This family has 12 members: 1 Arabidopsis thaliana, 3 Caenorhabditis elegans, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
| Notung Tree [Applet] | Organism | Protein | AmiGO |
|---|---|---|---|
 D = Duplication Event | Arabidopsis thaliana | TAIR:gene:2161916 (AT5G63220.1) | AmiGO |
| Caenorhabditis elegans | UniProtKB:Q19824 (Q19824_CAEEL) | AmiGO | |
| Caenorhabditis elegans | WB:WBGene00017825 (F26F4.1) | AmiGO | |
| Caenorhabditis elegans | WP:WB:CE01257 | ||
| Dictyostelium discoideum | dictyBase:DDB0218329 | ||
| Drosophila melanogaster | FB:FBgn0086605 | ||
| Gallus gallus | UniProtKB:Q5ZKG8 | ||
| Homo sapiens | UniProtKB:Q7L5D6 (CG020_HUMAN) | AmiGO | |
| Mus musculus | MGI:1914854 | AmiGO | |
| Rattus norvegicus | RGD:1311660 (RGD1311660_predicted) | AmiGO | |
| Saccharomyces cerevisiae | SGD:S000005690 (YOR164C) | AmiGO | |
| Schizosaccharomyces pombe | SPCC1672.12c (SPCC1672.12c) | AmiGO |
CLUSTAL W (1.83.1) multiple sequence alignment # P-POD
C.elegans|WP:WB:CE01257 ------------------------------------------------------------
C.elegans|WB:WBGene00017825 ------------------------------------------------------------
C.elegans|UniProtKB:Q19824 ------------------------------------------------------------
R.norvegicus|RGD:1311660 MYKVLAGSFADPSGAWPRAAKAILLGSARITCGPRRARPHAVPRGHRRRSAAAAGTEAAR
M.musculus|MGI:1914854 ------------------------------------------------------------
H.sapiens|UniProtKB:Q7L5D6 ------------------------------------------------------------
G.gallus|UniProtKB:Q5ZKG8 ------------------------------------------------------------
D.melanogaster|FB:FBgn0086605 ------------------------------------------------------------
D.discoideum|dictyBase:DDB0218329 ------------------------------------------------------------
A.thaliana|TAIR:gene:2161916 ------------------------------------------------------------
S.pombe|SPCC1672.12c ------------------------------------------------------------
S.cerevisiae|SGD:S000005690 ------------------------------------------------------------
C.elegans|WP:WB:CE01257 -----------------------------------------MDATTLSRLSEFEKEKKFY
C.elegans|WB:WBGene00017825 -----------------------------------------MDATTLSRLSEFEKEKKFY
C.elegans|UniProtKB:Q19824 -----------------------------------------MDATTLSRLSEFEKEKKFY
R.norvegicus|RGD:1311660 RRRPRLRQRQLCAERRPMAAAAAAAAMAEQEGARNGARNRGGVQRVEGKLRASVEKGDYY
M.musculus|MGI:1914854 --------------------MAAAAAMAEQEGARNGARNRGGVQRVEGKLRASVEKGDYY
H.sapiens|UniProtKB:Q7L5D6 --------------------MAAAAAMAEQESARNGGRNRGGVQRVEGKLRASVEKGDYY
G.gallus|UniProtKB:Q5ZKG8 --------------------MAAAIMAAEQEAAKGGGRNRGGVQRVEGKLRASVEKGDYY
