This family has 16 members: 3 Caenorhabditis elegans, 1 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 2 Gallus gallus, 3 Homo sapiens, 2 Mus musculus, 1 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
| Notung Tree [Applet] | Organism | Protein | AmiGO |
|---|---|---|---|
 D = Duplication Event | Caenorhabditis elegans | UniProtKB:Q19300 | AmiGO |
| Caenorhabditis elegans | WB:WBGene00017349 | AmiGO | |
| Caenorhabditis elegans | WP:WB:CE04363 | ||
| Danio rerio | ZFIN:ZDB-GENE-040426-2927 (fam40a) | AmiGO | |
| Dictyostelium discoideum | dictyBase:DDB0188050 | ||
| Drosophila melanogaster | FB:FBgn0035437 | ||
| Gallus gallus | RefSeq:XP_414972 | ||
| Gallus gallus | RefSeq:XP_423542 | ||
| Homo sapiens | UniProtKB:A4D1K4 | ||
| Homo sapiens | UniProtKB:Q5VSL9 | AmiGO | |
| Homo sapiens | UniProtKB:Q9ULQ0 | ||
| Mus musculus | MGI:2443884 | AmiGO | |
| Mus musculus | MGI:2444363 | AmiGO | |
| Rattus norvegicus | RGD:1564249 | AmiGO | |
| Saccharomyces cerevisiae | SGD:S000005071 (FAR11) | AmiGO | |
| Schizosaccharomyces pombe | SPBC27B12.04c (SPBC27B12.04c) | AmiGO |
CLUSTAL W (1.83.1) multiple sequence alignment # P-POD
M.musculus|MGI:2443884 ------------------------------------------------------------
H.sapiens|UniProtKB:Q5VSL9 ------------------------------------------------------------
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 ------------------------------------------------------------
H.sapiens|UniProtKB:Q9ULQ0 ------------------------------------------------------------
H.sapiens|UniProtKB:A4D1K4 -----------MRSLQKNAENSQLPETASPSFRAMSLATWRCHPSPETKRDMGRVQEPGY
M.musculus|MGI:2444363 ------------------------------------------------------------
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 ------------------------------------------------------------
C.elegans|WP:WB:CE04363 ---------------------------------------------------------MPA
C.elegans|WB:WBGene00017349 ---------------------------------------------------------MPA
C.elegans|UniProtKB:Q19300 ---------------------------------------------------------MPA
D.discoideum|dictyBase:DDB0188050 ------------------------------------------------------------
S.pombe|SPBC27B12.04c ------------------------------------------------------------
S.cerevisiae|SGD:S000005071 MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDN
M.musculus|MGI:2443884 -----------MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPGGKAR
H.sapiens|UniProtKB:Q5VSL9 -----------MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAR
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 ---------------MDGVG-LCANNKQKQ--------------------NQMLPNKMRG
H.sapiens|UniProtKB:Q9ULQ0 ----------MEDPAAPGTGGPPANGNGNG------------------GGKGKQAAPKGR
H.sapiens|UniProtKB:A4D1K4 GGPGEPLTSSMEDPAAPGTGGPPANGNGNG------------------GGKGKQAAPKGR
M.musculus|MGI:2444363 ----------MDDPAAPGPAGSPANDNGNGN---------GNGNGNGNGGKGKPAVPKGR
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 -MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQS-------IQSRINVLNTIAASSKRIER
C.elegans|WP:WB:CE04363 HLNVKAECRIYGDKERRSADDEHVEYSESSLAAR---RSANVLKLKQLKEAQPMITPAYG
C.elegans|WB:WBGene00017349 HLNVKAECRIYGDKERRSADDEHVEYSESSLAAR---RSANVLKLKQLKEAQPMITPAYG
C.elegans|UniProtKB:Q19300 HLNVKAECRIYGDKERRSADDEHVEYSESSLAAR---RSANVLKLKQLKEAQPMITPAYG
