This family has 22 members: 1 Arabidopsis thaliana, 5 Caenorhabditis elegans, 3 Danio rerio, 1 Dictyostelium discoideum, 1 Drosophila melanogaster, 1 Escherichia coli, 2 Gallus gallus, 2 Homo sapiens, 2 Mus musculus, 2 Rattus norvegicus, 1 Saccharomyces cerevisiae, 1 Schizosaccharomyces pombe.
| Protein | Publication | Curator Notes |
|---|
| SGD:S000005164 | ![[PubMed]](http://yfgdb.princeton.edu/PubMed.gif) 8706758: Gallert KC, et al. Enzymatic properties and inhibition by single-stranded autonomously replicating sequences of adenylosuccinate synthase from Saccharomyces cerevisiae. Eur J Biochem. 1996 Jul 15;239(2):487-93. | The S. cerevisiae protein ADE12 complements the orthologous mutation in E. coli. |
CLUSTAL W (1.83.1) multiple sequence alignment # P-POD
D.discoideum|dictyBase:DDB0201565 ------------------------------------------------------------
A.thaliana|TAIR:gene:2076605 MSLSSLTLDSNPRFAVGGPYHRRYPPLHHPRSFVSCSAKRPAVSASLSVAADSAATESLG
S.cerevisiae|SGD:S000005164 ------------------------------------------------------------
S.pombe|SPAC144.03 -------------MASVRETG---------------------------------------
R.norvegicus|RGD:1310508 -----------MSISESSPAATSLP----------NGDCGRPR-----------------
M.musculus|MGI:87948 -----------MSISESSPAATSLP----------NGDCGRPR-----------------
H.sapiens|UniProtKB:P30520 -----------MAFAETYPAASSLP----------NGDCGRPR-----------------
G.gallus|UniProtKB:Q5ZJL5 -------------MAEHGAPAPAIP----------NGGCA--------------------
D.rerio|ZFIN:ZDB-GENE-050417-337 -------------MSDSGDAQPQDGG---------NSSSSRGK-----------------
R.norvegicus|RGD:1590342 -------------MSGTRASNDRPP---------GTGGVKRGR-------------LQQE
M.musculus|MGI:87947 -------------MSGTRASNDRPP---------GTGGVKRGR-------------LQQE
H.sapiens|UniProtKB:Q8N142 -------------MSGTRASNDRPP---------GAGGVKRGR-------------LQQE
G.gallus|RefSeq:XP_001235680 -------------MRAEAGDNLKKLLEVEKRLFLSTEDLKIQHTEFVQNSVSASKDLQEE
D.rerio|ZFIN:ZDB-GENE-040516-18 -------------MSSGWSQNDHRS---------YSNPPPVSG--------------KRP
D.rerio|ZFIN:ZDB-GENE-020419-28 -------------MSNGQETACLNG----------EPALKRSRD---------SLDSLRV
D.melanogaster|FB:FBgn0027493 -------------MSASATNGTHYE------------QLHQGR-----------------
C.elegans|WP:WB:CE08630 -------------MGSVTSKTNDELES--------FLNKRLGG----------------S
C.elegans|WB:WBGene00016509 -------------MGSVTSKTNDELES--------FLNKRLGG----------------S
