This family has 14 members: 2 Arabidopsis thaliana, 3 Caenorhabditis elegans, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 1 Gallus gallus, 1 Homo sapiens, 1 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
| Notung Tree [Applet] | Organism | Protein | AmiGO |
|---|---|---|---|
 D = Duplication Event | Arabidopsis thaliana | TAIR:gene:1006229452 (AT5G19150.2) | AmiGO |
| Arabidopsis thaliana | TAIR:gene:2182146 (AT5G19150.1) | AmiGO | |
| Caenorhabditis elegans | UniProtKB:P32740 | ||
| Caenorhabditis elegans | WB:WBGene00011298 | ||
| Caenorhabditis elegans | WP:WB:CE23917 | ||
| Dictyostelium discoideum | dictyBase:DDB0189092 | ||
| Drosophila melanogaster | FB:FBgn0036848 | ||
| Escherichia coli | P31806 | AmiGO | |
| Gallus gallus | RefSeq:XP_416954 | ||
| Homo sapiens | UniProtKB:Q5T9X3 (Q5T9X3_HUMAN) | ||
| Mus musculus | MGI:1913353 (0710008K08Rik) | ||
| Rattus norvegicus | RGD:1562691 | ||
| Saccharomyces cerevisiae | SGD:S000001634 (YKL151C) | AmiGO | |
| Schizosaccharomyces pombe | SPCC61.03 (SPCC61.03) | AmiGO |
CLUSTAL W (1.83.1) multiple sequence alignment # P-POD
S.cerevisiae|SGD:S000001634 ------------------------------------------------------------
S.pombe|SPCC61.03 ------------------------------------------------------------
A.thaliana|TAIR:gene:2182146 ------------------------------------------------------------
A.thaliana|TAIR:gene:1006229452 ------------------------------------------------------------
D.discoideum|dictyBase:DDB0189092 ------------------------------------------------------------
R.norvegicus|RGD:1562691 ------------------------------------------------------------
M.musculus|MGI:1913353 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T9X3 ------------------------------------------------------------
G.gallus|RefSeq:XP_416954 MDFLLPVGIQRGFLWSDLETRALLEIWGEADVQSALDGNFRNSHVYRDVACRLAELGFER
D.melanogaster|FB:FBgn0036848 ------------------------------------------------------------
C.elegans|WP:WB:CE23917 ------------------------------------------------------------
C.elegans|WB:WBGene00011298 ------------------------------------------------------------
C.elegans|UniProtKB:P32740 ------------------------------------------------------------
E.coli|P31806 ------------------------------------------------------------
S.cerevisiae|SGD:S000001634 ------------------------------------------------------------
S.pombe|SPCC61.03 ------------------------------------------------------------
A.thaliana|TAIR:gene:2182146 ------------------------------------------------------------
A.thaliana|TAIR:gene:1006229452 ------------------------------------------------------------
D.discoideum|dictyBase:DDB0189092 ------------------------------------------------------------
R.norvegicus|RGD:1562691 ------------------------------------------------------------
M.musculus|MGI:1913353 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T9X3 ------------------------------------------------------------
G.gallus|RefSeq:XP_416954 TPEQCRIRIKGLKRQYYQARDGLKKNGHARKICKYYDEMDRILSCRGGPDGAPEPPPPLP