D.discoideum|dictyBase:DDB0188050 ---------------------------------------------------------MDT
S.pombe|SPBC27B12.04c ------------------------------------------------MAATTASCISFS
S.cerevisiae|SGD:S000005071 MLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSD
M.musculus|MGI:2443884 EFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCF---EEDFR
H.sapiens|UniProtKB:Q5VSL9 EFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCF---EEDFR
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 EFTRNQRKDSEGLSEAPDLEFEYSDADKWTAELSELYSYTEGPEFLLNRKCF---EEDFH
H.sapiens|UniProtKB:Q9ULQ0 EAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENLEFTNNRRCF---EEDFK
H.sapiens|UniProtKB:A4D1K4 EAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENLEFTNNRRCF---EEDFK
M.musculus|MGI:2444363 ETFRNQRRESEGSVDCPTLEFEYGDSDGHAAELSELYSYTENLEFTTNRKCF---EEDFR
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 ASVDTDTHDADANCDGPDLDFVYADVDGYQNEIAELYSYTEFSEFQMNVKAF---EDQME
C.elegans|WP:WB:CE04363 GFIHHESSDNDGKHEQFPSTFEEFSAVQKNYVIQDLCSRMESADLEVRLKSA---RIILF
C.elegans|WB:WBGene00017349 GFIHHESSDNDGKHEQFPSTFEEFSAVQKNYVIQDLCSRMESADLEVRLKSA---RIILF
C.elegans|UniProtKB:Q19300 GFIHHESSDNDGKHEQFPSTFEEFSAVQKNYVIQDLCSRMESADLEVRLKSA---RIILF
D.discoideum|dictyBase:DDB0188050 ASISSTSSNSKSSKEQIKYTFTDFDN-DIKNEINELYSYSELSILKKSNISN---QFYHD
S.pombe|SPBC27B12.04c QFQRLKKLIDSPASKHKPMEFKGTSKDDLEDDLNSFFDCEEELFLSANKIFYSKLRVYQT
S.cerevisiae|SGD:S000005071 DGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVS---DGKHV
M.musculus|MGI:2443884 IHVSD--KKWTELDTNQHRTHAMRLLDGLEVTAR-----EKRLKVARAILYVAQGTFGEC
H.sapiens|UniProtKB:Q5VSL9 IHVTD--KKWTELDTNQHRTHAMRLLDGLEVTAR-----EKRLKVARAILYVAQGTFGEC
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 THLPD--QKWTELDSVQRRAHAMRLLDGLEVIGR-----ERRLKVARAILYMAQGTFGEC
H.sapiens|UniProtKB:Q9ULQ0 TQVQG--KEWLELEEDAQKAYIMGLLDRLEVVSR-----ERRLKVARAVLYLAQGTFGEC
H.sapiens|UniProtKB:A4D1K4 TQVQG--KEWLELEEDAQKAYIMGLLDRLEVVSR-----ERRLKVARAVLYLAQGTFGEC
M.musculus|MGI:2444363 TQVQDT-KEWLELEEDAQKTYVMGLLDRLEVVSR-----EKRLKVARAVLYLAQGTFGEC
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 LYDLP--PNWQKQDSASQRGIVMKLVDQLEVSDR-----SFRMQAARCILYLAQGCWAEV
C.elegans|WP:WB:CE04363 LLQGSA-TDFGCLENEEIEYQYDQKLLMNVPIRK-----TKEMDPEGPSMVYHRAIENSF
C.elegans|WB:WBGene00017349 LLQGSA-TDFGCLENEEIEYQYDQKLLMNVPIRK-----TKEMDPEGPSMVYHRAIENSF
C.elegans|UniProtKB:Q19300 LLQGSA-TDFGCLENEEIEYQYDQKLLMNVPIRK-----TKEMDPEGPSMVYHRAIENSF
D.discoideum|dictyBase:DDB0188050 LHEYTSKNKWRDLTDIEKIDYLQHLIGFFELSMKGQDNYNRYLLKSRFIWYIAQGVRDET
S.pombe|SPBC27B12.04c VRHWSLKQNWSSMSLDQKRNFILHCHHELSSGEL------LRNSALYSILYIAAGAYDSV
S.cerevisiae|SGD:S000005071 PINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEW
M.musculus|MGI:2443884 SSEAEVQFWMRYNIFLLLEVGTFNALV----------ELLNMEIDNSAA-CSSAVRKPAI
H.sapiens|UniProtKB:Q5VSL9 SSEAEVQSWMRYNIFLLLEVGTFNALV----------ELLNMEIDNSAA-CSSAVRKPAI
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 SSELEVQHWMRYNVFLLLDVGAFTALV----------ELLNMEIDNSAA-CSSAVRKPAI
H.sapiens|UniProtKB:Q9ULQ0 DSEVDVLHWSRYNCFLLYQMGTFSTFL----------ELLHMEIDNSQA-CSSALRKPAV
H.sapiens|UniProtKB:A4D1K4 DSEVDVLHWSRYNCFLLYQMGTFSTFL----------ELLHMEIDNSQA-CSSALRKPAV
M.musculus|MGI:2444363 DSEVDVLHWSRYNCFLLYQMGTFSAFL----------ELLHMEIDNSQA-SSSALRKPAV
