This family has 10 members: 2 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Schizosaccharomyces pombe.
| Notung Tree [Applet] | Organism | Protein | AmiGO |
|---|---|---|---|
 D = Duplication Event | Caenorhabditis elegans | UniProtKB:O45069 | |
| Caenorhabditis elegans | WB:WBGene00015702 | ||
| Danio rerio | ZFIN:ZDB-GENE-070410-3 (zgc:136564) | AmiGO | |
| Dictyostelium discoideum | dictyBase:DDB0188074 | ||
| Drosophila melanogaster | FB:FBgn0034614 | ||
| Gallus gallus | RefSeq:XP_001231514 | ||
| Homo sapiens | UniProtKB:Q5T6V5 | AmiGO | |
| Mus musculus | MGI:1917403 | AmiGO | |
| Rattus norvegicus | RGD:1311345 | ||
| Schizosaccharomyces pombe | SPAC589.05c (SPAC589.05c) | AmiGO |
CLUSTAL W (1.83.1) multiple sequence alignment # P-POD
R.norvegicus|RGD:1311345 ------------------------------------------------------------
M.musculus|MGI:1917403 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T6V5 --MDGLLNPRESSKFIAENSRDVFIDSGGVRRVAELLL---AKAAGPELRVEGWKALHEL
G.gallus|RefSeq:XP_001231514 --MEALPSPLESARFIAGRSRDVSVDEEGARKVAESLF---DKASEAAFGLSGWKSLHEL
D.rerio|ZFIN:ZDB-GENE-070410-3 --MEQPLSPRESGRFVSERSRDVFVDEDGVKRVAQMIY---ELRDSDEFTASGWKKMNPL
D.melanogaster|FB:FBgn0034614 ------------------------------------------------------------
S.pombe|SPAC589.05c -----MSRVLQDAEFISLNSNDVKVNKGGCAAVATWIK---EKLDSLGPQFAEWQN-HEL
C.elegans|WB:WBGene00015702 MLIDEVLGPAESGKFIVEHGNLVKINQAGVRKVAEHIL---GAAKDGSLKEALFLS-PEL
C.elegans|UniProtKB:O45069 MLIDEVLGPAESGKFIVEHGNLVKINQAGVRKVAEHIL---GAAKDGSLKEALFLS-PEL
D.discoideum|dictyBase:DDB0188074 --MNPLTLVRETTAWVSGLSKHVKINNEALDKECEDFLNKHKIKAHKEIWADNWFHYCDI
R.norvegicus|RGD:1311345 ------------------------------------------------------------
M.musculus|MGI:1917403 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T6V5 NPRAAD----EAAVNWVFVTDTLNFSFWSEQDEHKC-------VVRYRGKTYSGYWSLCA
G.gallus|RefSeq:XP_001231514 NPRAAS----EEAVSWVFLVDTLNFSFWSESAEQNA-------WCATRGRAYSGYWALCA
D.rerio|ZFIN:ZDB-GENE-070410-3 APSPDS----DDAINWVFVTDTMNFSFWPEKEDEQC-------EVVCRGDTYRGYMSLCA
D.melanogaster|FB:FBgn0034614 ------------------------------------------------------------
S.pombe|SPAC589.05c HPKTRD----VSTLDWIFLVDILNFSFWSDVDVEDSGKHSKRFSIEYKGKLYTGYWSLCA
C.elegans|WB:WBGene00015702 HPKSGD----KDAVQWVLLVDTINFSFWPDEGDHYD--------VSWGGKAYTGYFAACA
C.elegans|UniProtKB:O45069 HPKSGD----KDAVQWVLLVDTINFSFWPDEGDHYD--------VSWGGKAYTGYFAACA
D.discoideum|dictyBase:DDB0188074 DIENKESTFTELTAKYILVLDTLNFCFWPDSEFEYH-------------HLARGLKNALI
R.norvegicus|RGD:1311345 ------------------------------------------------------------
M.musculus|MGI:1917403 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T6V5 AVNRALDEGIPITSASYYA---TVTLDQVRNILRSDTDVSMPLVEERHRILNETGKILLE
G.gallus|RefSeq:XP_001231514 AVNRALDDGIPITSASYYA---TMTLDQVRQVFRSDTEVPMPLLEERHRVLNESGTVLLE
D.rerio|ZFIN:ZDB-GENE-070410-3 AITRAMDEGVPITNPSFFS---EISESELAKVLRSDSPTPMPMLRERHQALTEAGRVLVQ
D.melanogaster|FB:FBgn0034614 ------------------------------------------------------------
S.pombe|SPAC589.05c AINKALDAGIPITSPAFYADEKQCPDTLIASVFDSATVEKIPLLEERIRIMRASGRVLVD
C.elegans|WB:WBGene00015702 AVNKAIAAGIPVLSAEWMK---NVGREEIDRIFKSDSGHSIPLLDDRVKAINDSGKVLLE
C.elegans|UniProtKB:O45069 AVNKAIAAGIPVLSAEWMK---NVGREEIDRIFKSDSGHSIPLLDDRVKAINDSGKVLLE
D.discoideum|dictyBase:DDB0188074 ANPKCFDADQLIK--------------VTSETIHQWFGKDLPNTSERVRLIREVGTVLIE