D.melanogaster|FB:FBgn0036848 ------------------------------------------------------------
C.elegans|WP:WB:CE23917 ------------------------------------------------------------
C.elegans|WB:WBGene00011298 ------------------------------------------------------------
C.elegans|UniProtKB:P32740 ------------------------------------------------------------
E.coli|P31806 --------------------------------------MTDHTMKKNPVSIPHTVWYADD
S.cerevisiae|SGD:S000001634 ------------------------------------------------------------
S.pombe|SPCC61.03 ------------------------------------------------------------
A.thaliana|TAIR:gene:2182146 ------------------------------------------------------------
A.thaliana|TAIR:gene:1006229452 ------------------------------------------------------------
D.discoideum|dictyBase:DDB0189092 ------------------------------------------------------------
R.norvegicus|RGD:1562691 ------------------------------------------------------------
M.musculus|MGI:1913353 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T9X3 ------------------------------------------------------------
G.gallus|RefSeq:XP_416954 DGPQPLGGPPSPGALHNGRENDPEADEDAGLESPRDNFAEDSGECSSYAERPIKVECPPF
D.melanogaster|FB:FBgn0036848 ------------------------------------------------------------
C.elegans|WP:WB:CE23917 ------------------------------------------------------------
C.elegans|WB:WBGene00011298 ------------------------------------------------------------
C.elegans|UniProtKB:P32740 ------------------------------------------------------------
E.coli|P31806 IRRGEREAADVLGLTLYELMLRAGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARL
S.cerevisiae|SGD:S000001634 ------------------------------------------------------------
S.pombe|SPCC61.03 ------------------------------------------------------------
A.thaliana|TAIR:gene:2182146 ------------------------------------------------------------
A.thaliana|TAIR:gene:1006229452 ------------------------------------------------------------
D.discoideum|dictyBase:DDB0189092 ------------------------------------------------------------
R.norvegicus|RGD:1562691 ------------------------------------------------------------
M.musculus|MGI:1913353 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5T9X3 ------------------------------------------------------------
G.gallus|RefSeq:XP_416954 AIPVPPGDGFKEMSAPTVTPPLTQPKRSKKRHANLTLDKMMEKFLQQSVDTEEKFYRYEE
D.melanogaster|FB:FBgn0036848 ------------------------------------------------------------
C.elegans|WP:WB:CE23917 ------------------------------------------------------------
C.elegans|WB:WBGene00011298 ------------------------------------------------------------
C.elegans|UniProtKB:P32740 ------------------------------------------------------------
E.coli|P31806 AKAVGIEVTLLAQESDKPLPEEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGL
S.cerevisiae|SGD:S000001634 ------------------------------------------------------------
S.pombe|SPCC61.03 ------------------------------------------------------------