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 QSDEEQHQITRDNVLVLYQLGVFASFI----------DLLNMEIESACSPDIVAVKITNV
C.elegans|WP:WB:CE04363 ICYKNGVYQALCTLLMTEIKEPFESPP----------NDGRISKASSRSSRNASLADLSD
C.elegans|WB:WBGene00017349 ICYKNGVYQALCTLLMTEIKEPFESPP----------NDGRISKASSRSSRNASLADLSD
C.elegans|UniProtKB:Q19300 ICYKNGVYQALCTLLMTEIKEPFESPP----------NDGRISKASSRSSRNASLADLSD
D.discoideum|dictyBase:DDB0188050 HDRKDQLHQSKLNCILLREINALPIIL----------KTLVLSSQISNETLRNQQQQQQQ
S.pombe|SPBC27B12.04c GSFEEHVHSISENVYLLREFDIPKTVY----------SLFIEWNRTRKHSFLDNSR----
S.cerevisiae|SGD:S000005071 FCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASNLLALSYISM
M.musculus|MGI:2443884 S----------LADSTDLRVLLNIMYLIVETVHQDC---DGDKAEWRTMRQTFRAELGSP
H.sapiens|UniProtKB:Q5VSL9 S----------LADSTDLRVLLNIMYLIVETVHQEC---EGDKAEWRTMRQTFRAELGSP
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 S----------LADSTDLRVLLNIMYLMVETIQREE---PTDSPEWRTIRETFKSELGSP
H.sapiens|UniProtKB:Q9ULQ0 S----------IADSTELRVLLSVMYLMVENIRLER---ETDPCGWRTARETFRTELSFS
H.sapiens|UniProtKB:A4D1K4 S----------IADSTELRVLLSVMYLMVENIRLER---ETDPCGWRTARETFRTELSFS
M.musculus|MGI:2444363 S----------IADSTELRVLLSVMYLMVENIRLER---EIDPCGWRTARETFRTELSFS
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 T----------LVDSTDIRVILSVLYIITETIRDEK---EKGSEDYRELADSFVQEINSP
C.elegans|WP:WB:CE04363 SEKWRTRQLPTMVDNEMLRVILAGLYHMIVQILDERSGREDETDSDLETRKAFREEVQEP
C.elegans|WB:WBGene00017349 SEKWRTRQLPTMVDNEMLRVILAGLYHMIVQILDERSGREDETDSDLETRKAFREEVQEP
C.elegans|UniProtKB:Q19300 SEKWRTRQLPTMVDNEMLRVILAGLYHMIVQILDERSGREDETDSDLETRKAFREEVQEP
D.discoideum|dictyBase:DDB0188050 QQQQQQQQQQQQQQQNENEGSGEGGTNFTTTTTTTTTTTTANTFISHGKRNNIIKNNSGS
S.pombe|SPBC27B12.04c -------------DEGFLNLLLSLMFFFLTLNNTDKTWIHSIRSLNPPVLPTLVKLFIDI
S.cerevisiae|SGD:S000005071 GCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSST
M.musculus|MGI:2443884 LYNN-EPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTL
H.sapiens|UniProtKB:Q5VSL9 LYNN-EPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSI
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 LYNH-EPVSVMLFGMVTKFCSGHAPHFPMKKVLLLLWKTILFTLGGFEQLQSCKISRRAA
H.sapiens|UniProtKB:Q9ULQ0 MHNE-EPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAE
H.sapiens|UniProtKB:A4D1K4 MHNE-EPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAE
M.musculus|MGI:2444363 THNE-EPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAE
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 LPDG-ELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLK
C.elegans|WP:WB:CE04363 IENGNEPLLIVLFDMLHPFYIGTAPHFPIKKIVLLIWKILLLTLGGWEELTVRKREKRMT
C.elegans|WB:WBGene00017349 IENGNEPLLIVLFDMLHPFYIGTAPHFPIKKIVLLIWKILLLTLGGWEELTVRKREKRMT
C.elegans|UniProtKB:Q19300 IENGNEPLLIVLFDMLHPFYIGTAPHFPIKKIVLLIWKILLLTLGGWEELTVRKREKRMT
D.discoideum|dictyBase:DDB0188050 VSGVIKNINSNGTLSSSMKVNVKRADLLMSILLDIIYLIIINNKD--DELFKEEIFESLE
S.pombe|SPBC27B12.04c TSDYQLNLDKVIHSSLKKLS------FLIFKVCIRLWGSQSYLQEKKAGLAEVLNISTSQ
S.cerevisiae|SGD:S000005071 ILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMRIRNMISLL
M.musculus|MGI:2443884 LGLPPLPEDSIKVIRNMRAASPPAS----ASDLIE-----QQQK------RGRR--EHKA
H.sapiens|UniProtKB:Q5VSL9 LGLPPLPEDSIKVIRNMRAASPPAS----ASDLIE-----QQQK------RGRR--EHKA
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 LGLPPLPEDSIRVVRSMRAASPPAS----ASDLIE-----QQQR------RARR--EHKA