C.elegans|UniProtKB:Q8MNS2 -------------MGSVTSKTNDELES--------FLNKRLGG----------------S
C.elegans|WP:WB:CE29709 ------------------------------------------------------------
C.elegans|UniProtKB:P91134 ------------------------------------------------------------
E.coli|P0A7D4 ------------------------------------------------------------
D.discoideum|dictyBase:DDB0201565 ------MASIIIGSQWGDEGKGKLVDILSQQFDV----VARCQGGANAGHTIVVD-GKKI
A.thaliana|TAIR:gene:2076605 RIGSLSQVSGVLGCQWGDEGKGKLVDILAQHFDI----VARCQGGANAGHTIYNSEGKKF
S.cerevisiae|SGD:S000005164 ------MVNVVLGSQWGDEGKGKLVDLLVGKYDI----VARCAGGNNAGHTIVVD-GVKY
S.pombe|SPAC144.03 VNVSNDGITVVLGSQWGDEGKGKLVDILCDNVDV----CARCQGGNNAGHTIVAN-GVTY
R.norvegicus|RGD:1310508 ARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADI----VCRCQGGNNAGHTVVVD-SVEY
M.musculus|MGI:87948 ARSGGNRVTVVLGAQWGDEGKGKVVDLLAQDADI----VCRCQGGNNAGHTVVVD-SVEY
H.sapiens|UniProtKB:P30520 ARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADI----VCRCQGGNNAGHTVVVD-SVEY
G.gallus|UniProtKB:Q5ZJL5 ARLPGNKVTVVLGAQWGDEGKGKVVDLLAQDADI----VCRCQGGNNAGHTVVVD-SVEY
D.rerio|ZFIN:ZDB-GENE-050417-337 SPSVGNRVTVVLGAQWGDEGKGKVVDLLAQDADM----VCRCQGGNNAGHTVVVD-SVEY
R.norvegicus|RGD:1590342 AAATGSRVTVVLGAQWGDEGKGKVVDLLATDADI----VSRCQGGNNAGHTVVVD-GKEY
M.musculus|MGI:87947 AAATGSRVTVVLGAQWGDEGKGKVVDLLATDADI----VSRCQGGNNAGHTVVVD-GKEY
H.sapiens|UniProtKB:Q8N142 AAATGSRVTVVLGAQWGDEGKGKVVDLLATDADI----ISRCQGGNNAGHTVVVD-GKEY
G.gallus|RefSeq:XP_001235680 LANIEKKKEELADYLCEDRKKMSLEDVFNTMKTFRELFLKALQGGNNAGHTVVVD-GKEY
D.rerio|ZFIN:ZDB-GENE-040516-18 RNDSGNKVTVVLGAQWGDEGKGKVVDLLATESDI----VGRCQGGNNAGHTVVVE-EKEY
D.rerio|ZFIN:ZDB-GENE-020419-28 PREPQNKVTVVLGAQWGDEGKGKVVDLLAMDADI----VCRCQGGNSAGHTVVVD-SVEY
D.melanogaster|FB:FBgn0027493 TKMYKSKVDVVLGAQWGDEGKGKVVDMLASDVDI----VCRCQGGNNAGHTVVAN-GTEF
C.elegans|WP:WB:CE08630 MTSSNKTVSVLLGAQWGDEGKGKIIDYLIENHKIN--VTARCQGGNNAGHTVVAN-GRKY
C.elegans|WB:WBGene00016509 MTSSNKTVSVLLGAQWGDEGKGKIIDYLIENHKIN--VTARCQGGNNAGHTVVAN-GRKY
C.elegans|UniProtKB:Q8MNS2 MTSSNKTVSVLLGAQWGDEGKGKIIDYLIENHKIN--VTARCQGGNNAGHTVVAN-GRKY
C.elegans|WP:WB:CE29709 MTSSNKTVSVLLGAQWGDEGKGKIIDYLIENHKIN--VTARCQGGNNAGHTVVAN-GRKY
C.elegans|UniProtKB:P91134 MTSSNKTVSVLLGAQWGDEGKGKIIDYLIENHKIN--VTARCQGGNNAGHTVVAN-GRKY
E.coli|P0A7D4 ----MGNNVVVLGTQWGDEGKGKIVDLLTERAKY----VVRYQGGHNAGHTLVIN-GEKT
: . *. * .: * : ** .****: .