A.thaliana|TAIR:gene:2182146 ------------------MLVKPSIISGLVRLTSHSPSSSSSVLRRQ-------------
A.thaliana|TAIR:gene:1006229452 ------------------MLVKPSIISGLVRLTSHSPSSSSSVLRRQ-------------
D.discoideum|dictyBase:DDB0189092 ------------------------------------------------------------
R.norvegicus|RGD:1562691 MGIRCVAIRACGGGKIDTGVPRMAVCPYGAAAVVMALLSAAIAFHCS-------------
M.musculus|MGI:1913353 ----------------------MAVHACGAAAAVVALLSAAIALQWS-------------
H.sapiens|UniProtKB:Q5T9X3 ------------------MVTRAGAGTAVAGAVVVALLSAALALYGP-------------
G.gallus|RefSeq:XP_416954 QRLKIEDKRREAEHARELQMLQMLGQMLSGISSTVSQRAQSIPTSPPQRANHRSYGDNFN
D.melanogaster|FB:FBgn0036848 ------------------------------------------------------------
C.elegans|WP:WB:CE23917 ------------------------------------------------------------
C.elegans|WB:WBGene00011298 ------------------------------------------------------------
C.elegans|UniProtKB:P32740 ------------------------------------------------------------
E.coli|P31806 RQAPRESISQLIDHANSHPAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLT
S.cerevisiae|SGD:S000001634 ---------------------MLAELSHRELIKLAQKRCIPPLLPKFHKGQSGGRVCIIG
S.pombe|SPCC61.03 ---------------------MTSGSPKITNLLTRVKRIIPPLLDTFHKGQAG-RVGVFG
A.thaliana|TAIR:gene:2182146 --------EFLVRTLCGSPIIRAMSSTSEADAESVLRTVTPSLDLKRHKGQAG-KIAVIG
A.thaliana|TAIR:gene:1006229452 --------EFLVRTLCGSPIIRAMSSTSEADAESVLRTVTPSLDLKRHKGQAG-KIAVIG
D.discoideum|dictyBase:DDB0189092 ----------------------------MTHLIDLFKPMIPSLLNNLHKGQSG-RIAIMG
R.norvegicus|RGD:1562691 --------PLLAVLQRALSLHTAHATKDMDNLFQLVRNIVPALTSKKHKGQDG-RIGIVG
M.musculus|MGI:1913353 --------PLYAVLQRALSLHTAHATKDMENLFQLVRNIVPALTSKKHKGQDG-RIGIVG
H.sapiens|UniProtKB:Q5T9X3 --------PLDAVLERAFSLRKAHSIKDMENTLQLVRNIIPPLSSTKHKGQDG-RIGVVG
G.gallus|RefSeq:XP_416954 YNAMTAALSPPIVIERSFSLHRNHTLKDMENIFQLVRNVIPPLTGKRHKGQDG-RIGIVG
D.melanogaster|FB:FBgn0036848 ------------------MAAVSDIPVHLPKLLALFKTVVPKLVNNKHKGQYG-RIGVIG
C.elegans|WP:WB:CE23917 --------------------------------MDHFIKLLPKLTPHLRKGDCG-KMGVIG
C.elegans|WB:WBGene00011298 --------------------------------MDHFIKLLPKLTPHLRKGDCG-KMGVIG
C.elegans|UniProtKB:P32740 --------------------------------MDHFIKLLPKLTPHLRKGDCG-KMGVIG
E.coli|P31806 GKARDVTGQLHFDSLGLDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHG-RLVIIG
:**: * :: :.*
S.cerevisiae|SGD:S000001634 GCEDYTGAPYFSANATALMGCDLTHVICEYN--AGTVIKSYTPNLMVHPYLRMSN-----
S.pombe|SPCC61.03 GCQHYTGAPYYSSMSSMLFGSDQSHIFCEKE--AANVIKSYSPDLIVHPFLREKDK----
A.thaliana|TAIR:gene:2182146 GCREYTGAPYFAAISALKIGADLSHVFCTKD--AAPVIKSYSPELIVHPVLEESYSISQL
A.thaliana|TAIR:gene:1006229452 GCREYTGAPYFAAISALKIGADLSHVFCTKD--AAPVIKSYSPELIVHPVLEESYSISQL
D.discoideum|dictyBase:DDB0189092 GSKEYTGAPFFSGISSLKIGSDICHIFAPTEGGTATALKTMSPDLIVHPI----------
R.norvegicus|RGD:1562691 GCQEYTGAPYFAGISALKVGADLTHVFCARE--AAPVIKSYSPELIVHPVLD--------
M.musculus|MGI:1913353 GCQEYTGAPYFAGISALKVGADLTHVFCARE--AAPVIKSYSPELIVHPVLD--------
H.sapiens|UniProtKB:Q5T9X3 GCQEYTGAPYFAAISALKVGADLSHVFCASA--AAPVIKAYSPELIVHPVLD--------
