · HDJ1 · DNJB1_HUMAN · P25685 · HSPF1 · IPI00015947)	DnaJ homolog subfamily B member 1
H. sapiens	ENSEMBL:ENSG00000135924 · UniProtKB:P25686 (HSPF3 · DNJB2_HUMAN · IPI00220102 · IPI00874105 · DNAJB2 · P25686 · HSJ1)	DnaJ homolog subfamily B member 2
H. sapiens	ENSEMBL:ENSG00000162616 · UniProtKB:Q9UDY4 (IPI00003848 · HLJ1 · DNAJB4 · DNAJW · Q9UDY4 · DNJB4_HUMAN)	DnaJ homolog subfamily B member 4
H. sapiens	ENSEMBL:ENSG00000137094 · UniProtKB:O75953 (DNJB5_HUMAN · HSC40 · IPI00871830 · O75953 · DNAJB5 · IPI00016855)	DnaJ homolog subfamily B member 5
H. sapiens	ENSEMBL:ENSG00000105993 · UniProtKB:O75190 (HSJ2 · IPI00098523 · MRJ · DNJB6_HUMAN · IPI00024523 · MSJ1 · O75190 · DNAJB6 · IPI00556073)	DnaJ homolog subfamily B member 6
H. sapiens	ENSEMBL:ENSG00000172404 · UniProtKB:Q7Z6W7 (DNJB7_HUMAN · DNAJB7 · HSC3 · Q7Z6W7 · IPI00103726)	DnaJ homolog subfamily B member 7
H. sapiens	ENSEMBL:ENSG00000179407 · UniProtKB:Q8NHS0 (Q8NHS0 · IPI00169308 · DNJB8_HUMAN · DNAJB8)	DnaJ homolog subfamily B member 8
M. musculus	NCBI:XP_984887 · MGI:MGI:3646286
M. musculus	NCBI:NP_083420 · MGI:MGI:1922264 (4930503B20Rik)	RIKEN cDNA 4930503B20 gene
M. musculus	NCBI:XP_123650 · MGI:MGI:3643039
M. musculus	UniProtKB:Q9QYI5 · MGI:MGI:1928739 (mDj8 · Dnajb10 · Dnajb2)	DnaJ (Hsp40) homolog, subfamily B, member 2
M. musculus	UniProtKB:Q99KV1 · MGI:MGI:1915088 (Dj9 · Dnajb11 · ABBP-2)	DnaJ (Hsp40) homolog, subfamily B, member 11
M. musculus	UniProtKB:Q80Y75 · MGI:MGI:1916637 (Dnajb13)	DnaJ (Hsp40) related, subfamily B, member 13
M. musculus	UniProtKB:P63037 · MGI:MGI:1270129 (Hsj2 · Dnaja1 · Nedd7)	DnaJ (Hsp40) homolog, subfamily A, member 1
M. musculus	UniProtKB:Q9QYJ0 · MGI:MGI:1931882 (Dnaja2 · PRO3015 · mDj3 · HIRIP4 · DNJ3)	DnaJ (Hsp40) homolog, subfamily A, member 2
M. musculus	UniProtKB:Q99M87 · MGI:MGI:1933786 (Tid-1 · Dnaja3)	DnaJ (Hsp40) homolog, subfamily A, member 3
M. musculus	UniProtKB:Q9JMC3 · MGI:MGI:1927638 (Hsj4 · Dj4 · Dnaja4)	DnaJ (Hsp40) homolog, subfamily A, member 4
M. musculus	UniProtKB:Q9QYJ3 · MGI:MGI:1931874 (Hsp40 · Dnajb1)	DnaJ (Hsp40) homolog, subfamily B, member 1
M. musculus	UniProtKB:O35723 · MGI:MGI:1306822 (MSJ-1 · Dnajb3 · Msj1 · Hsj3)	DnaJ (Hsp40) homolog, subfamily B, member 3
M. musculus	UniProtKB:Q9D832 · MGI:MGI:1914285 (Dnajb4)	DnaJ (Hsp40) homolog, subfamily B, member 4
M. musculus	UniProtKB:O89114 · MGI:MGI:1930018 (Hsp40-3 · Dnajb5 · Hsc40)	DnaJ (Hsp40) homolog, subfamily B, member 5
M. musculus	UniProtKB:O54946 · MGI:MGI:1344381 (Mrj · mDj4 · Dnajb6)	DnaJ (Hsp40) homolog, subfamily B, member 6
M. musculus	UniProtKB:Q9QYI8 · MGI:MGI:1914012 (mDj5 · Dnajb7)	DnaJ (Hsp40) homolog, subfamily B, member 7
M. musculus	UniProtKB:Q9QYI7 · MGI:MGI:1922801 (mDj6 · Dnajb8)	DnaJ (Hsp40) homolog, subfamily B, member 8
R. norvegicus	NCBI:XP_001069407 · RGD:1304725 (Dnajb1)	DnaJ (Hsp40) homolog, subfamily B, member 1
R. norvegicus	NCBI:XP_001070740 · RGD:1591035 (LOC689593)	similar to DnaJ (Hsp40) homolog, subfamily B, member 10 isoform 2
R. norvegicus	NCBI:XP_233767 · RGD:1307453 (Dnajb5)	DnaJ (Hsp40) homolog, subfamily B, member 5
R. norvegicus	NCBI:XP_001060452 · RGD:1583553 (LOC681138)	similar to DnaJ (Hsp40) homolog, subfamily B, member 6