H.sapiens|UniProtKB:Q9ULQ0 LGLPPLAEDSIQVVKSMRAASPPSY----TLDLGE-----SQLAPPPSKLRGRRGSRRQL
H.sapiens|UniProtKB:A4D1K4 LGLPPLAEDSIQVVKSMRAASPPSY----TLDLGE-----SQLAPPPSKLRGRRGSRRQL
M.musculus|MGI:2444363 LGLPPLAEDSIQVVKSMRAASPPSY----TLDLGE-----SQLAPPPSKLRGRRGSRRQL
G.gallus|RefSeq:XP_414972 ------------------------------MEFNN-----SMWSPAPQ------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 VGLEPITEDTLEVTKCMRASSPPAT----ATDILENQYPKRNFKRSLMKQRFLDEPEQID
C.elegans|WP:WB:CE04363 AGLD-IMEDTITVAASQ--AAFIAK----DQEHVR-----NMAHRAGSFARGGMMARQMA
C.elegans|WB:WBGene00017349 AGLD-IMEDTITVAASQ--AAFIAK----DQEHVR-----NMAHRAGSFARGGMMARQMA
C.elegans|UniProtKB:Q19300 AGLD-IMEDTITVAASQ--AAFIAK----DQEHVR-----NMAHRAGSFARGGMMARQMA
D.discoideum|dictyBase:DDB0188050 GCNNNNNNNNNYNNNILGKNNNNGT----NCDNPNLISIILQLLSEFNEIDGNLYPIKKI
S.pombe|SPBC27B12.04c QKPKTTALDYEVFRHEMATKFSSFA----DSYYPVP-------------LDREQAHILPT
S.cerevisiae|SGD:S000005071 FKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKHPEKLSISPLHYQAFREDITSRFPDYNM
M.musculus|MGI:2443884 LIKQDNLDAFNERDPYKADD--SREEEEENDD-DSSLEGEAFPLERDEVMPPPLQHPQ--
H.sapiens|UniProtKB:Q5VSL9 LIKQDNLDAFNERDPYKADD--SREEEEENDD-DNSLEGETFPLERDEVMPPPLQHPQ--
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 LIKQDNLDTFNEKDPYKADD--SHEDEEENDDNDNSLEAEPFPLERDEVMPPPIPHPP--
H.sapiens|UniProtKB:Q9ULQ0 LTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLS
H.sapiens|UniProtKB:A4D1K4 LTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLS
M.musculus|MGI:2444363 LTKQDSLDIYNERDLFKTEEPATEEEEESAADGERTLDGELDLLEQDPLVPPPPSQTPLS
G.gallus|RefSeq:XP_414972 ------------------------------------------------------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 MEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAA
C.elegans|WP:WB:CE04363 YNDDSKDEDAYSEASSEDSTIASKKEDSPGASSSTPPSIPDTASNFRQGSGEQTPRVGSP
C.elegans|WB:WBGene00017349 YNDDSKDEDAYSEASSEDSTIASKKEDSPGASSSTPPSIPDTASNFRQGSGEQTPRVGSP
C.elegans|UniProtKB:Q19300 YNDDSKDEDAYSEASSEDSTIASKKEDSPGASSSTPPSIPDTASNFRQGSGEQTPRVGSP
D.discoideum|dictyBase:DDB0188050 LMVLWKSLTIFMGGLEDLDRLKQERLDNVGYKKGTPKTRSYDISNFIKSTQRYHSQLKSN
S.pombe|SPBC27B12.04c LNTDSFHKSSFISSTRLCSPENPSLLVNTAKTSKMSARREQFQTNQNLPFCFTPNLEKLT
S.cerevisiae|SGD:S000005071 PSSGLPKDVDKSESLSQFLEIPRPKSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEG
M.musculus|MGI:2443884 TDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLG-SDTNTVVGLPRPIHESIKTLK
H.sapiens|UniProtKB:Q5VSL9 TDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLG-SDTNTVVGLPRPIHESIKTLK
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 TERMCFPKGLPWAPKVREKDIESFLESSRSKFIGYTLG-NDTDTVVGLPRPIHESIKTLK
H.sapiens|UniProtKB:Q9ULQ0 AERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLG-QDTDTLVGLPRPIHESVKTLK
H.sapiens|UniProtKB:A4D1K4 AERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLG-QDTDTLVGLPRPIHESVKTLK
M.musculus|MGI:2444363 TDRVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLG-QDTDTLVGLPRPIHESVKTLK
G.gallus|RefSeq:XP_414972 ----------------QQKDIEHFLEASRNKFIGFTLG-QDTETLIGLPRPIHESVKTLK
G.gallus|RefSeq:XP_423542 ----------------------------------------------------------MT
D.melanogaster|FB:FBgn0035437 VPPVQITARLPWTPKVRQKDIDQFLDISRNKFIGYSLI-GDHESLAGLPQPIHEGFKTLQ