G.gallus|RefSeq:XP_416954 GCREYTGAPYFAAITALKVGADLSHVFCTKD--AATVIKSYSPELIVHPVLD--------
D.melanogaster|FB:FBgn0036848 GSLEYTGAPYFAAISSIRVGADLAHVFCHSN--ASAIIKSYSPDLIVHPVLD--------
C.elegans|WP:WB:CE23917 GSLEYTGAPYFAASSASRLGADLIHIFCDPD--AAQVIKGYSPDLIVHPGMT--------
C.elegans|WB:WBGene00011298 GSLEYTGAPYFAASSASRLGADLIHIFCDPD--AAQVIKGYSPDLIVHPGMT--------
C.elegans|UniProtKB:P32740 GSLEYTGAPYFAASSASRLGADLIHIFCDPD--AAQVIKGYSPDLIVHPGMT--------
E.coli|P31806 GDHGTAGAIRMTGEAALRAGAGLVRVLTRSE--NIAPLLTARPELMVHELT---------
* :** :. :: *.. ::: : *:*:**
S.cerevisiae|SGD:S000001634 --TKLDVDMDEQRKKINSLLDRIHVVVIGPGLGRDPLMLKSIKDIIRYILEKHEGKIPLV
S.pombe|SPCC61.03 --AGPEDSVDKCFELIKPMMGRLHAIVIGPGLGRDEWMQEIMAKVIEYARKN---DMPMV
A.thaliana|TAIR:gene:2182146 SEEDKREVQDKVLGEVGKWMERFDCLVIGPGLGRDPFLLECVSIIMLLAKKS---NVPFV
A.thaliana|TAIR:gene:1006229452 SEEDKREVQDKVLGEVGKWMERFDCLVIGPGLGRDPFLLECVSIIMLLAKKS---NVPFV
D.discoideum|dictyBase:DDB0189092 ---EKNDPSDIIP-----WLLSLHVIVVGPGLGRSSGAWSCASEVIKAARNI---NLPIV
R.norvegicus|RGD:1562691 --------SSDAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKAR---DIPVV
M.musculus|MGI:1913353 --------SSNAVEEVEKWLPRLHALVVGPGLGRDDLLLNNVRGILESTKAR---DIPVV
H.sapiens|UniProtKB:Q5T9X3 --------SPNAVHEVEKWLPRLHALVVGPGLGRDDALLRNVQGILEVSKAR---DIPVV
G.gallus|RefSeq:XP_416954 --------SPNAVHEVDKWLPRLHSVVIGPGLGRDEALLENAKAIIEKSKLK---GIPII
D.melanogaster|FB:FBgn0036848 --------CVDAVERIAPWLERLHVVVIGPGLGREPGILKTASNVLKLCMDT---KKPVV
C.elegans|WP:WB:CE23917 ------------ANSIIPKLSRMDAIVIGPGLGRNPNIWPLMQELFEFVRNR---DVPFV
C.elegans|WB:WBGene00011298 ------------ANSIIPKLSRMDAIVIGPGLGRNPNIWPLMQELFEFVRNR---DVPFV
C.elegans|UniProtKB:P32740 ------------ANSIIPKLSRMDAIVIGPGLGRNPNIWPLMQELFEFVRNR---DVPFV
E.coli|P31806 ------------MDSLTESLEWADVVVIGPGLGQQEWGKKALQKVEN-------FRKPML
: . :*:*****:. : *.:
S.cerevisiae|SGD:S000001634 IDADGLFLVTQDSEVKEMLKSYPKGRVILTPNVVEFKRLCDAIG-------KKGDSHSEM
S.pombe|SPCC61.03 IDADGLWLIQQRP---ELVSGYHN--VILTPNVIEFKRLCDKLD-------IKSD-GPDA
A.thaliana|TAIR:gene:2182146 IDGDGLFLVTNSI---DLVHSYPL--AVLTPNVNEYKRLVQKVLNCE----VDEQNAEDQ
A.thaliana|TAIR:gene:1006229452 IDGDGLFLVTNSI---DLVHSYPL--AVLTPNVNEYKRLVQKVLNCE----VDEQNAEDQ
D.discoideum|dictyBase:DDB0189092 LDGDALRLICDNL---DIIKGYDK--AILTPNFVEFKSLSDSVKKMI----GDTSNNLLK
R.norvegicus|RGD:1562691 IDADGLWLIAQRP---ALVHGYQK--AVLTPNHVEFSRLWDAVLSSP----MDTSNHSGS
M.musculus|MGI:1913353 IDADGLWLVAQQP---ALIHSYHK--AILTPNHVEFSRLWEAVLSSP----MDSNDLKGS
H.sapiens|UniProtKB:Q5T9X3 IDADGLWLVAQQP---ALIHGYRK--AVLTPNHVEFSRLYDAVLRGP----MDSDDSHGS
G.gallus|RefSeq:XP_416954 IDADGLWLISQQP---SLIQGYQR--AILTPNYMEFSRLYEAMLRDP----VDSSDHHGC
D.melanogaster|FB:FBgn0036848 IDADGLFLLNDNL---NLICGQPN--VILTPNVMEFQRLF-------------GEDDQAA
C.elegans|WP:WB:CE23917 IDGDGLWFVSEHI---EKFPRQMS-ATVLTPNIVEFSRLCKSALGEEDVLNVRNNSQLQH
C.elegans|WB:WBGene00011298 IDGDGLWFVSEHI---EKFPRQMS-ATVLTPNIVEFSRLCKSALGEEDVLNVRNNSQLQH
C.elegans|UniProtKB:P32740 IDGDGLWFVSEHI---EKFPRQMS-ATVLTPNIVEFSRLCKSALGEEDVLNVRNNSQLQH
E.coli|P31806 WDADALNLLAINP------DKRHN--RVITPHPGEAARLLGCSVAEIE------SDRLHC
*.*.* :: ::**: * * .