D.discoideum|dictyBase:DDB0201565 ALHLIPSGILNEKASCILGNGMVIHLPTFFKEVQGLQDKG---INYKGRLFVSDRAHLVF
A.thaliana|TAIR:gene:2076605 ALHLVPSGILNEDTTCVIGNGVVVHLPGLFKEIDGLESNG---VSCKGRILVSDRAHLLF
S.cerevisiae|SGD:S000005164 DFHMLPSGLVNPNCQNLLGNGVVIHVPSFFKELETLEAK--GLKNARSRLFVSSRAHLVF
S.pombe|SPAC144.03 DFHILPSGLVNPKCQNLIGSGVVVYLPAFFSELEKLEQK--GLK-CRDRIFISDRAHLVF
R.norvegicus|RGD:1310508 DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLDGWEKRLIISDRAHIVF
M.musculus|MGI:87948 DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLDGWEKRLIISDRAHIVF
H.sapiens|UniProtKB:P30520 DFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVF
G.gallus|UniProtKB:Q5ZJL5 DFHLLPSGIINPKVTAFIGNGVVIHLPGLFEETEKNLKKGKGLEGWEKRLVISDRAHIVF
D.rerio|ZFIN:ZDB-GENE-050417-337 DFHLLPSGIINPKVTAFIGNGVVIHLPGLFEEAEKNVRKGKGLEGWESRLIISDRAHIVF
R.norvegicus|RGD:1590342 DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKK--GLKDWEKRLIISDRAHLVF
M.musculus|MGI:87947 DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKK--GLKDWEKRLIISDRAHLVF
H.sapiens|UniProtKB:Q8N142 DFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKK--GLKDWEKRLIISDRAHLVF
G.gallus|RefSeq:XP_001235680 DFHLFPSGIINPKAISFIGNGVVIHLPGLFEEAEKNEKK--GLKDWEKRLIISDRAHIVF
D.rerio|ZFIN:ZDB-GENE-040516-18 DFHLLPSGIINTKCTSFIGNGVVIHLPGLFEEIDKNEKK--GLKGWEKRLVISDRAHIVF
D.rerio|ZFIN:ZDB-GENE-020419-28 DFHLLPSGVLNKKATSFIGNGVVIHLPGLFDEAEKNLQKGNGLQGWEERLKISDRAHIVF
D.melanogaster|FB:FBgn0027493 DFHLLPSGVVNEKCVSVIGNGVVIHLPSLFDEVLKNEAK--GLQHLENRLIISDRAHLVF
C.elegans|WP:WB:CE08630 DFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILE--ESGWEKRIMISSEAHLVF
C.elegans|WB:WBGene00016509 DFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILE--ESGWEKRIMISSEAHLVF
C.elegans|UniProtKB:Q8MNS2 DFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILE--ESGWEKRIMISSEAHLVF
C.elegans|WP:WB:CE29709 DFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILE--ESGWEKRIMISSEAHLVF
C.elegans|UniProtKB:P91134 DFHILPSGIISPTCFNVIGNGVVVNLDAFFSELAHNGILE--ESGWEKRIMISSEAHLVF
E.coli|P0A7D4 VLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRG---IPVRERLLLSEACPLIL
:*:.***:: .:*.*:*: ::.* . *: :*. . :::
D.discoideum|dictyBase:DDB0201565 DLHQMIDAMKEA-ELSNGTSNDSIGTTKRGIGPCYSSKASRGGLRVCDLYSP-----EHF
A.thaliana|TAIR:gene:2076605 DFHQEVDGLRES-ELAK----SFIGTTKRGIGPAYSSKVIRNGIRVGDLRHM-----DTL
S.cerevisiae|SGD:S000005164 DFHQVTDKLRELELSGRSKDGKNIGTTGKGIGPTYSTKASRSGLRVHHLVNDQPGAWEEF
S.pombe|SPAC144.03 DYHQRADALNEAELGKQS-----IGTTGKGIGPAYSTKATRSGIRVHHLYH-----WAEF
R.norvegicus|RGD:1310508 DFHQAADGIQE--QQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGF
M.musculus|MGI:87948 DFHQAADGIQE--QQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGF
H.sapiens|UniProtKB:P30520 DFHQAADGIQE--QQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDGF
G.gallus|UniProtKB:Q5ZJL5 DFHQAADGIQE--QQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD----FDEF
D.rerio|ZFIN:ZDB-GENE-050417-337 DFHQAVDGVQE--QERQQQAGKNLGTTKKGIGPVYSAKAARSGLRICDLLAD----FQEF
R.norvegicus|RGD:1590342 DFHQAVDGLQE--VQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEF
M.musculus|MGI:87947 DFHQAVDGLQE--VQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEF
H.sapiens|UniProtKB:Q8N142 DFHQAVDGLQE--VQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEF
G.gallus|RefSeq:XP_001235680 DFHQAVDGLQE--VQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD----FDEF
D.rerio|ZFIN:ZDB-GENE-040516-18 DFHQAVDGLQE--TQRQAQEGKNIGTTKKGIGPTYACKASRTGLRICDLMAD----FNEF
D.rerio|ZFIN:ZDB-GENE-020419-28 NFHQAVDGIQE--QLRQQQAGKNLGTTKKGIGPAYSSKAARNGLRVCDLVSD----FSVF
D.melanogaster|FB:FBgn0027493 DFHQHVDGMQE--AEK---GGKSLGTTKKGIGPAYSSKATRNGIRVGELLGD----FNLF
C.elegans|WP:WB:CE08630 GVHSQVDGRQE----DSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMAD----FEEF
C.elegans|WB:WBGene00016509 GVHSQVDGRQE----DSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMAD----FEEF
C.elegans|UniProtKB:Q8MNS2 GVHSQVDGRQE----DSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMAD----FEEF
C.elegans|WP:WB:CE29709 GVHSQVDGRQE----DSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMAD----FEEF
C.elegans|UniProtKB:P91134 GVHSQVDGRQE----DSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMAD----FEEF
E.coli|P0A7D4 DYHVALDNARE-----KARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDK-----ETF
. * * .* :*** :**** * * * *:*: .* :
D.discoideum|dictyBase:DDB0201565 RKTFTRLVENK----HKRFGSFEYD---VEAELKRYQEFAEMLKP--FVIDSVYYLNQAF
A.thaliana|TAIR:gene:2076605 PQKLDLLLSDA----AARFQGFKYTPEMLREEVEAYKRYADRLEP--YITDTVHFINDSI
S.cerevisiae|SGD:S000005164 VARYKRLLETR----RQRYGDFEYD---FEAKLAEYKKLREQLKP--FVVDSVVFMHNAI
S.pombe|SPAC144.03 EARYRKNVADL----QKRYGAFEYD---VEAELIRYKELAQRLKP--FVIDAVAFMYEAL
R.norvegicus|RGD:1310508 SERFKVLANQY----KSIYPTLEID---IEGELQQLKGYMERIKP--MVRDGVYFLYEAL
M.musculus|MGI:87948 SERFKVLANQY----KSIYPTLEID---IEGELQQLKGYMERIKP--MVKDGVYFLYEAL
H.sapiens|UniProtKB:P30520 SERFKVLANQY----KSIYPTLEID---IEGELQKLKGYMEKIKP--MVRDGVYFLYEAL
G.gallus|UniProtKB:Q5ZJL5 SERFKVLANQY----KAIYPTLEID---IEGELKKLKAYMEKVKP--MVKDGVYFMYEAL
D.rerio|ZFIN:ZDB-GENE-050417-337 SERFKHLASQY----KSMYPSLEID---VDGELEKLKSYVDRIKP--MVRDGVFFMYEAL
R.norvegicus|RGD:1590342 SARFKNLAHQH----QSMFPTLEID---VEGQLKRLKGFAERIRP--MVRDGVYFMYEAL
M.musculus|MGI:87947 SARFKNLAHQH----QSMFPTLEID---VEGQLKRLKGFAERIRP--MVRDGVYFMYEAL
H.sapiens|UniProtKB:Q8N142 SSRFKNLAHQH----QSMFPTLEID---IEGQLKRLKGFAERIRP--MVRDGVYFMYEAL
G.gallus|RefSeq:XP_001235680 SSRFKNLAQQY----KSMFPTLDID---IEGQLKKLKGYAEKIRP--MVRDGVYFMYEAL
D.rerio|ZFIN:ZDB-GENE-040516-18 STRVKNLVQQY----QSMYPTLKVD---VESELKKLKEYAERIRP--LVRDGVYFMYDAI