R. norvegicus	NCBI:XP_001071457 · RGD:1561981 (Dnajb8)	DnaJ (Hsp40) homolog, subfamily B, member 8
R. norvegicus	NCBI:XP_001076562 · RGD:1593690
R. norvegicus	NCBI:XP_001073579 · RGD:1583989
R. norvegicus	NCBI:XP_344988 · RGD:1562684
R. norvegicus	NCBI:XP_001069503 · RGD:1589047 (Dnajb7)	DnaJ (Hsp40) homolog, subfamily B, member 7
R. norvegicus	NCBI:XP_576590 · RGD:1560574
R. norvegicus	NCBI:XP_001057422 · RGD:1594215
R. norvegicus	NCBI:XP_576026 · RGD:1565241
R. norvegicus	NCBI:XP_001061194 · RGD:1586177 (LOC301379)	similar to DnaJ (Hsp40) homolog, subfamily C, member 14
R. norvegicus	NCBI:XP_001072911 · RGD:1584350
R. norvegicus	UniProtKB:Q6TUG0 · RGD:1307373 (Dnajb11)	DnaJ (Hsp40) homolog, subfamily B, member 11
R. norvegicus	UniProtKB:P63036 · RGD:620942 (Dnaja1)	DnaJ (Hsp40) homolog, subfamily A, member 1
R. norvegicus	RGD:71001 (Dnaja2) · UniProtKB:O35824 (Dnaja2 · IPI00213062 · O35824 · DNJA2_RAT)	DnaJ (Hsp40) homolog, subfamily A, member 2 · DnaJ homolog subfamily A member 2
R. norvegicus	UniProtKB:Q6AYU3 · RGD:1308207 (Dnajb6)	DnaJ (Hsp40) homolog, subfamily B, member 6
R. norvegicus	UniProtKB:Q2UZS7 (Q2UZS7 · IPI00204941 · Dnaja3) · RGD:1306527 (Dnaja3)	DnaJ (Hsp40) homolog, subfamily A, member 3
R. norvegicus	UniProtKB:Q4QR73 · RGD:1310035 (Dnaja4)	DnaJ (Hsp40) homolog, subfamily A, member 4
R. norvegicus	UniProtKB:Q5XIP0 · RGD:1305826 (Dnajb4)	DnaJ (Hsp40) homolog, subfamily B, member 4
R. norvegicus	UniProtKB:Q5YKV6 · RGD:1359131 (Dnajb13)	DnaJ (Hsp40) related, subfamily B, member 13
R. norvegicus	UniProtKB:Q9QZW8 · RGD:708544 (LOC56764)	dnaj-like protein
R. norvegicus	NCBI:XP_221491 · RGD:1565996 (RGD1565996)	similar to DnaJ homolog subfamily B member 6 (Heat shock protein J2)
S. cerevisiae	UniProtKB:P25491 · SGD:S000005008 (YNL064C · MAS5 · YDJ1 · HSP40)	Protein chaperone involved in regulation of the HSP90 and HSP70 functions
S. cerevisiae	UniProtKB:P35191 · SGD:S000001878 (MDJ1 · YFL016C)	Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p
S. cerevisiae	UniProtKB:P25303 · SGD:S000004827 (SCJ1 · YMR214W)	One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins
S. cerevisiae	UniProtKB:P25294 · SGD:S000004952 (SIS1 · YNL007C)	Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p
S. cerevisiae	UniProtKB:P39102 · SGD:S000004080 (YLR090W · XDJ1)	Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p
S. cerevisiae	UniProtKB:P53940 · SGD:S000005021 (YNL077W · APJ1)	Putative chaperone of the HSP40 (DNAJ) family
S. pombe	UniProtKB:O74752 · GeneDB_Spombe:SPBC1734.11 (SPBC1734.11)	DNAJ domain protein Mas5
S. pombe	UniProtKB:P87239 · GeneDB_Spombe:SPCC4G3.14 (mdj1 · SPCC4G3.14)	DNAJ domain protein Mdj1
S. pombe	UniProtKB:Q09912 · GeneDB_Spombe:SPCC830.07c (SPCC830.07c · psi1 · psi)	DNAJ domain protein Psi1
S. pombe	UniProtKB:O94625 · GeneDB_Spombe:SPBC1347.05c (SPBC1347.05c)	DNAJ domain protein Scj1
S. pombe	UniProtKB:O94657 · GeneDB_Spombe:SPBC405.06 (SPBC405.06)	DNAJ protein Xdj1

Protein	Publication	Curator Notes
UniProtKB:P35191 · SGD:S000001878	12215516 Christensen CA, et al. Mitochondrial GFA2 is required for synergid cell death in Arabidopsis. Plant Cell. 2002 Sep;14(9):2215-32.	The A. thaliana protein AT5G48030.1 complements a homologous mutation in S. cerevisiae.