S.cerevisiae|SGD:S000001634 GSLIAQELN-CIVVEKGQSDKIFSPDSEKDMLTNSEEGSNKRVGGQGDTLTGAISCMLAF
S.pombe|SPCC61.03 CNQLAGKLN-LLIIQKGQSD-IISDG--ATAYACSVPGGLKRCGGQGDILTGILATFLAW
A.thaliana|TAIR:gene:2182146 LRSLAKQIGGVTILRKGKSD-LISNG--ETVKSVSIYGSPRRCGGQGDILSGGVAVFLSW
A.thaliana|TAIR:gene:1006229452 LRSLAKQIGGVTILRKGKSD-LISNG--ETVKSVSIYGSPRRCGGQGDILSGGVAVFLSW
D.discoideum|dictyBase:DDB0189092 PEHIASCLGNITIVQKGKED-IITDG--NQTVVCDDEGMPRRCGGQGDILAGTVGTMYAW
R.norvegicus|RGD:1562691 VLKLSQALGNITIVQKGEQD-LISNG--QQVLVCNQEGSSRRCGGQGDLLSGSLGVMAHW
M.musculus|MGI:1913353 TLKLSQALGNITVVQKGEQD-LISNG--QQVLVCNQEGSSRRCGGQGDLLSGSLGVMVHW
H.sapiens|UniProtKB:Q5T9X3 VLRLSQALGNVTVVQKGERD-ILSNG--QQVLVCSQEGSSRRCGGQGDLLSGSLGVLVHW
G.gallus|RefSeq:XP_416954 VLRLSQALGNLTVVQKGERD-LISDG--EKVLVCSHEGSSRRCGGQGDLLSGSLGVLAHW
D.melanogaster|FB:FBgn0036848 RQKMSLLGAGVTVLEKGANDKIYLPH-CNEVHSMPSGGSGRRCGGQGDLLSGSLATFFSW
C.elegans|WP:WB:CE23917 LAAELSRKMNVTIYLKGEVDLVVTPN--GEVSKCSTESSLRRCGGQGDVTAGSLGLFLYW
C.elegans|WB:WBGene00011298 LAAELSRKMNVTIYLKGEVDLVVTPN--GEVSKCSTESSLRRCGGQGDVTAGSLGLFLYW
C.elegans|UniProtKB:P32740 LAAELSRKMNVTIYLKGEVDLVVTPN--GEVSKCSTESSLRRCGGQGDVTAGSLGLFLYW
E.coli|P31806 AKRLVQRYGGVAVLKGAGTVVAAHPD---ALGIIDAGNAGMASGGMGDVLSGIIGALLGQ
: . . ** ** :* :. :
S.cerevisiae|SGD:S000001634 SRAMYDFKICEQEEKGESSNDKPLKNWVDYAMLSCYAGCTITRECSRLGFKAKGRAMQTT
S.pombe|SPCC61.03 -RHAYLSKEWDTEGNMDAK---------ECLFLAAFGASACTRWCSRLAFKECGRATQST
A.thaliana|TAIR:gene:2182146 AQQLKSDPESPSENP---------------AILGCIAASGLLRKAASLAFTKHKRSTLTS
A.thaliana|TAIR:gene:1006229452 AQQLKSDPESPSENP---------------AILGCIAASGLLRKAASLAFTKHKRSTLTS
D.discoideum|dictyBase:DDB0189092 SQLYYKYNSNTDDKPEYPI-----------SIISAYAACSLLRHCSKKAYQISKRSTVSM
R.norvegicus|RGD:1562691 ALRAGPEKTNG-SSP---------------LLVAAWGACTLTRECNHLAFQKYGRSTTTT
M.musculus|MGI:1913353 ALRAGPEKTNG-SSP---------------LLVAAWGACTLTRECNRQAFQKYGRSTTTT
H.sapiens|UniProtKB:Q5T9X3 ALLAGPQKTNGGISD---------------LKLTIWGPEIETGVKTRAQGSCGPRTTTPT