D.rerio|ZFIN:ZDB-GENE-020419-28 EEKFRVLAGHY----QTTYPNLNID---IDAELQQLKNFAERLRP--LVTDGVYFMHKAL
D.melanogaster|FB:FBgn0027493 SEKFKSIVATH----VRLFPSINVD---VEAELARYKDYADKVRP--YVKDTICFLHTAL
C.elegans|WP:WB:CE08630 SEKYRRLVEHY----KKQFPSIEVN---VDEELAKFKQHREKLAELKLVGDTVGFIHEQR
C.elegans|WB:WBGene00016509 SEKYRRLVEHY----KKQFPSIEVN---VDEELAKFKQHREKLAELKLVGDTVGFIHEQR
C.elegans|UniProtKB:Q8MNS2 SEKYRRLVEHY----KKQFPSIEVN---VDEELAKFKQHREKLAELKLVGDTVGFIHEQR
C.elegans|WP:WB:CE29709 SEKYRRLVEHY----KKQFPSIEVN---VDEELAKFKQHREKLAELKLVGDTVGFIHEQR
C.elegans|UniProtKB:P91134 SEKYRRLVEHY----KKQFPSIEVN---VDEELAKFKQHREKLAELKLVGDTVGFIHEQR
E.coli|P0A7D4 AEKLKEVMEYHNFQLVNYYKAEAVD---YQKVLDDTMAVADILTS--MVVDVSDLLDQAR
: : : : : * :
D.discoideum|dictyBase:DDB0201565 KDG-KKVLIEGAQSTMLDLDFGCYPYVTSSASSVGGACTGLGISPNKVVTQIGVVKAYTT
A.thaliana|TAIR:gene:2076605 SQK-KKVLVEGGQATMLDIDFGTYPFVTSSSPSAGGICTGLGIAPSVVGDLIGVVKAYTT
S.cerevisiae|SGD:S000005164 EAK-KKILVEGANALMLDIDFGTYPYVTSSNTGIGGVLTGLGIPPRTIDEIYGVVKAYTT
S.pombe|SPAC144.03 QSK-KRILVEGANALMLDLDFGTYPFVTSSNTTVGGVCTGLGVPPQRIANSIGVVKAYTT
R.norvegicus|RGD:1310508 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT
M.musculus|MGI:87948 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT
H.sapiens|UniProtKB:P30520 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT
G.gallus|UniProtKB:Q5ZJL5 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT
D.rerio|ZFIN:ZDB-GENE-050417-337 HGDPKRILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT
R.norvegicus|RGD:1590342 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT
M.musculus|MGI:87947 HGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT
H.sapiens|UniProtKB:Q8N142 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT
G.gallus|RefSeq:XP_001235680 HGSPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGVPPQHVGDVYGVVKAYTT
D.rerio|ZFIN:ZDB-GENE-040516-18 HGPQKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPANIGDVYGVSKAYTT
D.rerio|ZFIN:ZDB-GENE-020419-28 TGPSKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPSHVGRVYGVVKAYTT
D.melanogaster|FB:FBgn0027493 RNG-KTILVEGANAAMLDIDFGTYPYVTSSNCSIGGVLTGLGLPPQTIGEVIGVVKAYTT
C.elegans|WP:WB:CE08630 NAG-KQVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQT
C.elegans|WB:WBGene00016509 NAG-KQVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQT
C.elegans|UniProtKB:Q8MNS2 NAG-KQVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQT
C.elegans|WP:WB:CE29709 NAG-KQVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQT
C.elegans|UniProtKB:P91134 NAG-KQVLVEGANGALLDIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQT
E.coli|P0A7D4 QRG-DFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYST
. ::.**.:. :**:*.* **:**** ** ** *: * : *: *** *