D.melanogaster|FB:FBgn0086605 --------------------MSAAETGPIASGSAVSTGQRG-VSRVLAKLSQSLAGGEFY
D.discoideum|dictyBase:DDB0218329 -----------------------------------------MAERVLANLEAKFTEGNYY
A.thaliana|TAIR:gene:2161916 ------------------------------MSRERIKRELPPVQEHIDKLRKVIEEGNYY
S.pombe|SPCC1672.12c ------------------------------------------MDAKIKRAEGRLRE-DPY
S.cerevisiae|SGD:S000005690 ------------------------------MVPAESNAVQAKLAKTLQRFENKIKAGDYY
. . *
C.elegans|WP:WB:CE01257 DALQFYRTKVTRSFRLKNANEVAIPLVKHALEFFFREKQYQCAIDITTQYAECLSK--NN
C.elegans|WB:WBGene00017825 DALQFYRTKVTRSFRLKNANEVAIPLVKHALEFFFREKQYQCAIDITTQYAECLSK--NN
C.elegans|UniProtKB:Q19824 DALQFYRTKVTRSFRLKNANEVAIPLVKHALEFFFREKQYQCAIDITTQYAECLSK--NN
R.norvegicus|RGD:1311660 EAHQMYRTLFFR-YMSQSKHAEARELMYSGALLFFSHGQQNSAADLSMLVLESLEK--AE
M.musculus|MGI:1914854 EAHQMYRTLFFR-YMSQSKHAEARELMYSGALLFFSHGQQNSAADLSMLVLESLEK--AE
H.sapiens|UniProtKB:Q7L5D6 EAHQMYRTLFFR-YMSQSKHTEARELMYSGALLFFSHGQQNSAADLSMLVLESLEK--AE
G.gallus|UniProtKB:Q5ZKG8 EAHQMYRTLFFR-YMSQGKYVEARELMYSGALLFFSHNQQNSAADLSMLVLESLEK--SD
D.melanogaster|FB:FBgn0086605 EAHMMYRTLYFR-YTAQKRYQDCLELLFDGAQQLIAKEQESSAADLCLLLVDTLEKRGPQ
D.discoideum|dictyBase:DDB0218329 DILQSYKALYNR-FSTQKKYKETVTLLESGCNKFLEYKQWNCAADLAKLLIECYKN--FK
A.thaliana|TAIR:gene:2161916 GALQMYKSISAR-YVTAQRFSEALDILFSGACIELEHGLVNCGADLAILFVDTLVK--AK
S.pombe|SPCC1672.12c EGHQMLRTLVNR-QVKAKKHDDAVALLYSGAKTLFEIEQTGSAADLAIYMLDVYEK----
S.cerevisiae|SGD:S000005690 EAHQTLRTIANR-YVRSKSYEHAIELISQGALSFLKAKQGGSGTDLIFYLLEVYDL--AE
:: * :: . : .. *: :
C.elegans|WP:WB:CE01257 VDLGEEAFNILADSVSKFANFAEIEN---------------EAGNSEPEQLLNTARCKCV
C.elegans|WB:WBGene00017825 VDLGEEAFNILADSVSKFANFAEIEN---------------EAGNSEPEQLLNTARCKCV
C.elegans|UniProtKB:Q19824 VDLGEEAFNILADSVSKFANFAEIEN---------------EAGNSEPEQLLNTARCKCV
R.norvegicus|RGD:1311660 VDVADELLEN---LAKVFSLMD----------------------------PNSPERVAFV
M.musculus|MGI:1914854 VDVADELLEN---LAKVFSLMD----------------------------PNSPERVAFV
H.sapiens|UniProtKB:Q7L5D6 VEVADELLEN---LAKVFSLMD----------------------------PNSPERVTFV
G.gallus|UniProtKB:Q5ZKG8 AKVTDDLLEN---LAKLFSLMD----------------------------PNSPERVAFV
D.melanogaster|FB:FBgn0086605 AEDTDNFLWVPR-LGALIRGLN----------------------------SATVERETLI
D.discoideum|dictyBase:DDB0218329 IQYSDESKEP---IIKIFKNFK------------------------GECAGKIS----FM
A.thaliana|TAIR:gene:2161916 SPCNDETLDR---IRCIFKLFPRVPVPPHLVDVSDDEDVQNLQESLGEARSRVENLTSFL
S.pombe|SPCC1672.12c -ASYAASLDNKARALTLLGLFP----------------------------AEEGARKQYV
S.cerevisiae|SGD:S000005690 VKVDDISVAR---LVRLIAELD----------------------------PSEPNLKDVI
: : :