C.elegans|WP:WB:CE04363 VFPVIQKKTLPWRSKTNAQDIEDFIQKGRFKYFNYDFDPGDDTTLFGLPPSFCGAVKILR
C.elegans|WB:WBGene00017349 VFPVIQKKTLPWRSKTNAQDIEDFIQKGRFKYFNYDFDPGDDTTLFGLPPSFCGAVKILR
C.elegans|UniProtKB:Q19300 VFPVIQKKTLPWRSKTNAQDIEDFIQKGRFKYFNYDFDPGDDTTLFGLPPSFCGAVKILR
D.discoideum|dictyBase:DDB0188050 SVLHKVNTHYLGTPKEYKDVDVFRLPLSLSDSLSVLQTNLYPPEKVRKEIGINYYSFNNN
S.pombe|SPBC27B12.04c IPYSVTEAANVFQNKTKRTLAVEQLLSERELLRRFTLQQRLVADLHEFYNSVKGPAHSFE
S.cerevisiae|SGD:S000005071 PRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIE-RKPDNDIVIPFSTEEAARILS
M.musculus|MGI:2443884 -QHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPA--ETLYQGLLPSLPQ--YMIALLK
H.sapiens|UniProtKB:Q5VSL9 -QHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPA--ETLYQGLLPSLPQ--YMIALLK
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 -QHKYVSIAEVQIAKEEAFQKTPLSGGEEELELCAT--ELLYQGILPSLPQ--YMIALLK
H.sapiens|UniProtKB:Q9ULQ0 -QHKYISIADVQIKNEEELEKCPMSLGEEVVPETPC--EILYQGMLYSLPQ--YMIALLK
H.sapiens|UniProtKB:A4D1K4 -QHKYISIADVQIKNEEELEKCPMSLGEEVVPETPC--EILYQGMLYSLPQ--YMIALLK
M.musculus|MGI:2444363 -QHKYISIADIQIKNEEELEKCPLSLGEEVVPETPS--EILYQGMLYSLPQ--YMIALLK
G.gallus|RefSeq:XP_414972 -QHKYISISDVQIKNEEELEKCPMSLGEEEVQETPC--EVLYRAILYNLPQ--YMIALLK
G.gallus|RefSeq:XP_423542 -TFGLVACWEVCAAAG---------------TDCRC--LLVAQGMAG-------------
D.melanogaster|FB:FBgn0035437 -RHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPA--EVLYQAILPNLPQ--YMIALLK
C.elegans|WP:WB:CE04363 -NNMYTSLTELQVKKDEELNRYLFSMKED-IPETKT--ETLYRKILPNLSQ--YICALVK
C.elegans|WB:WBGene00017349 -NNMYTSLTELQVKKDEELNRYLFSMKED-IPETKT--ETLYRKILPNLSQ--YICALVK
C.elegans|UniProtKB:Q19300 -NNMYTSLTELQVKKDEELNRYLFSMKED-IPETKT--ETLYRKILPNLSQ--YICALVK
D.discoideum|dictyBase:DDB0188050 -DTITPHTQSDYFYNTSNISSSKKQIKPRILIDNPSNFERFYCMNVSNFSK--IVIILLK
S.pombe|SPBC27B12.04c TEDPVLKFVSQSYDDLFPYMDNFIQLAVQLFYHISKKVNCLYVEAFSSSDA--VLQRIQD
S.cerevisiae|SGD:S000005071 -ESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQR
M.musculus|MGI:2443884 ILLAAAPTSKAKTDSINILADVLPEEMP-TTVLQS---------------MKLGVDVNRH
H.sapiens|UniProtKB:Q5VSL9 ILLAAAPTSKAKTDSINILADVLPEEMP-TTVLQS---------------MKLGVDVNRH
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 ILLAAAPTSKAKTDSINILADVLPEEMP-TTVLQS---------------MKLGVDVNRH
H.sapiens|UniProtKB:Q9ULQ0 ILLAAAPTSKAKTDSINILADVLPEEMP-ITVLQS---------------MKLGIDVNRH
H.sapiens|UniProtKB:A4D1K4 ILLAAAPTSKAKTDSINILADVLPEEMP-ITVLQS---------------MKLGIDVNRH
M.musculus|MGI:2444363 ILLAAAPTSKAKTDSINILADVLPEEMP-VTVLQS---------------MKLGIDVNRH
G.gallus|RefSeq:XP_414972 ILLAAAPTSKAKTDSINILADVLPEEMP-ITVLQS---------------MKLGIDVNRH
G.gallus|RefSeq:XP_423542 --MPSDPSRGGSGRVQALRRAKHPSVCPRTTVLQS---------------MKLGVDVNRH
D.melanogaster|FB:FBgn0035437 VLLAASPTSKSKTESINIMADVLPRKMP-LTATQS---------------TKLTVDIGRH
C.elegans|WP:WB:CE04363 VMVSSVPSTKARHEGLNVLIDCLTPEMEASDILSNSISLDNSTSSPLEEGFRLAIDINRH
C.elegans|WB:WBGene00017349 VMVSSVPSTKARHEGLNVLIDCLTPEMEASDILSNSISLDNSTSSPLEEGFRLAIDINRH
C.elegans|UniProtKB:Q19300 VMVSSVPSTKARHEGLNVLIDCLTPEMEASDILSNSISLDNSTSSPLEEGFRLAIDINRH
D.discoideum|dictyBase:DDB0188050 ILLAATPVVKNYTGPINLIAEIVIDQSSPGSSASLVET------------MQSAIDFLRH
S.pombe|SPBC27B12.04c NAVVDSPTEELSEQAARNRKSNVKIEYTEDFATGFAISG------------EISHSIN-N
S.cerevisiae|SGD:S000005071 IDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLN-----MLTPQLEIVRA