D.discoideum|dictyBase:DDB0201565 KVGSGPFPTEQNDHVGDSLRKAGSEFGTTTGRPRRIGWLDAVVLRYTSMINDFTRLNLTK
A.thaliana|TAIR:gene:2076605 RVGSGPFPTENLGTGGDLLRLAGQEFGTTTGRPRRCGWLDIVALKFSCQINGFASLNLTK
S.cerevisiae|SGD:S000005164 RVGEGPFPTEQLNENGEKLQTIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITK
S.pombe|SPAC144.03 RVGAGPFPTEQLNEIGDHLQSVGREVGVTTGRKRRCGWLDLVVVKYSTMINGYTSLNLTK
R.norvegicus|RGD:1310508 RVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTK
M.musculus|MGI:87948 RVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVSLKYAHMINGFTALALTK
H.sapiens|UniProtKB:P30520 RVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTK
G.gallus|UniProtKB:Q5ZJL5 RVGIGAFPTEQDNEIGELLQMRGKEFGVTTGRKRRCGWLDLVQLRYAYMINGFTALALTK
D.rerio|ZFIN:ZDB-GENE-050417-337 RVGIGAFPTEQSNETGELLQTRGKEVGVTTGRKRRCGWLDLVLIKYAHMINGFTALALTK
R.norvegicus|RGD:1590342 RVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK
M.musculus|MGI:87947 RVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK
H.sapiens|UniProtKB:Q8N142 RVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK
G.gallus|RefSeq:XP_001235680 RVGIGAFPTEQINEIGDLLQSRGHEWGVTTGRKRRCGWLDLVILKYAHMINGFTALALTK
D.rerio|ZFIN:ZDB-GENE-040516-18 RVGIGAFPTEQLNAVGELLQTRGHEVGVTTGRKRRCGWLDLVILKYAHMINGFTAIALTK
D.rerio|ZFIN:ZDB-GENE-020419-28 RVGVGAFPTEQNNEIGDLLQSRGREFGVTTGRRRRCGWLDLVLVRYAHMVNGFSAIALTK
D.melanogaster|FB:FBgn0027493 RVGDGPFPTEQLNDIGDLLQTRGFEVGVTTKRKRRCGWLDIPLLKYTSLVNGYTCICLTK
C.elegans|WP:WB:CE08630 RVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTK
C.elegans|WB:WBGene00016509 RVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTK
C.elegans|UniProtKB:Q8MNS2 RVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTK
C.elegans|WP:WB:CE29709 RVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTK
C.elegans|UniProtKB:P91134 RVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTK
E.coli|P0A7D4 RVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTK
:** *.**** . * * * * *.** * ** **:* :: : :*. : : :**
D.discoideum|dictyBase:DDB0201565 LDVLSDFEEIKIGVDYK-YKGETIKSFPASLETLAQCEVVYESFPGWKCDLSHVTEYDQL
A.thaliana|TAIR:gene:2076605 LDVLSDLNEIQLGVAYKRSDGTPVKSFPGDLRLLEELHVEYEVLPGWKSDISSVRNYSDL
S.cerevisiae|SGD:S000005164 LDVLDTFKEIPVGISYS-IQGKKLDLFPEDLNILGKVEVEYKVLPGWDQDITKITKYEDL
S.pombe|SPAC144.03 LDILDALDEIKVAVAYI-INGKRIETFPADLDSLEEAEIVYETFPGWKVPTTGITHWDQM
R.norvegicus|RGD:1310508 LDILDMFTEIKVGVAYK-LDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKEL
M.musculus|MGI:87948 LDILDMFTEIKVGVAYK-LDGETIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKEL
H.sapiens|UniProtKB:P30520 LDILDMFTEIKVGVAYK-LDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKEL
G.gallus|UniProtKB:Q5ZJL5 LDILDVFPEIKVGVAYK-LDGEVIPHFPANHEVLSKVEVKYETLPGWDTDISNARTFDEL
D.rerio|ZFIN:ZDB-GENE-050417-337 LDILDVLPEIKVGVAYK-VNGETIPHFPANQEVLQKVEVEYETLPGWSTDTSAVRTFEEL