R.norvegicus|RGD:1311345 ------------------------------------------------------------
M.musculus|MGI:1917403 --------------------MQLIVENFPSYRDEAEFEGKRIAFYKRAQILVADTWSVLE
H.sapiens|UniProtKB:Q5T6V5 KFGGSFLNCVRESENSAQKLMHLVVESFPSYRDVTLFEGKRVSFYKRAQILVADTWSVLE
G.gallus|RefSeq:XP_001231514 KFGGSFLTCVKMSENSAQKLLRLVVENFPSYRDEAVFEKKKVSFYKRAQILVADTWSVLE
D.rerio|ZFIN:ZDB-GENE-070410-3 -HGGSFRTFMSRCENDAQKMVQHIVENIPSYRDEATYEGKRISFYKRAQILVADFWGIME
D.melanogaster|FB:FBgn0034614 ------------------------------------------------------------
S.pombe|SPAC589.05c SYHGSYCGLLKKCHNQAQRLIKLLLADFPDFRDVSVYKGRECYMLKRAQILVAETWACFQ
C.elegans|WB:WBGene00015702 KFDGQFYNCVIKSEKSAQTLLKLIVENFVSFRDFAEFNGQKVSLLKRAQILVADVYGSLQ
C.elegans|UniProtKB:O45069 KFDGQFYNCVIKSEKSAQTLLKLIVENFVSFRDFAEFNGQKVSLLKRAQILVADVYGSLQ
D.discoideum|dictyBase:DDB0188074 YFNGSIKEMILSANNKASVLVDLVTKYFWGFRDSAIYKGKQVFFYKRAQIFVGDLWGAYQ
R.norvegicus|RGD:1311345 ----------------------------------------------MLLNGDKQEVEIRG
M.musculus|MGI:1917403 GKGDG-CFEDISSITMFADYRLPQILVYLGALKYSDELLKKLLKGEMLLNGDKQEVEIRG
H.sapiens|UniProtKB:Q5T6V5 GKGDG-CFKDISSITMFADYRLPQVLAHLGALKYSDDLLKKLLKGEMLSYGDRQEVEIRG
G.gallus|RefSeq:XP_001231514 GKGDG-FFGDISSLTIFADYRIPQVLVHLKAMKYSEDLMKKLREGTVFKSGDREEVEIRG
D.rerio|ZFIN:ZDB-GENE-070410-3 ARGEG-NIPNLDYLTMFADYRVPQGLVYLGALRYSDALMETLKNGELLSSGERREVEIRG
D.melanogaster|FB:FBgn0034614 ---------------MFADYRIPQVLVHFGSLEYTSELMEFLKTDTILENGDPREVEIRG
S.pombe|SPAC589.05c GQNYG-RFDDIDSITMFADYRVPQILWQLGCLSYSSDFKKRLLKNELIAHNDPMEIEMRG
C.elegans|WB:WBGene00015702 GHDDAGNFKDITTITMFADYRVPQALAYLGALDYSEELLSQLGEGKRLENGSKAEVELRG
C.elegans|UniProtKB:O45069 GHDDAGNFKDITTITMFADYRVPQALAYLGALDYSEELLSQLGEGKRLENGSKAEVELRG
D.discoideum|dictyBase:DDB0188074 GRGLG-KFDDIKQLTMFADYRVPQILEELKVIEYSPELKEMIKNKVEIPVGSEMELEIRA
: .. *:*:*.
R.norvegicus|RGD:1311345 CSIWCVELIRDCLVELLEKR-GESPPVEVNAILLDYHLWDYAREHRDG---------MKG
M.musculus|MGI:1917403 CSIWCVELIRDRLLELLEK--GENSPVEINSVLLDYHLWDYAREHRED---------MKG
H.sapiens|UniProtKB:Q5T6V5 CSLWCVELIRDCLLELIEQK-GEKPNGEINSILLDYYLWDYAHDHRED---------MKG
G.gallus|RefSeq:XP_001231514 CSIWCCTLICKHLLDLYEKK-GQDMRDQINAVLLDYYLWDYARDHRED---------MKD
D.rerio|ZFIN:ZDB-GENE-070410-3 CSIWCVEKIRQHLWKLVEEK-DGKS-CHINSALIDFYLWPYAKKHHKE---------MAH
D.melanogaster|FB:FBgn0034614 ASIYIIEQVRDAVVKILKEQHPEISLDNVNSIVIDQYLWDYRRRHNAD---------LEH
S.pombe|SPAC589.05c CSIWAVEKILQN----INRK-------DVNAITIDFFLWDLAKEWQAKGYKPSTQVDEVT
C.elegans|WB:WBGene00015702 ASIAVCDEIVAKMNELRETDPRFSDVCEVNAMEVDVYVWGYRRLYAAD--------VEKK
C.elegans|UniProtKB:O45069 ASIAVCDEIVAKMNELRETDPRFSDVCEVNAMEVDVYVWGYRRLYAAD--------VEKK
D.discoideum|dictyBase:DDB0188074 VTVHVVEKMRDYFN---------KGHCELLALEIDWMLWGRGEAMLDK-----------L
:: : .: : :* :* .
R.norvegicus|RGD:1311345 VPFHRTRCIYY
M.musculus|MGI:1917403 VPFHRTRCIYY
H.sapiens|UniProtKB:Q5T6V5 IPFHRIRCIYY
G.gallus|RefSeq:XP_001231514 IPFHRVRCIYY
D.rerio|ZFIN:ZDB-GENE-070410-3 IPIHHTRCIYY
D.melanogaster|FB:FBgn0034614 IPFHKVLSIYY
S.pombe|SPAC589.05c IPCIRVRSIYY
C.elegans|WB:WBGene00015702 VPFHRTRCIYY
C.elegans|UniProtKB:O45069 VPFHRTRCIYY
D.discoideum|dictyBase:DDB0188074 PPHHRTLTIFY
* : *:*
| Program | Link |
|---|---|
| ClustalW alignment file | .alnp |
| ClustalW dendrogram file | .dnd |
| Notung tree file: rearranged | .jtt.rooting.0.rearrange.0 |
| Phylip amino acid sequence Maximum Likelihood method | .jtt |
| Sequences in this family (FASTA) | ORTHOMCL5552.fa |