G.gallus|RefSeq:XP_416954 AFLAGAEKTNG-QNP---------------FLVAAFGACSLTRQCNNQAFQKLGRSMTAS
D.melanogaster|FB:FBgn0036848 SLQSGEPNP---------------------ALVAACASSYFVKKLNAAAFQKFGRSLLAS
C.elegans|WP:WB:CE23917 AKKNLGDDWTSAHHE------------------AGIASSWLVRTAGRRAFEKHGRSMNTP
C.elegans|WB:WBGene00011298 AKKNLGDDWTSAHHE------------------AGIASSWLVRTAGRRAFEKHGRSMNTP
C.elegans|UniProtKB:P32740 AKKNLGDDWTSAHHE------------------AGIASSWLVRTAGRRAFEKHGRSMNTP
E.coli|P31806 KLSPYDAACAGCVAH------------------GAAADVLAARFGTRGMLATDLFSTLQR
. :
S.cerevisiae|SGD:S000001634 ----------DLNDRVGEVFAKLFG---------------------------------
S.pombe|SPCC61.03 ----------DLVRHVGKAYNALMEDEIPSVEEKIKD---------------------
A.thaliana|TAIR:gene:2182146 ----------DIIECLGESLEDICPAS-------------------------------
A.thaliana|TAIR:gene:1006229452 ----------DIIECLGESLEDICPAS-------------------------------
D.discoideum|dictyBase:DDB0189092 ----------DIINQISNGFEDLFPESSK-----------------------------
R.norvegicus|RGD:1562691 ----------DMIAEVGAAFSKLFTT--------------------------------
M.musculus|MGI:1913353 ----------DMITEVGTAFSRLFTT--------------------------------
H.sapiens|UniProtKB:Q5T9X3 SPHLLLSPSPQVQPSPGGRVWRLLSHQAVQPPSLPEARSLHHHLRHDRRGGGRLQQAL
G.gallus|RefSeq:XP_416954 ----------DMVSEVGTAFSKLFET--------------------------------
D.melanogaster|FB:FBgn0036848 ----------DMVNQIPSVFQTEFENSDPQ----------------------------
C.elegans|WP:WB:CE23917 ----------LLLDEIPKLVRDVETREMKDTVHTDSSKH-------------------
C.elegans|WB:WBGene00011298 ----------LLLDEIPKLVRDVETREMKDTVHTDSSKH-------------------
C.elegans|UniProtKB:P32740 ----------LLLDEIPKLVRDVETREMKDTVHTDSSKH-------------------
E.coli|P31806 ----------IVNPEVTDKNHDESSNSAP-----------------------------
:
| Program | Link |
|---|---|
| ClustalW alignment file | .alnp |
| ClustalW dendrogram file | .dnd |
| Notung tree file: rearranged | .jtt.rooting.0.rearrange.0 |
| Phylip amino acid sequence Maximum Likelihood method | .jtt |
| Sequences in this family (FASTA) | ORTHOMCL3076.fa |