R.norvegicus|RGD:1590342 LDILDVLSEIKVGISYK-LNGKRIPYFPGM------------------------------
M.musculus|MGI:87947 LDILDVLSEIKVGISYK-LNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDL
H.sapiens|UniProtKB:Q8N142 LDILDVLGEVKVGVSYK-LNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDL
G.gallus|RefSeq:XP_001235680 LDILDVLDEIKIGVAYK-LGGKRIPYFPANQEILQKVEVEYETMPGWKTDTTGARKWEDL
D.rerio|ZFIN:ZDB-GENE-040516-18 LDILDVLDEIKVGVAYK-INGKRIPHFPANLEVLQKVEVEYETFPGWKSDTSAARKWGDL
D.rerio|ZFIN:ZDB-GENE-020419-28 LDILDTLPEIKIGTAYT-VDGKPLPSFPANMDMLTKVQVTYETFPGWSCSTEGVRSFDEL
D.melanogaster|FB:FBgn0027493 LDILDTLPEIKVAVAYKKPNGEKLDHFPGTIAELGNIEVEYAVLPGWQTSTEEVRNFKEL
C.elegans|WP:WB:CE08630 LDILDTFPTIKVAVGYK-LNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDL
C.elegans|WB:WBGene00016509 LDILDTFPTIKVAVGYK-LNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDL
C.elegans|UniProtKB:Q8MNS2 LDILDTFPTIKVAVGYK-LNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDL
C.elegans|WP:WB:CE29709 LDILDTFPTIKVAVGYK-LNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDL
C.elegans|UniProtKB:P91134 LDILDTFPTIKVAVGYK-LNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDL
E.coli|P0A7D4 LDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
**:*. : : : * * : *
D.discoideum|dictyBase:DDB0201565 PIQAKNYIKRIEELVGVPIVYIGVGVER-KNLIERKELI-
A.thaliana|TAIR:gene:2076605 PKAAQQYVERIEELVGVPIHYIGIGPGR-DALIYK-----
S.cerevisiae|SGD:S000005164 PENAKKYLKYIEDFVGVPVEWVGTGPAR-ESMLHKEIK--
S.pombe|SPAC144.03 PENAKKYIEFIEKFVGVPITFIGVGPGR-DEMLVKE----
R.norvegicus|RGD:1310508 PVNAQNYVRFIEDELQIPVKWIGVGKSR-ESMIQLF----
M.musculus|MGI:87948 PVNAQNYVRFIEDELQIPVKWIGVGKSR-ESMIQLF----
H.sapiens|UniProtKB:P30520 PVNAQNYVRFIEDELQIPVKWIGVGKSR-ESMIQLF----
G.gallus|UniProtKB:Q5ZJL5 PVNAQNYVRFIEMELGVPVKWIGVGKSR-ESMIQLF----
D.rerio|ZFIN:ZDB-GENE-050417-337 PENAKKYVCFIEDRLGVPVKWIGVGKSR-ESMIQLF----
R.norvegicus|RGD:1590342 ----------------------------------------
M.musculus|MGI:87947 PPQAQSYVRFVENHMGVAVKWVGVGKSR-ESMIQLF----
H.sapiens|UniProtKB:Q8N142 PPQAQNYIRFVENHVGVAVKWVGVGKSR-ESMIQLF----
G.gallus|RefSeq:XP_001235680 PPKAQNYIRCVENHVGVPVKWVGVGKSR-ESMIQLF----
D.rerio|ZFIN:ZDB-GENE-040516-18 PAKAQNYIRFVENHIGVPIKWVGVGKSR-ECMIQMF----
D.rerio|ZFIN:ZDB-GENE-020419-28 PTQAQSYIKFIEDFLQVPVKWVGVGKSR-ESMIKLF----
D.melanogaster|FB:FBgn0027493 PENAQSYVRLLESELSVPVRWVGVGKGR-ESIINVH----
C.elegans|WP:WB:CE08630 PEKCRQYVKFIEDFIKVPIVYIGVGAER-ESLIVRQQ---
C.elegans|WB:WBGene00016509 PEKCRQYVKFIEDFIKVPIVYIGVGAER-ESLIVRQQ---
C.elegans|UniProtKB:Q8MNS2 PEKCRQYVKFIEDFIKVPIVYIGVGAER-ESLIVRQQ---
C.elegans|WP:WB:CE29709 PEKCRQYVKFIEDFIKVPIVYIGVGAER-ESLIVRQQ---
C.elegans|UniProtKB:P91134 PEKCRQYVKFIEDFIKVPIVYIGVGAER-ESLIVRQQ---
E.coli|P0A7D4 PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