C.elegans|WP:WB:CE01257 DLAIQWTKQKATTPIEKKYGSAAFHTVLAKKLVAVD---HVELAKNHFLLSDDFKSFANF
C.elegans|WB:WBGene00017825 DLAIQWTKQKATTPIEKKYGSAAFHTVLAKKLVAVD---HVELAKNHFLLSDDFKSFANF
C.elegans|UniProtKB:Q19824 DLAIQWTKQKATTPIEKKYGSAAFHTVLAKKLVAVD---HVELAKNHFLLSDDFKSFANF
R.norvegicus|RGD:1311660 SRALKWSSGGSG-----KLGHPRLHQLLALTLWKEQ---NYCESRYHFLHSTDGEGCANM
M.musculus|MGI:1914854 SRALKWSSGGSG-----KLGHPRLHQLLALTLWKEQ---NYCESRYHFLHSSDGEGCANM
H.sapiens|UniProtKB:Q7L5D6 SRALKWSSGGSG-----KLGHPRLHQLLALTLWKEQ---NYCESRYHFLHSADGEGCANM
G.gallus|UniProtKB:Q5ZKG8 SRALKWSSGGSG-----KLGHPKLHQLLAITLWK------------------DGEGCANM
D.melanogaster|FB:FBgn0086605 QRTIKWSTALHG-----QYGHPVLHKLIAHVFWTEG---NIESARHHYLLCQDGSLCGRV
D.discoideum|dictyBase:DDB0218329 RDAIEWSSKNGGD----SKGSEEFHTLLAITLSEEG---DYIDAQKHFIFGNDYFSFCEM
A.thaliana|TAIR:gene:2161916 RAAIKWSAEFGGP----RTGYPELHAMLGDYLYTECPELDMVRISRHFVRAEDPEKFASM
S.pombe|SPCC1672.12c KRLLEWSKSAGP------QGDKDVHFAVATMFVKWK---EPASAEKHFVLGNEKSARAYG
S.cerevisiae|SGD:S000005690 TGMNNWSIKFSEY----KFGDPYLHNTIGSKLLEGD---FVYEAERYFMLGTHDSMIKYV
:*: * .* :. : .
C.elegans|WP:WB:CE01257 LHQEYESFKQKESEP---EVIIVEAVFQSLCLDRFPFAVSLFTEYVAPAK------YP--
C.elegans|WB:WBGene00017825 LHQEYESFKQKESEP---EVIIVEAVFQSLCLDRFPFAVSLFTEYVAPAK------YP--
C.elegans|UniProtKB:Q19824 LHQEYESFKQKESEP---EVIIVEAVFQSLCLDRFPFAVSLFTEYVAPAK------YP--
R.norvegicus|RGD:1311660 L-VEYSTARGFRSEV---DMFVAQAVLQFLCLKNKNSALVVFTTYTQKHPSIEDGP-P--
M.musculus|MGI:1914854 L-VEYSTARGFRSEV---DMFVAQAVLQFLCLKNKNSALVVFTTYTQKHPSIEDGP-P--
H.sapiens|UniProtKB:Q7L5D6 L-VEYSTSRGFRSEV---DMFVAQAVLQFLCLKNKSSASVVFTTYTQKHPSIEDGP-P--
G.gallus|UniProtKB:Q5ZKG8 L-VEYSSSRGYRSEV---DMFVAQAVLQFLCLKNKTSASVVFTTYTQKHPSIEKGP-P--
D.melanogaster|FB:FBgn0086605 L-IEISQSRGFQGEM---DLFLVQAVLQQLSLKDRKTAEDTFTEYTRYHAKLLKHEFP--
D.discoideum|dictyBase:DDB0218329 L-KNWTE-DVDEEEK---DLYITRAIFGLLCLKKLKQASDLYNLFTTKVIKGDP------
A.thaliana|TAIR:gene:2161916 L-VNFMG-RCYPGED---DLAIARAVLMYLSMGNMKDANFMMDEIKKQAETKNPEL----
S.pombe|SPCC1672.12c ETMYYWFTSDSSISP---DTFAGRPVLNYLLAENLISAWNSLETFTKHFTKSNAPDVENM
S.cerevisiae|SGD:S000005690 DLLWDWLCQVDDIEDSTVAEFFSRLVFNYLFISNISFAHESKDIFLERFIEKFHPKYEKI
. . :: * *
C.elegans|WP:WB:CE01257 ----------FTKPLLNFQHILFDVIETENQPQYSELTSSYQTELKRSLAFIGYLTRIGK
C.elegans|WB:WBGene00017825 ----------FTKPLLNFQHILFDVIETENQPQYSELTSSYQTELKRSLAFIGYLTRIGK
C.elegans|UniProtKB:Q19824 ----------FTKPLLNFQHILFDVIETENQPQYSELTSSYQTELKRSLAFIGYLTRIGK
R.norvegicus|RGD:1311660 ----------FVQPLLNFIWFLLLAVDGGKLAVFTVLCEQYQPSLRRDPMYNEYLDRIGQ
M.musculus|MGI:1914854 ----------FVQPLLNFIWFLLLAVDGGKLAVFTVLCEQYQPSLRRDPMYNEYLDRIGQ
H.sapiens|UniProtKB:Q7L5D6 ----------FVEPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLRRDPMYNEYLDRIGQ
G.gallus|UniProtKB:Q5ZKG8 ----------FVQPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLKRDPMYNEYLDRIGQ
D.melanogaster|FB:FBgn0086605 ----------YKEPLVNFLYFLFRLIDAKRVAGFRALRKLYDPSLKRDTSFLKYVAKIGV
D.discoideum|dictyBase:DDB0218329 ------------SPLLNFDRFLLLTLERDALPLFNLLRQKYERSLKRDPQFKKFLDQIAN
A.thaliana|TAIR:gene:2161916 ----------SESDLIQFISYLLETLQRDALPLFNMLRVKYKSSIDRDQLLNELLDEIAE
S.pombe|SPCC1672.12c SFDGKDFPVFKEYPQMNFLHLLIFTAYRKDKETYLSLVQKYP----KKQDWEAALAKIEE
S.cerevisiae|SGD:S000005690 DKNGYEIVFFEDYSDLNFLQLLLITCQTKDKSYFLNLKNHYLD---FSQAYKSELEFLGQ
::* *: : * * . : :
C.elegans|WP:WB:CE01257 LYFGIRDNQCMSG--GLGGLFSGLLGGQKEEETATSHITSRTPARQKPAAMSQPSPFGPF
C.elegans|WB:WBGene00017825 LYFGIRDNQCMSG--GLGGLFSGLLGGQKEEETATSHITSRTPARQKPAAMSQPSPFGPF
C.elegans|UniProtKB:Q19824 LYFGIRDNQCMSG--GLGGLFSGLLGGQKEEETATSHITSRTPARQKPAAMSQPSPFGPF
R.norvegicus|RGD:1311660 LFFGVPPKQTSS----YGGLLGNLLS----------------------------SLMGSS
M.musculus|MGI:1914854 LFFGVPPKQTSS----YGGLLGNLLS----------------------------SLMGSS
H.sapiens|UniProtKB:Q7L5D6 LFFGVPPKQTSS----YGGLLGNLLT----------------------------SLMGSS
G.gallus|UniProtKB:Q5ZKG8 LFFGVPPKQTSS----YGGLLGNLLN----------------------------SLMGTG
D.melanogaster|FB:FBgn0086605 LYFDEHPEAAHSGPPGLGGMFGDIFN----------------------------RLMAGF
D.discoideum|dictyBase:DDB0218329 IFYNVPIQSGGG----LSGMLSNLLS----------------------------GFGGGM
A.thaliana|TAIR:gene:2161916 RFYGVQRKNP------LQGMFGDIFK----------------------------MMG---
S.pombe|SPCC1672.12c IYFGIRPVSNQP------NILANLMS----------------------------SLFSGP
S.cerevisiae|SGD:S000005690 EYFNIVAPKQTN-------FLQDMMS----------------------------GFLGGS
::. :: .::
C.elegans|WP:WB:CE01257 GALAGAPAPAPVPKKIQKVEMEEDLD
C.elegans|WB:WBGene00017825 GALAGAPAPAPVPKKIQKVEMEEDLD
C.elegans|UniProtKB:Q19824 GALAGAPAPAPVPKKIQKVEMEEDLD
R.norvegicus|RGD:1311660 EQEEGEESQD----DSSPIELD----
M.musculus|MGI:1914854 EQEEGEESQD----DSSPIELD----
H.sapiens|UniProtKB:Q7L5D6 EQEDGEESPS----DGSPIELD----
G.gallus|UniProtKB:Q5ZKG8 EDDDTEDGQE----DSSPIELD----
D.melanogaster|FB:FBgn0086605 EEDDADDHDTTLRRQNENNELE----
D.discoideum|dictyBase:DDB0218329 GMGGNSSGGGLASMEVDGPTIEDEMD
A.thaliana|TAIR:gene:2161916 --------------------------
S.pombe|SPCC1672.12c PAATN------------QLDLE----
S.cerevisiae|SGD:S000005690 K-------------------------
| Program | Link |
|---|---|
| ClustalW alignment file | .alnp |
| ClustalW dendrogram file | .dnd |
| Notung tree file: rearranged | .jtt.rooting.0.rearrange.0 |
| Phylip amino acid sequence Maximum Likelihood method | .jtt |
| Sequences in this family (FASTA) | ORTHOMCL4429.fa |