M.musculus|MGI:2443884 KEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQN-------IMS
H.sapiens|UniProtKB:Q5VSL9 KEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQN-------IMS
R.norvegicus|RGD:1564249 ------------------------------------------------------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 KEIIVKAISAILLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQN-------IMS
H.sapiens|UniProtKB:Q9ULQ0 KEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQN-------ILS
H.sapiens|UniProtKB:A4D1K4 KEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQN-------ILS
M.musculus|MGI:2444363 KEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQN-------ILS
G.gallus|RefSeq:XP_414972 KEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQN-------IMS
G.gallus|RefSeq:XP_423542 KEIIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQN-------IMS
D.melanogaster|FB:FBgn0035437 KEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQT-------ITE
C.elegans|WP:WB:CE04363 KEIIVKSLSAILLLLVKHFKLNHIYQFEYICQQIVYVNGIPLILKFLDQN-------TNK
C.elegans|WB:WBGene00017349 KEIIVKSLSAILLLLVKHFKLNHIYQFEYICQQIVYVNGIPLILKFLDQN-------TNK
C.elegans|UniProtKB:Q19300 KEIIVKSLSAILLLLVKHFKLNHIYQFEYICQQIVYVNGIPLILKFLDQN-------TNK
D.discoideum|dictyBase:DDB0188050 KEIISKSTLGILLLIIKHSKFNQHLQFEYLSKIMYESNALVLLYKCLNHESVEKYLFSQN
S.pombe|SPBC27B12.04c LEFVLYSLSSLFLMMLKWFRLSHVLRFERLAFLLYENHFLEIFNRHLTEG-----DCNRN
S.cerevisiae|SGD:S000005071 KELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSKYS---EVYPER
M.musculus|MGI:2443884 YITAKNSISVLDYPHCVVN------ELPELTA-----ESLEAG-------------DNNQ
H.sapiens|UniProtKB:Q5VSL9 YITAKNSISVLDYPHCVVH------ELPELTA-----ESLEAG-------------DSNQ
R.norvegicus|RGD:1564249 --------------------------------------------------------DNNQ
D.rerio|ZFIN:ZDB-GENE-040426-2927 YITAKNSISALDFPHCVIH------ELPELTA-----ESLEAG-------------DNNQ
H.sapiens|UniProtKB:Q9ULQ0 YITAKNSISVLDYPCCTIQ------DLPELTT-----ESLEAG-------------DNSQ
H.sapiens|UniProtKB:A4D1K4 YITAKNSISVLDYPCCTIQ------DLPELTT-----ESLEAG-------------DNSQ
M.musculus|MGI:2444363 YITAKNSISVLDYPCCTIQ------DLPELTT-----ESLEAG-------------DNSQ
G.gallus|RefSeq:XP_414972 YITAKNSISVLDYPHCTVH------DLPELTA-----ESLEAG-------------DNNQ
G.gallus|RefSeq:XP_423542 YITAKNSISVLDYPYCVVL------ELPELTA-----ESLVY---------------NNQ
D.melanogaster|FB:FBgn0035437 YVNTKNSIPLLDFPSCVIG------EQPDLSG-----DSFVYGGE---------M-SDKS
C.elegans|WP:WB:CE04363 LIQSRHEIYAYNYPQCLYHYVRNNEEWPILTQ-----DNIEEPRP---------PGAGPY
C.elegans|WB:WBGene00017349 LIQSRHEIYAYNYPQCLYHYVRNNEEWPILTQ-----DNIEEPRP---------PGAGPY
C.elegans|UniProtKB:Q19300 LIQSRHEIYAYNYPQCLYHYVRNNEEWPILTQ-----DNIEEPRP---------PGAGPY
D.discoideum|dictyBase:DDB0188050 YLNSEEYFNEESLPSSSAASPPPPPIFQPLNCSGSSINSISSGGAGCEGGGANPPPVQLF
S.pombe|SPBC27B12.04c TEKDVKCVRGGFFSYSSKMYKYDRVSIPVITR---------------------------A
S.cerevisiae|SGD:S000005071 VFNKYVQTPNSFWKECSLSNESYRESYSVDDS--------------------------GE
M.musculus|MGI:2443884 FCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKV
H.sapiens|UniProtKB:Q5VSL9 FCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKV
R.norvegicus|RGD:1564249 FCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKV
D.rerio|ZFIN:ZDB-GENE-040426-2927 FCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKV
H.sapiens|UniProtKB:Q9ULQ0 FCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKL
H.sapiens|UniProtKB:A4D1K4 FCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKL
M.musculus|MGI:2444363 FCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKI
G.gallus|RefSeq:XP_414972 FCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKI
G.gallus|RefSeq:XP_423542 FCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKV
D.melanogaster|FB:FBgn0035437 YSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKM
C.elegans|WP:WB:CE04363 FMWRNVFFAINLIRLLNKLVKAKNDRVKMLMVFKSAPVLKRLFKVRVSVLQLYVLKAIKM
C.elegans|WB:WBGene00017349 FMWRNVFFAINLIRLLNKLVKAKNDRVKMLMVFKSAPVLKRLFKVRVSVLQLYVLKAIKM
C.elegans|UniProtKB:Q19300 FMWRNVFFAINLIRLLNKLVKAKNDRVKMLMVFKSAPVLKRLFKVRVSVLQLYVLKAIKM
D.discoideum|dictyBase:DDB0188050 ENYKNLFSTITSLKLIQKVMKHHPSRISSLSASKSANILKKYCSINHPMIRLYSLKVIKN
S.pombe|SPBC27B12.04c SSSRNLLITMNCLRVLEKVCKYSNIRKEIIARSNLHENLKKLLAIPHDKLRLYALKVLKL
S.cerevisiae|SGD:S000005071 VDTEIMPSFAYLLRILRKVTGNKTQRLKELPLS-IGILFKRYYRLFNLDMYHPILKITRE
. : ::::.*: * : :*: : : ** :
M.musculus|MGI:2443884 QTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFN
H.sapiens|UniProtKB:Q5VSL9 QTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFN
R.norvegicus|RGD:1564249 QTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFN
D.rerio|ZFIN:ZDB-GENE-040426-2927 QTKYLGRQWRKGNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFN
H.sapiens|UniProtKB:Q9ULQ0 QTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFN
H.sapiens|UniProtKB:A4D1K4 QTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFN
M.musculus|MGI:2444363 QTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFN
G.gallus|RefSeq:XP_414972 QTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRASIEAFN
G.gallus|RefSeq:XP_423542 QTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGN------------------------
D.melanogaster|FB:FBgn0035437 QTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFN
C.elegans|WP:WB:CE04363 QSRYLGRQWRKSNMDIISAIYSRVRHRMTDDWAFASDIK-RKCDYQKEDSLIKASIERFH
C.elegans|WB:WBGene00017349 QSRYLGRQWRKSNMDIISAIYSRVRHRMTDDWAFASDIK-RKCDYQKEDSLIKASIERFH
C.elegans|UniProtKB:Q19300 QSRYLGRQWRKSNMDIISAIYSRVRHRMTDDWAFASDIK-RKCDYQKEDSLIKASIERFH
D.discoideum|dictyBase:DDB0188050 LVPYQTKKWKQINMRIISDIYLEVPIHINDNWLFSHNSAINNNNNNSNNNNNNNNNNSTN
S.pombe|SPBC27B12.04c SVPFLGLKWKQANMSIITQIYLNCSLDLRDSWMFHENGSDTYRSAQLQETFLAILIRFYH
S.cerevisiae|SGD:S000005071 LTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYN
: :*:. :* :: :* : *.*
M.musculus|MGI:2443884 ARRY----------------DRTHS-----NPDFLPVDNCLQS-----------------
H.sapiens|UniProtKB:Q5VSL9 ARRY----------------DRAHS-----NPDFLPVDNCLQS-----------------
R.norvegicus|RGD:1564249 ARRY----------------DRTHS-----NPDFLPVDNCLQS-----------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 SRRY----------------DKNQS-----NPEFLPVDNCLQS-----------------
H.sapiens|UniProtKB:Q9ULQ0 SRRY----------------DRPQ------DSEFSPVDNCLQS-----------------
H.sapiens|UniProtKB:A4D1K4 SRRY----------------DRPQ------DSEFSPVDNCLQS-----------------
M.musculus|MGI:2444363 SRRY----------------DKPQ------DSEFSPVDNCLQS-----------------
G.gallus|RefSeq:XP_414972 SRRY----------------DKPQ------DSEFAPVDNCLQS-----------------
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 LRRY----------------PEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANG
C.elegans|WP:WB:CE04363 SRRYSALYPQFAIEVNDAPMPGDDYLNRVDMRDFEPVDTCAHS-----------------
C.elegans|WB:WBGene00017349 SRRYSALYPQFAIEVNDAPMPGDDYLNRVDMRDFEPVDTCAHS-----------------
C.elegans|UniProtKB:Q19300 SRRYSALYPQFAIEVNDAPMPGDDYLNRVDMRDFEPVDTCAHS-----------------
D.discoideum|dictyBase:DDB0188050 NDNGLTDEHEVTLQEKVEEYHRVNYEQWYTNDGLDMCYKNDHSMGIG-------------
S.pombe|SPBC27B12.04c IRLYG----------------------KKCKSLYQFCILEEMR-----------------
S.cerevisiae|SGD:S000005071 FQHY--------------------------------------------------------
M.musculus|MGI:2443884 ----------------------VLG-----------------------QRVDLPEDFQMN
H.sapiens|UniProtKB:Q5VSL9 ----------------------VLG-----------------------QRVDLPEDFQMN
R.norvegicus|RGD:1564249 ----------------------VLG-----------------------QRVDLPEDFQMN
D.rerio|ZFIN:ZDB-GENE-040426-2927 ----------------------VLG-----------------------QRIDLPEDFQMN
H.sapiens|UniProtKB:Q9ULQ0 ----------------------VLG-----------------------QRLDLPEDFHYS
H.sapiens|UniProtKB:A4D1K4 ----------------------VLG-----------------------QRLDLPEDFHYS
M.musculus|MGI:2444363 ----------------------VLG-----------------------QRLDLPEDFHYS
G.gallus|RefSeq:XP_414972 ----------------------VLG-----------------------QRLELPEDFHYS
G.gallus|RefSeq:XP_423542 ------------------------------------------------------------
D.melanogaster|FB:FBgn0035437 YGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKAN
C.elegans|WP:WB:CE04363 ----------------------VLG-----------------------ANLKLGRHFKKD
C.elegans|WB:WBGene00017349 ----------------------VLG-----------------------ANLKLGRHFKKD
C.elegans|UniProtKB:Q19300 ----------------------VLG-----------------------ANLKLGRHFKKD
D.discoideum|dictyBase:DDB0188050 ------------------IFDDLLN--------------------SLQLTTEEKQAIEND
S.pombe|SPBC27B12.04c ------------------------------------------------LKKSIEELAASN
S.cerevisiae|SGD:S000005071 --------------------------------------------------EISMEDLGYG
M.musculus|MGI:2443884 YDLWLEREVFSKPISWEELLQ---------------
H.sapiens|UniProtKB:Q5VSL9 YDLWLEREVFSKPISWEELLQ---------------
R.norvegicus|RGD:1564249 YDLWLEREVFSKPISWEELLQ---------------
D.rerio|ZFIN:ZDB-GENE-040426-2927 YDLWLEREVFSKPISWEELLQ---------------
H.sapiens|UniProtKB:Q9ULQ0 YELWLEREVFSQPICWEELLQNH-------------
H.sapiens|UniProtKB:A4D1K4 YELWLEREVFSQPICWEELLQNH-------------
M.musculus|MGI:2444363 YELWLEREVFSQPICWEELLQNH-------------
G.gallus|RefSeq:XP_414972 YELWLEREVFSQPIRWEELLRYQ-------------
G.gallus|RefSeq:XP_423542 ------------------------------------
D.melanogaster|FB:FBgn0035437 YAVWLEEEVYNSQTDWDAL-----------------
C.elegans|WP:WB:CE04363 YEKWLEQEVFNASIDWDKLLIETRGVEDLM------
C.elegans|WB:WBGene00017349 YEKWLEQEVFNASIDWDKLLIETRGVEDLM------
C.elegans|UniProtKB:Q19300 YEKWLEQEVFNASIDWDKLLIETRGVEDLM------
D.discoideum|dictyBase:DDB0188050 RLAYIDKDEGSSLIFMNDALEDELLFNKWNIQKPKF
S.pombe|SPBC27B12.04c MMEYIPESLWSYSFERSDTGFFENEFAAMHINDIA-
S.cerevisiae|SGD:S000005071 HRNSSSQDLLNKESEYLNI-----------------
| Program | Link |
|---|---|
| ClustalW alignment file | .alnp |
| ClustalW dendrogram file | .dnd |
| Notung tree file: rearranged | .jtt.rooting.0.rearrange.0 |
| Phylip amino acid sequence Maximum Likelihood method | .jtt |
| Sequences in this family (FASTA) | ORTHOMCL2187.fa |