UniProtKB:P35191 · SGD:S000001878	10821188 Lisse T, et al. Functional specificity of the mitochondrial DnaJ protein, Mdj1p, in Saccharomyces cerevisiae. Mol Gen Genet. 2000 Apr;263(3):527-34.	The E. coli protein DnaJ complements a homologous mutation in S. cerevisiae.
UniProtKB:P35191 · SGD:S000001878	9324254 Deloche O, et al. Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli. J Bacteriol. 1997 Oct;179(19):6066-75.	The S. cerevisiae protein MDJ1 complements a homologous mutation in E. coli. This paper describes a biochemical and genetic analysis of yeast Mdj1p, Ssc1p, and Mge1p in E. coli.
UniProtKB:P25491 · SGD:S000005008	11939789 Yan W, et al. Inactivation of the PKR protein kinase and stimulation of mRNA translation by the cellular co-chaperone P58(IPK) does not require J domain function. Biochemistry. 2002 Apr 16;41(15):4938-45.	The H. sapiens/S. cerevisiae protein Q13217 complements a homologous mutation in S. cerevisiae. A chimeric protein in which the human p58IPK J domain replaces the yeast Ydj1p J domain can complement a yeast ydj1 mutant.
UniProtKB:P25294 · SGD:S000004952	11551903 Salmon D, et al. A DnaJ-like protein homologous to the yeast co-chaperone Sis1 (TcJ6p) is involved in initiation of translation in Trypanosoma cruzi. J Biol Chem. 2001 Nov 23;276(47):43970-9.	The T. cruzi protein TcJ6 complements a homologous mutation in S. cerevisiae.
UniProtKB:P25294 · SGD:S000004952	10677504 Krobitsch S, et al. Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1589-94.	The H. sapiens protein Ht (protein ID unknown) was expressed in S. cerevisiae, but complementation was not directly tested. This paper describes the characterization of variant truncated forms of the human Huntington's disease protein expressed in yeast.
UniProtKB:P25491 · SGD:S000005008	9605323 Leng CH, et al. Isolation and characterization of a DnaJ-like protein in rats: the C-terminal 10-kDa domain of hsc70 is not essential for stimulating the ATP-hydrolytic activity of hsc70 by a DnaJ-like protein. Protein Sci. 1998 May;7(5):1186-94.	The R. norvegicus protein RDJ1 complements a homologous mutation in S. cerevisiae. Rat RDJ1 rescues the temperature-sensitive lethality of a yeast ydj1-151 mutant.
UniProtKB:P25491 · SGD:S000005008	15147737 Edkins AL, et al. A Trypanosoma cruzi heat shock protein 40 is able to stimulate the adenosine triphosphate hydrolysis activity of heat shock protein 70 and can substitute for a yeast heat shock protein 40. Int J Biochem Cell Biol. 2004 Aug;36(8):1585-98.	The T. cruzi protein Tcj2 complements a homologous mutation in S. cerevisiae.
UniProtKB:P25491 · SGD:S000005008	16889384 Zhang W, et al. Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins. Biotechnol Prog. 2006 Jul-Aug;22(4):1090-5.	The S. cerevisiae protein YDJ1 was expressed in P. pastoris, but complementation was not directly tested. This paper shows heterologous overexpression of S. cerevisiae YDJ1 in P. pastoris.

Description	Suffix
Sequences in this family	.fasta
mafft aligned Fasta file	.afasta
phyml newick file	.newick
Notung rooted & rearranged newick file	.newick.rooting.0.rearrange.0
Notung Homolog Table	.newick.rooting.0.rearrange.0.homologs.csv

SGD Disease Papers (1)
UniProtKB:P25491 · SGD:S000005008	10859365 Muchowski PJ, et al. (2000) Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils. Proc Natl Acad Sci U S A 97(14):7841-6